Search Results - "MELIS, A"

Capitalizing on the heterogeneous effects of CFTR nonsense and frameshift variants to inform therapeutic strategy for cystic fibrosis by Sharma, Neeraj, Evans, Taylor A, Pellicore, Matthew J, Davis, Emily, Aksit, Melis A, McCague, Allison F, Joynt, Anya T, Lu, Zhongzhu, Han, Sangwoo T, Anzmann, Arianna F, Lam, Anh-Thu N, Thaxton, Abigail, West, Natalie, Merlo, Christian, Gottschalk, Laura B, Raraigh, Karen S, Sosnay, Patrick R, Cotton, Calvin U, Cutting, Garry R

“…CFTR modulators have revolutionized the treatment of individuals with cystic fibrosis (CF) by improving the function of existing protein. Unfortunately, almost…”
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LFV and (g-2) in non-universal SUSY models with light higgsinos by Han, C., López-Ibáñez, M.L., Melis, A., Vives, O., Wu, L., Yang, J.M.

“…A bstract We consider a supersymmetric type-I seesaw framework with non-universal scalar masses at the GUT scale to explain the long-standing discrepancy of…”
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Anomaly-free ALP from non-Abelian flavor symmetry by Han, C., López-Ibáñez, M. L., Melis, A., Vives, O., Yang, J. M.

“…A bstract Motivated by the XENON1T excess in electron-recoil measurements, we investigate the prospects of probing axion-like particles (ALP) in lepton flavor…”
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Hydrogeochemical fingerprints of a mixohaline wetland in the Mediterranean: Güllük coastal wetland systems- GCWS (Muğla, Turkey) by SOMAY-ALTAŞ, A. Melis

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Silencing XIST on the future active X: Searching human and bovine preimplantation embryos for the repressor by Aksit, Melis A, Yu, Bo, Roelen, Bernard A J, Migeon, Barbara R

“…X inactivation is the means of equalizing the dosage of X chromosomal genes in male and female eutherian mammals, so that only one X is active in each cell…”
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Increased expression of anion transporter SLC26A9 delays diabetes onset in cystic fibrosis by Lam, Anh-Thu N, Aksit, Melis A, Vecchio-Pagan, Briana, Shelton, Celeste A, Osorio, Derek L, Anzmann, Arianna F, Goff, Loyal A, Whitcomb, David C, Blackman, Scott M, Cutting, Garry R

“…Diabetes is a common complication of cystic fibrosis (CF) that affects approximately 20% of adolescents and 40%-50% of adults with CF. The age at onset of…”
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Evaluation of both exonic and intronic variants for effects on RNA splicing allows for accurate assessment of the effectiveness of precision therapies by Joynt, Anya T, Evans, Taylor A, Pellicore, Matthew J, Davis-Marcisak, Emily F, Aksit, Melis A, Eastman, Alice C, Patel, Shivani U, Paul, Kathleen C, Osorio, Derek L, Bowling, Alyssa D, Cotton, Calvin U, Raraigh, Karen S, West, Natalie E, Merlo, Christian A, Cutting, Garry R, Sharma, Neeraj

“…Elucidating the functional consequence of molecular defects underlying genetic diseases enables appropriate design of therapeutic options. Treatment of cystic…”
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Hydrogen Production. Green Algae as a Source of Energy by Melis, Anastasios, Thomas Happe

“…Hydrogen gas is thought to be the ideal fuel for a world in which air pollution has been alleviated, global warming has been arrested, and the environment has…”
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Modelling annual scintillation arc variations in PSR J1643−1224 using the Large European Array for Pulsars by Mall, G, Main, R A, Antoniadis, J, Bassa, C G, Burgay, M, Chen, S, Cognard, I, Concu, R, Corongiu, A, Gaikwad, M, Hu, H, Janssen, G H, Karuppusamy, R, Kramer, M, Lee, K J, Liu, K, McKee, J W, Melis, A, Mickaliger, M B, Perrodin, D, Pilia, M, Possenti, A, Reardon, D J, Sanidas, S A, Sprenger, T, Stappers, B W, Wang, L, Wucknitz, O, Zhu, W W

“…ABSTRACT In this work, we study variations in the parabolic scintillation arcs of the binary millisecond pulsar PSR J1643−1224 over five years using the Large…”
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Spectropolarimetric observations of the CIZA J2242.8+5301 northern radio relic: no evidence of high-frequency steepening by Loi, F, Murgia, M, Vacca, V, Govoni, F, Melis, A, Wittor, D, Beck, R, Kierdorf, M, Bonafede, A, Boschin, W, Brienza, M, Carretti, E, Concu, R, Feretti, L, Gastaldello, F, Paladino, R, Rajpurohit, K, Serra, P, Vazza, F

“…ABSTRACT Observations of radio relics at very high frequency (>10 GHz) can help to understand how particles age and are (re-)accelerated in galaxy cluster…”
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Genetic Modifiers of Cystic Fibrosis-Related Diabetes Have Extensive Overlap With Type 2 Diabetes and Related Traits by Aksit, Melis A, Pace, Rhonda G, Vecchio-Pagán, Briana, Ling, Hua, Rommens, Johanna M, Boelle, Pierre-Yves, Guillot, Loic, Raraigh, Karen S, Pugh, Elizabeth, Zhang, Peng, Strug, Lisa J, Drumm, Mitch L, Knowles, Michael R, Cutting, Garry R, Corvol, Harriet, Blackman, Scott M

“…Abstract Context Individuals with cystic fibrosis (CF) develop a distinct form of diabetes characterized by β-cell dysfunction and islet amyloid accumulation…”
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Observations of a nearby filament of galaxy clusters with the Sardinia Radio Telescope by Vacca, V, Murgia, M, Govoni, F, Loi, F, Vazza, F, Finoguenov, A, Carretti, E, Feretti, L, Giovannini, G, Concu, R, Melis, A, Gheller, C, Paladino, R, Poppi, S, Valente, G, Bernardi, G, Boschin, W, Brienza, M, Clarke, T E, Colafrancesco, S, Enßlin, T A, Ferrari, C, de Gasperin, F, Gastaldello, F, Girardi, M, Gregorini, L, Johnston-Hollitt, M, Junklewitz, H, Orrù, E, Parma, P, Perley, R, Taylor, G B

“…We report the detection of diffuse radio emission which might be connected to a large-scale filament of the cosmic web covering a 8° × 8° area in the sky,…”
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Variable scintillation arcs of millisecond pulsars observed with the Large European Array for Pulsars by Main, R A, Antoniadis, J, Chen, S, Cognard, I, Hu, H, Jang, J, Karuppusamy, R, Kramer, M, Liu, K, Liu, Y, Mall, G, McKee, J W, Mickaliger, M B, Perrodin, D, Sanidas, S A, Stappers, B W, Sprenger, T, Wucknitz, O, Bassa, C G, Burgay, M, Concu, R, Gaikwad, M, Janssen, G H, Lee, K J, Melis, A, Pilia, M, Possenti, A, Wang, L, Zhu, W W

“…ABSTRACT We present the first large sample of scintillation arcs in millisecond pulsars (MSPs), analysing 12 sources observed with the Large European Array for…”
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Assessment of the Salinization Process at the Coastal Area with Hydrogeochemical Tools and Geographical Information Systems (GIS): Selçuk Plain, Izmir, Turkey by Somay, Melis A., Gemici, Ünsal

“…The salinization process was investigated with hydrogeochemical tools to evaluate the origin of salinity in the Selçuk Plain. Na/Cl and Cl/Br molar ratios of…”
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Sardinia Radio Telescope wide-band spectral-polarimetric observations of the galaxy cluster 3C 129 by Murgia, M., Govoni, F., Carretti, E., Melis, A., Concu, R., Trois, A., Loi, F., Vacca, V., Tarchi, A., Castangia, P., Possenti, A., Bocchinu, A., Burgay, M., Casu, S., Pellizzoni, A., Pisanu, T., Poddighe, A., Poppi, S., D'Amico, N., Bachetti, M., Corongiu, A., Egron, E., Iacolina, N., Ladu, A., Marongiu, P., Migoni, C., Perrodin, D., Pilia, M., Valente, G., Vargiu, G.

“…We present new observations of the galaxy cluster 3C 129 obtained with the Sardinia Radio Telescope in the frequency range 6000–7200 MHz, with the aim to image…”
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Caregivers in home palliative care: gender, psychological aspects, and patient’s functional status as main predictors for their quality of life by Franchini, L., Ercolani, G., Ostan, R., Raccichini, M., Samolsky-Dekel, A., Malerba, M.B., Melis, A., Varani, S., Pannuti, R.

“…Purpose This study aims to investigate the impact of possible predictors of quality of life (QoL) in a group of Italian caregivers assisting a cancer patient…”
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Genetic variation in severe cystic fibrosis liver disease is associated with novel mechanisms for disease pathogenesis by Stonebraker, Jaclyn R, Pace, Rhonda G, Gallins, Paul J, Dang, Hong, Aksit, Melis A, Faino, Anna V, Gordon, William W, MacParland, Sonya, Bamshad, Michael J, Gibson, Ronald L, Cutting, Garry R, Durie, Peter R, Wright, Fred A, Zhou, Yi-Hui, Blackman, Scott M, O'Neal, Wanda K, Ling, Simon C, Knowles, Michael R

“…It is not known why severe cystic fibrosis (CF) liver disease (CFLD) with portal hypertension occurs in only ~7% of people with CF. We aimed to identify…”
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Improved biomechanical metrics of cerebral vasospasm identified via sensitivity analysis of a 1D cerebral circulation model by Melis, A., Moura, F., Larrabide, I., Janot, K., Clayton, R.H., Narata, A.P., Marzo, A.

“…Cerebral vasospasm (CVS) is a life-threatening condition that occurs in a large proportion of those affected by subarachnoid haemorrhage and stroke. CVS…”
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Complete CFTR gene sequencing in 5,058 individuals with cystic fibrosis informs variant-specific treatment by Raraigh, Karen S, Aksit, Melis A, Hetrick, Kurt, Pace, Rhonda G, Ling, Hua, O'Neal, Wanda, Blue, Elizabeth, Zhou, Yi-Hui, Bamshad, Michael J, Blackman, Scott M, Gibson, Ronald L, Knowles, Michael R, Cutting, Garry R

“…•Full-gene CFTR sequencing identifies CF-causing genotypes in almost all individuals with CF.•Full-gene sequencing can identify gene rearrangements that are…”
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Investigating the high-frequency spectral features of SNRs Tycho, W44, and IC443 with the Sardinia Radio Telescope by Loru, S, Pellizzoni, A, Egron, E, Righini, S, Iacolina, M N, Mulas, S, Cardillo, M, Marongiu, M, Ricci, R, Bachetti, M, Pilia, M, Trois, A, Ingallinera, A, Petruk, O, Murtas, G, Serra, G, Buffa, F, Concu, R, Gaudiomonte, F, Melis, A, Navarrini, A, Perrodin, D, Valente, G

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