Search Results - "MENDELOW, A. D"

Increased expression of fatty acid binding protein 4 and leptin in resident macrophages characterises atherosclerotic plaque rupture by Lee, K, Santibanez-Koref, M, Polvikoski, T, Birchall, D, Mendelow, A.D, Keavney, B

“…Abstract Objective Resident macrophages play an important role in atheromatous plaque rupture. The macrophage gene expression signature associated with plaque…”
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Intraventricular hemorrhage and hydrocephalus after spontaneous intracerebral hemorrhage: results from the STICH trial by Bhattathiri, P S, Gregson, B, Prasad, K S M, Mendelow, A D

“…Intraventricular hemorrhage (IVH), either independent of or as an extension of intracranial bleed, is thought to carry a grave prognosis. Although the effect…”
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Critical thresholds of intracranial pressure and cerebral perfusion pressure related to age in paediatric head injury by Chambers, I R, Jones, P A, Lo, T Y M, Forsyth, R J, Fulton, B, Andrews, P J D, Mendelow, A D, Minns, R A

“…Background: The principal strategy for managing head injury is to reduce the frequency and severity of secondary brain insults from intracranial pressure (ICP)…”
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Decompressive craniectomy in traumatic brain injury: the randomized multicenter RESCUEicp study (www.RESCUEicp.com) by Hutchinson, P J, Corteen, E, Czosnyka, M, Mendelow, A D, Menon, D K, Mitchell, P, Murray, G, Pickard, J D, Rickels, E, Sahuquillo, J, Servadei, F, Teasdale, G M, Timofeev, I, Unterberg, A, Kirkpatrick, P J

“…The RESCUEicp (Randomized Evaluation of Surgery with Craniectomy for Uncontrollable Elevation of intracranial pressure) study has been established to determine…”
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Surgery in intracerebral hemorrhage. The uncertainty continues by Fernandes, H M, Gregson, B, Siddique, S, Mendelow, A D

“…Primary intracerebral hemorrhage (ICH) accounts for 10% to 20% of stroke but carries the highest rates of mortality and morbidity of all stroke subtypes…”
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Predicting the risk of rupture of intracranial aneurysms based on anatomical location by Clarke, G, Mendelow, A D, Mitchell, P

“…The location of intracranial aneurysms may be a significant independent risk factor for predicting aneurysm rupture. A recent report found high bleed rates…”
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Risk–benefit analysis of the treatment of unruptured intracranial aneurysms by Vindlacheruvu, R R, Mendelow, A D, Mitchell, P

“…Objectives: To determine under what circumstances repair of unruptured intracranial aneurysms may be beneficial. Methods: A life expectancy analysis of…”
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Bispectral index monitoring may not reliably indicate cerebral ischaemia during awake carotid endarterectomy by Deogaonkar, A., Vivar, R., Bullock, R. E., Price, K., Chambers, I., Mendelow, A. D.

“…Background. Intraoperative ischaemia during carotid cross-clamping in patients undergoing carotid endarterectomy (CEA) is a major complication and prompt…”
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Temporal trends in head injury outcomes from 2003 to 2009 in England and Wales by Fuller, G., Bouamra, O., Woodford, M., Jenks, T., Patel, H., Coats, T. J, Oakley, P., Mendelow, A.D., Pigott, T., Hutchinson, P. J, Lecky, F.

“…Background: Case fatality rates after blunt head injury (HI) did not improve in England and Wales between 1994 and 2003. The United Kingdom National Institute…”
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Serum concentration of adhesion molecules in patients with delayed ischaemic neurological deficit after aneurysmal subarachnoid haemorrhage: the immunoglobulin and selectin superfamilies by Nissen, J J, Mantle, D, Gregson, B, Mendelow, A D

“…OBJECTIVES Adhesion molecules are involved in the pathogenesis of cerebral ischaemia and may play a part in the pathophysiology of delayed ischaemic…”
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Endovascular stenting of the transverse sinus in a patient presenting with benign intracranial hypertension by Ogungbo, B, Roy, D, Gholkar, A, Mendelow, AD

“…The authors present a 37-year-old lady with symptoms and signs suggestive of benign intracranial hypertension (BIH). Routine CT and MRI scans were normal…”
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Determination of threshold levels of cerebral perfusion pressure and intracranial pressure in severe head injury by using receiver-operating characteristic curves : an observational study in 291 patients by CHAMBERS, Iain Robert, TREADWELL, Lynne, MENDELOW, A. David

“…Intracranial pressure (ICP) and cerebral perfusion pressure (CPP) are frequently monitored in severely head injured patients. To establish which one (ICP or…”
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Mechanisms of ischemic brain damage with intracerebral hemorrhage by Mendelow, A D

“…The results of surgical evacuation of spontaneous intracerebral hematomas are disappointing. This is largely because experimental studies have now confirmed…”
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Clinical comparison of tympanic membrane displacement with invasive intracranial pressure measurements by Shimbles, S, Dodd, C, Banister, K, Mendelow, A D, Chambers, I R

“…A non-invasive method of assessing intracranial pressure (ICP) would be of benefit to patients with abnormal cerebral pathology that could give rise to changes…”
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Head injuries: a study evaluating the impact of the NICE head injury guidelines by Hassan, Z, Smith, M, Littlewood, S, Bouamra, O, Hughes, D, Biggin, C, Amos, K, Mendelow, A D, Lecky, F

“…Background: The NICE head injury guidelines recommend a different approach in the management of head injury patients. It suggests that CT head scan should…”
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Age-related differences in intracranial pressure and cerebral perfusion pressure in the first 6 hours of monitoring after children's head injury: association with outcome by Chambers, I R, Stobbart, L, Jones, P A, Kirkham, F J, Marsh, M, Mendelow, A D, Minns, R A, Struthers, S, Tasker, R C

“…Severe head injury in childhood is associated with considerable mortality and morbidity. In this study we determined age-related differences in the…”
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Prognostic implications of p53 protein, epidermal growth factor receptor, and Ki-67 labelling in brain tumours by JAROS, E, PERRY, R. H, ADAM, L, KELLY, P. J, CRAWFORD, P. J, KALBAG, R. M, MENDELOW, A. D, SENGUPTA, R. P, PEARSON, A. D. J

“…The expression of p53 protein, epidermal growth factor receptor (EGFR), and Ki-67 nuclear antigen was examined by immunohistochemistry in biopsies of 16 types…”
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Clinical comparison of the Spiegelberg parenchymal transducer and ventricular fluid pressure by Chambers, I R, Siddique, M S, Banister, K, Mendelow, A D

“…The Spiegelberg brain pressure catheter is a low cost implantable intracranial pressure measuring system which has the unique ability to perform regular…”
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Recommendations from the Society of British Neurological Surgeons by BARTLETT, J., KETT-WHITE, R., MENDELOW, A. D., MILLER, J. D., PICKARD, J., TEASDALE, G.

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Trends over time in the management of subarachnoid haemorrhage in Newcastle: review of 1609 patients by Ogungbo, B., Gregson, B. A., Blackburn, A., Mendelow, A. D.

“…This article reviews trends in the management of subarachnoid haemorrhage (SAH) at the Regional Neurosurgery Unit in Newcastle over 9 years. This is a…”
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