Search Results - "MEHREGAN, Aujan"

Ca2+ Signaling and Homeostasis in Mammalian Oocytes and Eggs by Wakai, Takuya, Mehregan, Aujan, Fissore, Rafael A

“…Changes in the intracellular concentration of calcium ([Ca2+]i) represent a vital signaling mechanism enabling communication between and among cells as well as…”
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The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors by Nys, Mieke, Zarkadas, Eleftherios, Brams, Marijke, Mehregan, Aujan, Kambara, Kumiko, Kool, Jeroen, Casewell, Nicholas R., Bertrand, Daniel, Baenziger, John E., Nury, Hugues, Ulens, Chris

“…Bites by elapid snakes (e.g. cobras) can result in life-threatening paralysis caused by venom neurotoxins blocking neuromuscular nicotinic acetylcholine…”
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Author Correction: The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors by Nys, Mieke, Zarkadas, Eleftherios, Brams, Marijke, Mehregan, Aujan, Kambara, Kumiko, Kool, Jeroen, Casewell, Nicholas R., Bertrand, Daniel, Baenziger, John E., Nury, Hugues, Ulens, Chris

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TRPM7 and CaV3.2 channels mediate Ca2+ influx required for egg activation at fertilization by Bernhardt, Miranda L., Stein, Paula, Carvacho, Ingrid, Krapp, Christopher, Ardestani, Goli, Mehregan, Aujan, Umbach, David M., Bartolomei, Marisa S., Fissore, Rafael A., Williams, Carmen J.

“…The success of mammalian development following fertilization depends on a series of transient increases in egg cytoplasmic Ca2+, referred to as Ca2+…”
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Clinical and molecular characteristics of a novel rare de novo variant in PPP2CA in a patient with a developmental disorder, autism, and epilepsy by Verbinnen, Iris, Procknow, Sara S, Lenaerts, Lisa, Reynhout, Sara, Mehregan, Aujan, Ulens, Chris, Janssens, Veerle, King, Katherine A

“…PP2A-related (neuro) developmental disorders are a family of genetic diseases caused by a heterozygous alteration in one of several genes encoding a subunit of…”
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Spicy Science: Structural snapshots of a polymodal nociceptor reveal insights on our sensation to pain, heat, and taste by Mehregan, Aujan, Ulens, Chris

“…•Structural snapshots of TRPV1 reveal detailed gating mechanisms.•Structural substates resolved using cryo-electron microscopy.•TRPV1 upper and lower gates…”
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Deletion of TRPV3 and CaV3.2 T-type channels in mice undermines fertility and Ca2+ homeostasis in oocytes and eggs by Mehregan, Aujan, Ardestani, Goli, Akizawa, Hiroki, Carvacho, Ingrid, Fissore, Rafael

“…Ca 2+ influx during oocyte maturation and after sperm entry is necessary to fill the internal Ca 2+ stores and for complete egg activation. We knocked out the…”
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Deletion of TRPV3 and CaV3.2 T-type channels in mice undermines fertility and Ca2+ homeostasis in oocytes and eggs by Mehregan, Aujan, Ardestani, Goli, Akizawa, Hiroki, Carvacho, Ingrid, Fissore, Rafael

“…Ca2+ influx during oocyte maturation and after sperm entry is necessary to fill the internal Ca2+ stores and for complete egg activation. We knocked out the…”
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Characterizing the interaction of the consensus short-chain neurotoxin, ScNtx, with nicotinic acetylcholine receptors by Mehregan, Aujan, Nys, Mieke, Brams, Marijke, Kambara, Kumiko, Bertrand, Daniel, Ulens, Chris

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Ca 2+ Signaling and Homeostasis in Mammalian Oocytes and Eggs by Wakai, Takuya, Mehregan, Aujan, Fissore, Rafael A

“…Changes in the intracellular concentration of calcium ([Ca ] ) represent a vital signaling mechanism enabling communication between and among cells as well as…”
Get full text

The molecular mechanism of snake short-chain alpha-neurotoxin binding to muscle-type nicotinic acetylcholine receptors by Nys, Mieke, Zarkadas, Eleftherios, Brams, Marijke, Mehregan, Aujan, Kambara, Kumiko, Kool, Jeroen, Casewell, Nicholas, Bertrand, Daniel, Baenziger, John E., Nury, Hugues, Ulens, Chris

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Divalent cation influx and calcium homeostasis in germinal vesicle mouse oocytes by Ardestani, Goli, Mehregan, Aujan, Fleig, Andrea, Horgen, F. David, Carvacho, Ingrid, Fissore, Rafael A.

“…[Display omitted] •CaV3.2, TRPM7 and TRPV3 channels differentially mediate the influx of Ca2+ and other divalent cations in GV oocytes.•CaV3.2 and TRPM7 are…”
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Impaired Cerebral Autoregulation Is Associated With Vasospasm and Delayed Cerebral Ischemia in Subarachnoid Hemorrhage by OTITE, Fadar, MINK, Susanne, SOROND, Farzaneh A, CAN OZAN TAN, PURI, Ajit, ZAMANI, Amir A, MEHREGAN, Aujan, CHOU, Sherry, ORZELL, Susannah, PURKAYASTHA, Sushmita, DU, Rose

“…Cerebral autoregulation may be impaired in the early days after subarachnoid hemorrhage (SAH). The purpose of this study was to examine the relationship…”
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Regulation of a pentameric ligand-gated ion channel by a semiconserved cationic lipid-binding site by Sridhar, Akshay, Lummis, Sarah C.R., Pasini, Diletta, Mehregan, Aujan, Brams, Marijke, Kambara, Kumiko, Bertrand, Daniel, Lindahl, Erik, Howard, Rebecca J., Ulens, Chris

“…Pentameric ligand-gated ion channels (pLGICs) are crucial mediators of electrochemical signal transduction in various organisms from bacteria to humans. Lipids…”
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The Molecular Recognition Of The Insecticide Sulfoxaflor By Nicotinic Receptors Is Based On Atomic Interactions Identical To Bee‐Harming Neonicotinoids by Ulens, Chris, Bisseling, Quinty, Brams, Marijke, Mehregan, Aujan, Evans, Genevieve, Pasini, Diletta, Gruss, Fabian

“…Neonicotinoids, sometimes called ‘neonics’, are a class of insecticides targeting neuronal nicotinic acetylcholine receptors, which belong to the family of…”
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Impaired Cerebrovascular Hemodynamics are Associated with Cerebral White Matter Damage by Purkayastha, Sushmita, Fadar, Otite, Mehregan, Aujan, Salat, David H, Moscufo, Nicola, Meier, Dominik S, Guttmann, Charles RG, Fisher, Naomi DL, Lipsitz, Lewis A, Sorond, Farzaneh A

“…White matter hyperintensities (WMH) in elderly individuals with vascular diseases are presumed to be due to ischemic small vessel diseases; however, their…”
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Molecular Recognition of Neonicotinoid Insecticides by Honeybee Nicotinic Receptors and ACHBP Homologues by Ulens, Chris, Bisseling, Quinty, Brams, Marijke, Mehregan, Aujan, Evans, Genevieve L., Pasini, Diletta, Beard, Hester, Verhelst, Steven, Fish, Alexander, van Dorst, Sofie, Kambara, Kumiko, Bertrand, Daniel

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TRPM7 and Ca^sub V^3.2 channels mediate Ca^sup 2+^ influx required for egg activation at fertilization by Bernhardt, Miranda L, Stein, Paula, Carvacho, Ingrid, Krapp, Christopher, Ardestani, Goli, Mehregan, Aujan, Umbach, David M, Bartolomei, Marisa S, Fissore, Rafael A, Williams, Carmen J

“…The success of mammalian development following fertilization depends on a series of transient increases in egg cytoplasmic Ca2+, referred to as Ca2+…”
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TRPM7 and Ca V 3.2 channels mediate Ca 2+ influx required for egg activation at fertilization by Bernhardt, Miranda L, Stein, Paula, Carvacho, Ingrid, Krapp, Christopher, Ardestani, Goli, Mehregan, Aujan, Umbach, David M, Bartolomei, Marisa S, Fissore, Rafael A, Williams, Carmen J

“…The success of mammalian development following fertilization depends on a series of transient increases in egg cytoplasmic Ca , referred to as Ca oscillations…”
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Association between Cerebral tissue Structural Integrity and Dynamic Cerebral Autoregulation in Elderly Individuals by Purkayastha, Sushmita, Fadar, Otite, Mehregan, Aujan, Lipsitz, Lewis A, Sorond, Farzaneh A

“…Abstract only Objective Cerebral white matter hyperintensity (WMH) is prevalent in the elderly population and is associated with hypoperfusion and ischemia…”
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