Search Results - "MENDELSON, C. R"

Role of transcription factors in fetal lung development and surfactant protein gene expression by Mendelson, C R

“…Branching morphogenesis of the lung and differentiation of specialized cell populations is dependent upon reciprocal interactions between epithelial cells…”
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Hypoxia Prevents Induction of Aromatase Expression in Human Trophoblast Cells in Culture: Potential Inhibitory Role of the Hypoxia-Inducible Transcription Factor Mash-2 (Mammalian Achaete-Scute Homologous Protein-2) by Jiang, Bing, Kamat, Amrita, Mendelson, Carole R

“…The human placenta has a remarkable capacity to aromatize C19-steroids, produced by the fetal adrenals, to estrogens. This reaction is catalyzed by aromatase…”
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Structural analysis of the gene encoding human aromatase cytochrome P-450, the enzyme responsible for estrogen biosynthesis by Means, G D, Mahendroo, M S, Corbin, C J, Mathis, J M, Powell, F E, Mendelson, C R, Simpson, E R

“…The structural gene encoding aromatase cytochrome P-450 (P-450AROM) was isolated from human genomic DNA. The gene spans at least 52 kilobases and is composed…”
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Tissue-specific and hormonally controlled alternative promoters regulate aromatase cytochrome P450 gene expression in human adipose tissue by MAHENDROO, M. S, MENDELSON, G. R, SIMPSON, E. R

“…Estrogen biosynthesis is catalyzed by a microsomal enzyme, aromatase cytochrome P450 (P450arom; the product of the CYP19 gene). The human CYP19 gene comprises…”
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Isolation of a Full-Length cDNA Insert Encoding Human Aromatase System Cytochrome P-450 and Its Expression in Nonsteroidogenic Cells by Corbin, C. Jo, Graham-Lorence, Sandra, McPhaul, Michael, Mason, J. Ian, Mendelson, Carole R., Simpson, Evan R.

“…The isolation and cloning of a full-length cDNA insert complementary to mRNA encoding human aromatase system cytochrome P-450 is reported. The insert contains…”
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Human SP-A1 and SP-A2 genes are differentially regulated during development and by cAMP and glucocorticoids by McCormick, S M, Mendelson, C R

“…Expression of the surfactant protein A (SP-A) gene is lung specific, developmentally induced, and regulated by adenosine 3',5'-cyclic monophosphate (cAMP) and…”
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Tissue-specific expression of human P-450AROM. The promoter responsible for expression in adipose tissue is different from that utilized in placenta by MAHENDROO, M. S, MEANS, G. D, MENDELSON, C. R, SIMPSON, E. R

“…The biosynthesis of estrogens from androgens is catalyzed by a enzyme of the endoplasmic reticulum termed aromatase cytochrome P-450 (P-450AROM). The gene…”
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Transcriptional regulation of CYP19 gene (aromatase) expression in adipose stromal cells in primary culture by Zhao, Ying, Agarwal, Veena R., Mendelson, Carole R., Simpson, Evan R.

“…Estrogen biosynthesis in adipose tissue increases with age and obesity, and has been implicated in the development of endometrial cancer and breast cancer. In…”
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The major apoprotein of rabbit pulmonary surfactant. Elucidation of primary sequence and cyclic AMP and developmental regulation by Boggaram, V, Qing, K, Mendelson, C R

“…The major apoprotein of rabbit pulmonary surfactant is a developmentally and hormonally regulated sialoglycoprotein, Mr congruent to 29,000-36,000 (SP 29-36)…”
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Estrogen biosynthesis proximal to a breast tumor is stimulated by PGE2 via cyclic AMP, leading to activation of promoter II of the CYP19 (aromatase) gene by Zhao, Y, Agarwal, V R, Mendelson, C R, Simpson, E R

“…In the present report, we show that prostaglandin (PG) E2 is the most potent factor which stimulates aromatase expression via cyclic AMP and promoter II. PGE2…”
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Immunolocalization of aromatase, 17α-hydroxylase and side-chain-cleavage cytochromes P-450 in the human ovary by Sasano, H, Okamoto, M, Mason, J I, Simpson, E R, Mendelson, C R, Sasano, N, Silverberg, S G

“…Immunohistochemical localization of cholesterol side-chain-cleavage, 17α-hydroxylase and aromatase cytochromes P-450 was performed in 35 morphologically normal…”
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Characterization of mRNA transcripts and organization of human SP-A1 and SP-A2 genes by McCormick, S M, Boggaram, V, Mendelson, C R

“…In the present study, we have characterized the mRNA transcripts and intron-exon organization of the human surfactant protein (SP)A1 and SP-A2 genes. By primer…”
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Tissue-specific promoters regulate aromatase cytochrome P450 gene expression in human ovary and fetal tissues by Means, G D, Kilgore, M W, Mahendroo, M S, Mendelson, C R, Simpson, E R

“…The formation of estrogens from C19 steroids is catalyzed by a specific form of cytochrome P450, aromatase cytochrome P450 (P450AROM; the product of the CYP19…”
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Hormonal control of the surfactant system in fetal lung by Mendelson, C R, Boggaram, V

“…The synthesis of surfactant glycerophospholipids and proteins is under multifactorial control and is regulated by a number of hormones and factors, including…”
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Transcriptional regulation of the gene encoding the major surfactant protein (SP-A) in rabbit fetal lung by Boggaram, V, Mendelson, C R

“…The expression of the major protein of rabbit pulmonary surfactant (SP-A), a glycoprotein of Mr congruent to 29,000-36,000, is regulated during development and…”
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A CRE-like element plays an essential role in cAMP regulation of human SP-A2 gene in alveolar type II cells by Young, P P, Mendelson, C R

“…The human has two genes encoding surfactant protein-A (SP-A), termed SP-A1 and SP-A2; the SP-A2 gene is more highly regulated by cAMP and during fetal…”
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The expression of a functional cDNA encoding the chicken cytochrome P-450arom (aromatase) that catalyzes the formation of estrogen from androgen by McPhaul, M J, Noble, J F, Simpson, E R, Mendelson, C R, Wilson, J D

“…A complementary DNA (cDNA) copy of the aromatase P-450 has been isolated from a chicken ovary library using as probe a partial cDNA believed to encode the…”
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Regulation of estrogen biosynthesis by human adipose cells by Simpson, E R, Merrill, J C, Hollub, A J, Graham-Lorence, S, Mendelson, C R

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Regulation of expression of the gene encoding the major surfactant protein (SP-A) in human fetal lung in vitro. Disparate effects of glucocorticoids on transcription and on mRNA stability by VIJAYAKUMAR BOGGARAM, SMITH, M. E, MENDELSON, C. R

“…We previously observed that dexamethasone had a biphasic effect on the levels of mRNA encoding the major surfactant protein (SP-A) in human fetal lung in…”
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Structure-function relationships of human aromatase cytochrome P-450 using molecular modeling and site-directed mutagenesis by GRAHAM-LORENCE, S, KHALIL, M. W, LORENCE, M. C, MENDELSON, C. R, SIMPSON, E. R

“…The conversion of androgens to estrogens is catalyzed by an enzyme complex named aromatase, which consists of a form of cytochrome P-450, aromatase cytochrome…”
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