Search Results - "MELONI, Giovanna"
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Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin
Published in Proceedings of the National Academy of Sciences - PNAS (11-03-2008)“…Acute myeloid leukemia (AML) carrying NPM1 mutations and cytoplasmic nucleophosmin (NPMc+ AML) accounts for about one-third of adult AML and shows distinct…”
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IKZF1 (Ikaros) Deletions in BCR-ABL1–Positive Acute Lymphoblastic Leukemia Are Associated With Short Disease-Free Survival and High Rate of Cumulative Incidence of Relapse: A GIMEMA AL WP Report
Published in Journal of clinical oncology (01-11-2009)“…The causes of the aggressive nature of BCR-ABL1-positive adult acute lymphoblastic leukemia (ALL) are unknown. To identify, at the submicroscopic level,…”
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3
A sequential approach with imatinib, chemotherapy and transplant for adult Ph+ acute lymphoblastic leukemia: final results of the GIMEMA LAL 0904 study
Published in Haematologica (Roma) (01-12-2016)“…In the GIMEMA LAL 0904 protocol, adult Philadelphia positive acute lymphoblastic leukemia patients were treated with chemotherapy for induction and…”
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Clinico-biological features of 5202 patients with acute lymphoblastic leukemia enrolled in the Italian AIEOP and GIMEMA protocols and stratified in age cohorts
Published in Haematologica (Roma) (01-11-2013)“…The outcome of children and adults with acute lymphoblastic leukemia is markedly different. Since there is limited information on the distribution of…”
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BeEAM (bendamustine, etoposide, cytarabine, melphalan) before autologous stem cell transplantation is safe and effective for resistant/relapsed lymphoma patients
Published in Blood (22-09-2011)“…We designed a phase 1-2 study to evaluate the safety and the efficacy of increasing doses of bendamustine (160 mg/m2, 180 mg/m2, and 200 mg/m2 given on days −7…”
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Daunorubicin Versus Mitoxantrone Versus Idarubicin As Induction and Consolidation Chemotherapy for Adults With Acute Myeloid Leukemia: The EORTC and GIMEMA Groups Study AML-10
Published in Journal of clinical oncology (10-11-2009)“…To compare the antitumor efficacy of three different anthracyclines in combination with cytarabine and etoposide in adult patients with newly diagnosed acute…”
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Impact of induction regimen and allogeneic hematopoietic cell transplantation on outcome in younger adults with acute myeloid leukemia with a monosomal karyotype
Published in Haematologica (Roma) (01-06-2019)“…Monosomal karyotype confers a poor prognosis in patients with acute myeloid leukemia. Here, we determined the impact of the type of remission-induction…”
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Clinically Driven Diagnostic Antifungal Approach in Neutropenic Patients: A Prospective Feasibility Study
Published in Journal of clinical oncology (01-02-2010)“…Preemptive strategies in neutropenic patients based on serum galactomannan (GM) -guided triggering of diagnostic work-up may be time-consuming and expensive…”
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High CD33 expression levels in acute myeloid leukemia cells carrying the nucleophosmin (NPM1) mutation
Published in Haematologica (Roma) (01-10-2011)“…The CD33 antigen is expressed on the blast cells of most cases of acute myeloid leukemia and represents a suitable tumor-associated target antigen for…”
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Posaconazole prophylaxis during front-line chemotherapy of acute myeloid leukemia: a single-center, real-life experience
Published in Haematologica (Roma) (01-04-2012)“…Posaconazole is effective as primary antifungal prophylaxis of invasive fungal diseases in patients with acute myeloid leukemia. The impact of primary…”
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T-cell-replete haploidentical transplantation versus autologous stem cell transplantation in adult acute leukemia: a matched pair analysis
Published in Haematologica (Roma) (01-04-2015)“…Adult patients with acute leukemia in need of a transplant but without a genoidentical donor are usually considered upfront for transplantation with stem cells…”
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Philadelphia-positive acute lymphoblastic leukemia patients already harbor BCR-ABL kinase domain mutations at low levels at the time of diagnosis
Published in Haematologica (Roma) (01-04-2011)“…In patients with Philadelphia-positive acute lymphoblastic leukemia, resistance to treatment with tyrosine kinase inhibitors is frequent and most often…”
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Higher Incidence of Relapse With Peripheral Blood Rather Than Marrow As a Source of Stem Cells in Adults With Acute Myelocytic Leukemia Autografted During the First Remission
Published in Journal of clinical oncology (20-08-2009)“…The cell source for autologous stem cell transplantation has shifted from bone marrow (BM) to peripheral blood (PB). In acute myelocytic leukemia (AML), for…”
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The Molecular Priming of Defense Responses is Differently Regulated in Grapevine Genotypes Following Elicitor Application against Powdery Mildew
Published in International journal of molecular sciences (15-09-2020)“…Molecular changes associated with response to powdery mildew (PM) caused by have been largely explored in cultivars, but little is known on transcriptional and…”
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CRISPR-Cas9-Based Discovery of the Verrucosidin Biosynthesis Gene Cluster in Penicillium polonicum
Published in Frontiers in microbiology (21-05-2021)“…Penicillium polonicum , commonly found on food matrices, is a mycotoxigenic species able to produce a neurotoxin called verrucosidin. This methylated α-pyrone…”
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Low-dose clofarabine in combination with a standard remission induction in patients aged 18-60 years with previously untreated intermediate and bad-risk acute myeloid leukemia or high-risk myelodysplastic syndrome: combined phase I/II results of the EORTC/GIMEMA AML-14A trial
Published in Haematologica (Roma) (01-02-2017)Get full text
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Identical Outcome After Autologous or Allogeneic Genoidentical Hematopoietic Stem-Cell Transplantation in First Remission of Acute Myelocytic Leukemia Carrying Inversion 16 or t(8;21): A Retrospective Study From the European Cooperative Group for Blood and Marrow Transplantation
Published in Journal of clinical oncology (01-07-2008)“…Patients with acute myelocytic leukemia carrying inversion 16 (inv16) or t(8;21) have a better initial response to high-dose cytarabine than patients without…”
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Essential Oils Reduce Grey Mould Rot of Apples and Modify the Fruit Microbiome during Postharvest Storage
Published in Journal of fungi (Basel) (22-12-2022)“…is the causal agent of grey mould rot of apples. The efficacy of biofumigation with thyme ( ), savoury ( ), and basil ( ) essential oils (EOs) at 1%, 0.5%, and…”
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HPLC-MS/MS Method for the Detection of Selected Toxic Metabolites Produced by Penicillium spp. in Nuts
Published in Toxins (08-05-2020)“…spp. are emerging as producers of mycotoxins and other toxic metabolites in nuts. A HPLC-MS/MS method was developed to detect 19 metabolites produced by spp…”
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Impact of FLT3 ITD/NPM1 mutation status in adult patients with acute myelocytic leukemia autografted in first remission
Published in Haematologica (Roma) (01-02-2013)Get full text
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