Search Results - "MEIRIGENG QI"
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Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates
Published in Nature materials (01-06-2017)“…Host recognition and immune-mediated foreign body response to biomaterials can compromise the performance of implanted medical devices. To identify key cell…”
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Semi-Automated Assessment of Human Islet Viability Predicts Transplantation Outcomes in a Diabetic Mouse Model
Published in Cell transplantation (01-01-2020)“…In clinical and experimental human pancreatic islet transplantations, establishing pretransplant assessments that accurately predict transplantation outcomes…”
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Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques
Published in Nature biomedical engineering (01-11-2018)“…The transplantation of pancreatic islet cells could restore glycaemic control in patients with type 1 diabetes. Microspheres for islet encapsulation have…”
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A Multiparametric Assessment of Human Islets Predicts Transplant Outcomes in Diabetic Mice
Published in Cell transplantation (2021)“…Prior to transplantation into individuals with type 1 diabetes, in vitro assays are used to evaluate the quality, function and survival of isolated human…”
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Impairment of neurovascular coupling in Type 1 Diabetes Mellitus in rats is prevented by pancreatic islet transplantation and reversed by a semi-selective PKC inhibitor
Published in Brain research (15-01-2017)“…Abstract Streptozotocin (STZ)-induced chronic hyperglycemia has a detrimental effect on neurovascular coupling, linked to increased PKC-mediated…”
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Biological hypoxia in pre-transplant human pancreatic islets induces transplant failure in diabetic mice
Published in Scientific reports (30-05-2024)“…Evaluating the quality of isolated human islets before transplantation is crucial for predicting the success in treating Type 1 diabetes. The current gold…”
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Physiomimetic Fluidic Culture Platform on Microwell-Patterned Porous Collagen Scaffold for Human Pancreatic Islets
Published in Cell transplantation (01-01-2024)“…Pancreatic islet transplantation is one of the clinical options for certain types of diabetes. However, difficulty in maintaining islets prior to…”
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Chronic marijuana usage by human pancreas donors is associated with impaired islet function
Published in PloS one (27-10-2021)“…We investigated the effect of chronic marijuana use, defined as 4 times weekly for more than 3 years, on human pancreatic islets. Pancreata from deceased…”
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Encompassing ATP, DNA, insulin, and protein content for quantification and assessment of human pancreatic islets
Published in Cell and tissue banking (01-03-2018)“…Islet transplantation has made major progress to treat patients with type 1 diabetes. Islet mass and quality are critically important to ensure successful…”
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Pancreatic human islets and insulin-producing cells derived from embryonic stem cells are rapidly identified by a newly developed Dithizone
Published in Scientific reports (26-06-2019)“…We developed an optimized Dipheylthiocarbazone or Dithizone (DTZ) with improved physical and chemical properties to characterize human islets and…”
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Binding and leakage of barium in alginate microbeads
Published in Journal of biomedical materials research. Part A (01-11-2012)“…Microbeads of alginate crosslinked with Ca2+ and/or Ba2+ are popular matrices in cell‐based therapy. The aim of this study was to quantify the binding of…”
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Transplantation of Encapsulated Pancreatic Islets as a Treatment for Patients with Type 1 Diabetes Mellitus
Published in Advances in medicine (01-01-2014)“…Encapsulation of pancreatic islets has been proposed and investigated for over three decades to improve islet transplantation outcomes and to eliminate the…”
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Effect of prolonged gelling time on the intrinsic properties of barium alginate microcapsules and its biocompatibility
Published in Journal of microencapsulation (01-09-2011)“…Pericapsular fibrotic overgrowth (PFO) may be attributed to an immune response against microcapsules themselves or to antigen shedding through microcapsule…”
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15
Reassessing the Abundance of miRNAs in the Human Pancreas and Rodent Cell Lines and Its Implication
Published in Non-coding RNA (17-03-2023)“…miRNAs are critical for pancreas development and function. However, we found that there are discrepancies regarding pancreatic miRNA abundance in published…”
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Intra-pancreatic tissue-derived mesenchymal stromal cells: a promising therapeutic potential with anti-inflammatory and pro-angiogenic profiles
Published in Stem cell research & therapy (15-11-2019)“…Human pancreata contain many types of cells, such as endocrine islets, acinar, ductal, fat, and mesenchymal stromal cells (MSCs). MSCs are important and shown…”
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Human Pancreatic Islets Isolated From Donors With Elevated HbA1c Levels: Islet Yield and Graft Efficacy
Published in Cell transplantation (01-09-2015)“…The aim of this study was to investigate the effects of elevated donor HbA1c levels (type 2 diabetes, T2D) on the islet yield and functionality postisolation…”
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Improved human pancreatic islet purification with the refined UIC-UB density gradient
Published in Transplantation (15-11-2007)“…Human islet isolation outcomes were compared between two purification methods; 32 pancreases were processed by conventional Biocoll purification method (SM,…”
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Histidine-tryptophan-ketoglutarate and University of Wisconsin solution demonstrate equal effectiveness in the preservation of human pancreata intended for islet isolation: a large-scale, single-center experience
Published in Cell transplantation (01-07-2013)“…We previously reported a small-scale study on the efficacy of histidine-tryptophan-ketoglutarate (HTK) solution versus University of Wisconsin (UW) solution on…”
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Diazoxide, a K(ATP) channel opener, prevents ischemia-reperfusion injury in rodent pancreatic islets
Published in Cell transplantation (2015)“…Diazoxide (DZ) is a pharmacological opener of ATP-sensitive K(+) channels that has been used for mimicking ischemic preconditioning and shows protection…”
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