Search Results - "MENDIS, THILINI"
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Affinity purification of serum-derived anti-IA-2 autoantibodies in type 1 diabetes using a novel MBP-IA-2 fusion protein
Published in Biochemistry and biophysics reports (01-03-2023)“…Autoantibodies targeting epitopes contained within the intracellular domain (IC) of the protein phosphatase-like islet antigen 2 (IA-2) are a common marker of…”
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250-LB: Affinity Purification and Identification of Unique, Shared, Anti-IA-2 B-Cell Clonotypes: A Proteomic Approach to Understanding Pathophysiological Mechanisms Underpinning Humoral Autoimmunity in Type 1 Diabetes
Published in Diabetes (New York, N.Y.) (01-06-2019)“…Immune destruction of beta (β) cells is a feature of type 1 diabetes (T1D), yet the pathophysiological role of autoantibodies (Abs) is poorly understood…”
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A cell-based assay for the detection of pathogenic anti-voltage-gated calcium channel autoantibodies in immunoglobulin G from patients with type 1 diabetes
Published in Journal of immunological methods (01-09-2018)“…Recent studies have postulated the presence of functional autoantibodies (Abs) against L-type voltage gated calcium channels (VGCCs) in the serum of patients…”
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