Search Results - "MELY, Yves"
-
1
Probing Polarity and Heterogeneity of Lipid Droplets in Live Cells Using a Push–Pull Fluorophore
Published in Analytical chemistry (Washington) (05-02-2019)“…Lipid droplets (LDs) are organelles composed of a lipid core surrounded by a phospholipid monolayer. Lately, LDs have attracted considerable attention due to…”
Get full text
Journal Article -
2
Molecular Upconversion in Water in Heteropolynuclear Supramolecular Tb/Yb Assemblies
Published in Journal of the American Chemical Society (30-01-2019)“…Piling up excited states to reach upconversion (UC) is severely restricted by vibrational quenching mechanisms, especially when one looks at discrete molecular…”
Get full text
Journal Article -
3
MemBright: A Family of Fluorescent Membrane Probes for Advanced Cellular Imaging and Neuroscience
Published in Cell chemical biology (18-04-2019)“…The proper staining of the plasma membrane (PM) is critical in bioimaging as it delimits the cell. Herein, we developed MemBright, a family of six…”
Get more information
Journal Article -
4
What Makes Thienoguanosine an Outstanding Fluorescent DNA Probe?
Published in Journal of the American Chemical Society (07-10-2020)“…Thienoguanosine (thG) is an isomorphic guanosine (G) surrogate that almost perfectly mimics G in nucleic acids. To exploit its full potential and lay the…”
Get full text
Journal Article -
5
Switchable Nile Red-Based Probe for Cholesterol and Lipid Order at the Outer Leaflet of Biomembranes
Published in Journal of the American Chemical Society (07-04-2010)“…Cholesterol and sphingomyelin form together a highly ordered membrane phase, which is believed to play important biological functions in plasma membranes of…”
Get full text
Journal Article -
6
Targeted Single Particle Tracking with Upconverting Nanoparticles
Published in ACS applied materials & interfaces (06-03-2024)“…Single particle tracking (SPT) is a powerful technique for real-time microscopic visualization of the movement of individual biomolecules within or on the…”
Get full text
Journal Article -
7
Monitoring Biophysical Properties of Lipid Membranes by Environment-Sensitive Fluorescent Probes
Published in Biophysical journal (06-05-2009)“…We review the main trends in the development of fluorescence probes to obtain information about the structure, dynamics, and interactions in biomembranes…”
Get full text
Journal Article -
8
PvdL Orchestrates the Assembly of the Nonribosomal Peptide Synthetases Involved in Pyoverdine Biosynthesis in Pseudomonas aeruginosa
Published in International journal of molecular sciences (30-05-2024)“…The pyoverdine siderophore is produced by to access iron. Its synthesis involves the complex coordination of four nonribosomal peptide synthetases (NRPSs),…”
Get full text
Journal Article -
9
Collective fluorescence switching of counterion-assembled dyes in polymer nanoparticles
Published in Nature communications (09-06-2014)“…The current challenge in the field of fluorescent nanoparticles (NPs) for bioimaging is to achieve extreme brightness and external control of their emission…”
Get full text
Journal Article -
10
Integrity of lipid nanocarriers in bloodstream and tumor quantified by near-infrared ratiometric FRET imaging in living mice
Published in Journal of controlled release (28-08-2016)“…Lipid nanocarriers are considered as promising candidates for drug delivery and cancer targeting because of their low toxicity, biodegradability and capacity…”
Get full text
Journal Article -
11
Upconversion in a d–f [RuYb3] Supramolecular Assembly
Published in Journal of the American Chemical Society (27-07-2022)“…We have prepared a hetero-tetrametallic assembly consisting of three ytterbium ions coordinated to a central [Ru(bpm)3]2+ (bpm = 2,2′-bipyrimidine) motif…”
Get full text
Journal Article -
12
Conquering 2‑Aminopurine’s Deficiencies: Highly Emissive Isomorphic Guanosine Surrogate Faithfully Monitors Guanosine Conformation and Dynamics in DNA
Published in Journal of the American Chemical Society (11-03-2015)“…The archetypical fluorescent nucleoside analog, 2-aminopurine (2Ap), has been used in countless assays, though it suffers from very low quantum yield,…”
Get full text
Journal Article -
13
Emission Properties of Oxyluciferin and Its Derivatives in Water: Revealing the Nature of the Emissive Species in Firefly Bioluminescence
Published in The journal of physical chemistry. B (12-02-2015)“…The first systematic steady-state and time-resolved emission study of firefly oxyluciferin (emitter in firefly bioluminescence) and its analogues in aqueous…”
Get full text
Journal Article -
14
Assembly dynamics and structure of an aegerolysin, ostreolysin A6
Published in The Journal of biological chemistry (01-08-2023)“…Ostreolysin A6 (OlyA6) is an oyster mushroom-derived membrane-binding protein that, upon recruitment of its partner protein, pleurotolysin B, forms a cytolytic…”
Get full text
Journal Article -
15
Fluorogenic Squaraine Dimers with Polarity-Sensitive Folding As Bright Far-Red Probes for Background-Free Bioimaging
Published in Journal of the American Chemical Society (14-01-2015)“…Polarity-sensitive fluorogenic dyes raised considerable attention because they can turn on their fluorescence after binding to biological targets, allowing…”
Get full text
Journal Article -
16
The epigenetic integrator UHRF1: on the road to become a universal biomarker for cancer
Published in Oncotarget (01-08-2017)“…Cancer is one of the deadliest diseases in the world causing record number of mortalities in both developed and undeveloped countries. Despite a lot of…”
Get full text
Journal Article -
17
Biodistribution of X‑Ray Iodinated Contrast Agent in Nano-Emulsions Is Controlled by the Chemical Nature of the Oily Core
Published in ACS nano (28-10-2014)“…In this study, we investigated the role of the chemical nature of the oil droplet core of nano-emulsions used as contrast agents for X-ray imaging on their…”
Get full text
Journal Article -
18
HIV-1 Gag targeting to the plasma membrane reorganizes sphingomyelin-rich and cholesterol-rich lipid domains
Published in Nature communications (21-11-2023)“…Although the human immunodeficiency virus type 1 lipid envelope has been reported to be enriched with host cell sphingomyelin and cholesterol, the molecular…”
Get full text
Journal Article -
19
Flexible Nature and Specific Functions of the HIV-1 Nucleocapsid Protein
Published in Journal of molecular biology (22-07-2011)“…One salient feature of reverse transcription in retroviruses, notably in the human immunodeficiency virus type 1, is that it requires the homologous…”
Get full text
Journal Article -
20
Natural and Synthetic Anticancer Epidrugs Targeting the Epigenetic Integrator UHRF1
Published in Molecules (Basel, Switzerland) (01-08-2023)“…Cancer is one of the leading causes of death worldwide, and its incidence and mortality are increasing each year. Improved therapeutic strategies against…”
Get full text
Journal Article