Search Results - "MELENDY, T"

An interaction between replication protein A and SV40 T antigen appears essential for primosome assembly during SV40 DNA replication by MELENDY, T, STILLMAN, B

“…Replication protein A from human cells (hRPA) is a multisubunit single-stranded DNA-binding protein (ssb) and is essential for SV40 DNA replication in vitro…”
Get full text

Cellular factors required for papillomavirus DNA replication by Melendy, T, Sedman, J, Stenlund, A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

331 (PB319): A synergistic two-drug therapy selectively targeting DNA repair dysregulation in p53-deficient cancers by Bakin, A., Alruwaili, M., Guo, A., Straubinger, R., Melendy, T., Foster, B., Fountzilas, C.

Get full text

DNA Damage by the Enediyne C-1027 Results in the Inhibition of DNA Replication by Loss of Replication Protein A Function and Activation of DNA-Dependent Protein Kinase by Liu, Jen-Sing, Kuo, Shu-Ru, Yin, Xia, Beerman, Terry A, Melendy, Thomas

“…Treatment of cells with the enediyne C-1027 is highly efficient at inducing single- and double-strand DNA breaks. This agent is highly cytotoxic when used at…”
Get full text

The majority of human replication protein A remains complexed throughout the cell cycle by Loo, Y M, Melendy, T

“…Replication Protein A (RPA), the replicative single-strand DNA binding protein from eukaryotic cells, is a stable heterotrimeric complex consisting of three…”
Get full text

The Cellular Response to DNA Damage Induced by the Enediynes C-1027 and Neocarzinostatin Includes Hyperphosphorylation and Increased Nuclear Retention of Replication Protein A (RPA) and Trans Inhibition of DNA Replication by McHugh, Mary M, Yin, Xia, Kuo, Shu-Ru, Liu, Jen-Sing, Melendy, Thomas, Beerman, Terry A

“…This study examined the cellular response to DNA damage induced by antitumor enediynes C-1027 and neocarzinostatin. Treatment of cells with either agent…”
Get full text

Bleomycin-Induced Alterations in DNA Replication:  Relationship to DNA Damage by Dziegielewski, Jaroslaw, Melendy, Thomas, Beerman, Terry A

“…Bleomycin (BLM), a well-known DNA scission agent, is assumed to inhibit intracellular DNA replication by damaging the DNA template (cis-acting mechanism),…”
Get full text

Novobiocin Affinity Purification of a Mitochondrial Type II Topoisomerase from the Trypanosomatid Crithidia fasciculata by Melendy, T, Ray, D S

“…A mitochondrial type II DNA topoisomerase (topoIImt) has been purified to near homogeneity from the trypanosomatid Crithidia fasciculata. A rapid purification…”
Get full text

Purification of DNA polymerase delta as an essential simian virus 40 DNA replication factor by Melendy, T, Stillman, B

“…DNA replication from the SV40 origin can be reconstituted in vitro using purified SV40 large T antigen, cellular topoisomerases I and II, replication factor A…”
Get full text

Conservation of Structure and Function of DNA Replication Protein A in the Trypanosomatid Crithidia fasciculata by Brown, Grant W., Melendy, Thomas E., Ray, Dan S.

“…Human replication protein A (RP-A) is a three-subunit protein that is required for simian virus 40 (SV40) replication in vitro. The trypanosome homologue of…”
Get full text

The DNA-binding domain of simian virus 40 tumor antigen has multiple functions by KYUNGOK WUN-KIM, UPSON, R, YOUNG, W, MELENDY, T, STILLMAN, B, SIMMONS, D. T

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Chromatin remodeling and initiation of DNA replication by Melendy, Thomas

Get full text

Replication of DNA minicircles in kinetoplasts isolated from Crithidia fasciculata: structure of nascent minicircles by SHELINE, C, MELENDY, T, RAY, D. S

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Recruitment of Replication Protein A by the Papillomavirus E1 Protein and Modulation by Single-Stranded DNA by LOO, Yueh-Ming, MELENDY, Thomas

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Papillomavirus E1 Protein Binds to and Stimulates Human Topoisomerase I by CLOWER, Randolph V, FISK, John C, MELENDY, Thomas

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Cellular Topoisomerase I Modulates Origin Binding by Bovine Papillomavirus Type 1 E1 by Hu, Yan, Clower, Randolph V, Melendy, Thomas

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Mcm2, but Not RPA, Is a Component of the Mammalian Early G1-Phase Prereplication Complex by Dimitrova, Daniela S., Todorov, Ivan T., Melendy, Thomas, Gilbert, David M.

“…Previous experiments in Xenopus egg extracts identified what appeared to be two independently assembled prereplication complexes (pre-RCs) for DNA replication:…”
Get full text

Papillomavirus E2 protein interacts with and stimulates human topoisomerase I by Clower, Randolph V., Hu, Yan, Melendy, Thomas

“…The papillomavirus (PV) E2 protein plays a role in recruiting viral and cellular DNA replication factors, such as PV E1 or RPA to PV genomes. Using both…”
Get full text

Phosphorylation of replication protein A by S-phase checkpoint kinases by Liu, Jen-Sing, Kuo, Shu-Ru, Melendy, Thomas

“…The major eukaryotic single-stranded DNA (ssDNA) binding protein, replication protein A (RPA), is a heterotrimer with subunits of 70, 32 and 14 kDa (RPA70,…”
Get full text

Interactions of the cellular CCAAT displacement protein and human papillomavirus E2 protein with the viral origin of replication can regulate DNA replication by Narahari, Janaki, Fisk, John C., Melendy, Thomas, Roman, Ann

“…Previously, we and others have shown that CCAAT displacement protein (CDP) negatively regulates the papillomavirus promoters. Overexpression of CDP has been…”
Get full text