Search Results - "MEMO, Massimiliano"

Donor hearts in the Sydney Heart Bank: reliable control but is it ‘normal’ heart? by Marston, Steven, Jacques, Adam, Bayliss, Christopher, Dyer, Emma, Memo, Massimiliano, Papadaki, Maria, Messer, Andrew

“…Human heart samples from the Sydney Heart Bank have become a de facto standard against which others can be measured. Crucially, the heart bank contains a lot…”
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Familial dilated cardiomyopathy mutations uncouple troponin I phosphorylation from changes in myofibrillar Ca²⁺ sensitivity by Memo, Massimiliano, Leung, Man-Ching, Ward, Douglas G, dos Remedios, Cristobal, Morimoto, Sachio, Zhang, Lianfeng, Ravenscroft, Gianina, McNamara, Elyshia, Nowak, Kristen J, Marston, Steven B, Messer, Andrew E

“…The pure form of familial dilated cardiomyopathy (DCM) is mainly caused by mutations in genes encoding sarcomeric proteins. Previous measurements using…”
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Skeletal muscle myopathy mutations at the actin tropomyosin interface that cause gain- or loss-of-function by Memo, Massimiliano, Marston, Steven

“…It is well known that the regulation of muscle contraction relies on the ability of tropomyosin to switch between different positions on the actin filament,…”
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Mutations in repeating structural motifs of tropomyosin cause gain of function in skeletal muscle myopathy patients by Marston, Steven, Memo, Massimiliano, Messer, Andrew, Papadaki, Maria, Nowak, Kristen, McNamara, Elyshia, Ong, Royston, El-Mezgueldi, Mohammed, Li, Xiaochuan, Lehman, William

“…The congenital myopathies include a wide spectrum of clinically, histologically and genetically variable neuromuscular disorders many of which are caused by…”
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Abnormal actin binding of aberrant β-tropomyosins is a molecular cause of muscle weakness in TPM2-related nemaline and cap myopathy by Marttila, Minttu, Lemola, Elina, Wallefeld, William, Memo, Massimiliano, Donner, Kati, Laing, Nigel G, Marston, Steven, Grönholm, Mikaela, Wallgren-Pettersson, Carina

“…NM (nemaline myopathy) is a rare genetic muscle disorder defined on the basis of muscle weakness and the presence of structural abnormalities in the muscle…”
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β Integrin Tyrosine Phosphorylation Is a Conserved Mechanism for Regulating Talin-induced Integrin Activation by Anthis, Nicholas J., Haling, Jacob R., Oxley, Camilla L., Memo, Massimiliano, Wegener, Kate L., Lim, Chinten J., Ginsberg, Mark H., Campbell, Iain D.

“…Integrins are large membrane-spanning receptors fundamental to cell adhesion and migration. Integrin adhesiveness for the extracellular matrix is activated by…”
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Molecular Mechanism of Novel Deletions in TPM3 that cause a Hypercontractile Phenotype with Congenital Muscle Stiffness by Marston, Steven, Papadaki, Maria, Memo, Massimiliano, Messer, Andrew, Donkervoort, Sandra, Bonneman, Carsten, Nowak, Kristen, Ong, Royston, McNamara, Elyshia

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K7del is a common TPM2 gene mutation associated with nemaline myopathy and raised myofibre calcium sensitivity by MOKBEL, Nancy, ILKOVSKI, Biljana, MENARD, Dominique, MARCORELLES, Pascale, ECHANIZ-LAGUNA, Andoni, REIMANN, Jens, VAINZOF, Mariz, MONNIER, Nicole, RAVENSCROFT, Gianina, MCNAMARA, Elyshia, NOWAK, Kristen J, LAING, Nigel G, KREISSL, Michaela, WALLGREN-PETTERSSON, Carina, TREWHELLA, Jill, MARSTON, Steve, OTTENHEIJM, Coen, NORTH, Kathryn N, CLARKE, Nigel F, MEMO, Massimiliano, JEFFRIES, Cy M, MARTTILA, Minttu, LEHTOKARI, Vilma-Lotta, LEMOLA, Elina, GRÖNHOLM, Mikaela, NAN YANG

“…Mutations in the TPM2 gene, which encodes β-tropomyosin, are an established cause of several congenital skeletal myopathies and distal arthrogryposis. We have…”
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Investigation of a transgenic mouse model of familial dilated cardiomyopathy by Song, Weihua, Dyer, Emma, Stuckey, Daniel, Leung, Man-Ching, Memo, Massimiliano, Mansfield, Catherine, Ferenczi, Michael, Liu, Ke, Redwood, Charles, Nowak, Kristen, Harding, Sian, Clarke, Kieran, Wells, Dominic, Marston, Steven

“…Abstract We have investigated a transgenic mouse model of inherited dilated cardiomyopathy that stably expresses the ACTC E361G mutation at around 50% of total…”
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There is a Limit to the Changes in Myofilament Ca2+-Sensitivity due to Myopathies by Messer, Andrew E., Marston, Steven B., Bayliss, Christopher R., Memo, Massimiliano

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Does Uncoupling of Troponin I Phosphorylation from Changes in Myofibrillar Ca2+-Sensitivity Play a Role in the Pathogenesis of Cardiomyopathy? by Messer, Andrew E., Memo, Massimiliano, Bayliss, Christopher R., Ching Leung, Man, Marston, Steven B.

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Mutations in thin Filament Proteins that Cause Familial Dilated Cardiomyopathy Uncouple Troponin I Phosphorylation from Changes in Myofibrillar Ca2+-Sensitivity by Memo, Massimiliano, Messer, Andrew E., Ching Leung, Man, Marston, Steven B.

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Loss of Function in β-Tropomyosin (TPM2) Mutants Causing Nemaline Myopathy or Cap Disease by Memo, Massimiliano, Nuutinen, Elina, Copeland, O'Neal, Wallgren-Pettersson, Carina, Marston, Steven Baxter

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Molecular mechanisms of myopathies by Memo, Massimiliano

“…This study was aimed at the investigation of the mechanisms by which mutations on proteins of the thin filaments could lead to cardiac and skeletal muscle…”
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β Integrin Tyrosine Phosphorylation Is a Conserved Mechanism for Regulating Talin-induced Integrin Activation by Nicholas J. Anthis, Jacob R. Haling, Camilla L. Oxley, Massimiliano Memo, Kate L. Wegener, Chinten J. Lim, Mark H. Ginsberg, Iain D. Campbell

“…Integrins are large membrane-spanning receptors fundamental to cell adhesion and migration. Integrin adhesiveness for the extracellular matrix is activated by…”
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