Search Results - "MEEHAN, K. R"

Treatment of multiple myeloma with adoptively transferred chimeric NKG2D receptor-expressing T cells by Barber, A, Meehan, K R, Sentman, C L

“…Multiple myeloma causes approximately 10% of all hematologic malignancies. We have previously shown that human T cells expressing chimeric NKG2D receptors…”
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Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus by Todo, T, Rabkin, S D, Sundaresan, P, Wu, A, Meehan, K R, Herscowitz, H B, Martuza, R L

“…Replication-competent, attenuated herpes simplex virus (HSV) vectors have been developed for viral oncolytic therapy of primary and metastatic malignant brain…”
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Access to bone marrow transplantation for leukemia and lymphoma: the role of sociodemographic factors by Mitchell, J M, Meehan, K R, Kong, J, Schulman, K A

“…Use of bone marrow transplantation (BMT), a complex, costly treatment for many forms of cancers, has increased significantly in recent years. The increasingly…”
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Platelet transfusions: Utilization and associated costs in a tertiary care hospital by Meehan, K.R., Matias, C.O., Rathore, S.S., Sandler, S.G., Kallich, J., LaBrecque, J., Erder, H., Schulman, K.A.

“…We implemented a prospective study to evaluate platelet transfusion utilization, resource use, and costs in a tertiary care hospital over a 6‐month period. All…”
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Early recovery of aggressive cytotoxic cells and improved immune resurgence with post-transplant immunotherapy for multiple myeloma by MEEHAN, K. R, WU, J, BENGTSON, E, HILL, J, ELY, P, SZCZEPIORKOWSKI, Z, KENDALL, M, ERNSTOFF, M. S

“…A phase I/II trial evaluated early administration and dose escalation of interleukin (IL)-2 with granulocyte macrophage colony stimulating factor (GM-CSF)…”
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Immunotherapy with interleukin-2 and α-interferon after IL-2-activated hematopoietic stem cell transplantation for breast cancer by MEEHAN, K. R, ARUN, B, GEHAN, E. A, BERBERIAN, B, SULICA, V, AREMAN, E. M, MAZUMDER, A, LIPPMAN, M. E

“…We previously demonstrated findings suggestive of autologous GVHD in patients receiving IL-2-activated peripheral blood stem cells (PBSC) with IL-2 after…”
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Interleukin-2-activated hematopoietic stem cell transplantation for breast cancer : Investigation of dose level with clinical correlates by MEEHAN, K. R, VERMA, U. N, MAZUMDER, A, CAHILL, R, FRANKEL, S, AREMAN, E. M, SACHER, R. A, FOELBER, R, RAJAGOPAL, C, GEHAN, E. A, LIPPMAN, M. E

“…Incubating hematopoietic stem cells with IL-2 in vitro for 24 h generates cytotoxic T cells. When infused into patients, these cells may stimulate a…”
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Outcomes of high-dose chemotherapy and autologous stem cell transplant in isolated locally recurrent breast cancer : a multicenter evaluation by VIJ, R, DIPERSIO, J, PONNURI, J, ADKINS, D, BROWN, R, TRINKAUS, K, ABBOUD, C, MEEHAN, K. R, FRENETTE, G, FREYTES, C, GOODNOUGH, L. T, KHOURY, H

“…To determine the outcomes of women with isolated loco-regional recurrence (LRR) of breast cancer treated with high-dose chemotherapy (HDCT) and autologous stem…”
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Analysis and characterization of hematopoietic progenitor cells from fetal bone marrow, adult bone marrow, peripheral blood, and cord blood by AI GUO WU, MICHEJDA, M, MAZUMDER, A, MEEHAN, K. R, MENENDEZ, F. A, TCHABO, J.-G, SLACK, R, JOHNSON, M. P, BELLANTI, J. A

“…Hematopoietic stem cell transplantation has been increasingly used to replace a defective hematopoietic system and to treat various genetic defects as well as…”
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Idiopathic giant cell myocarditis after autologous hematopoietic stem cell transplantation and interleukin-2 immunotherapy : A case report by TRUICA, C. I, HANSEN, C. H, GARVIN, D. F, MEEHAN, K. R

“…Interleukin-2 (IL-2) is used in the treatment of solid tumors and hematologic malignancies. Sudden death is a rare complication of IL-2 treatment. A patient…”
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Development of a clinical model for ex vivo expansion of multiple populations of effector cells for adoptive cellular therapy by Meehan, K.R, MD, Wu, J, Ernstoff, M.S, Webber, S.M, Barber, A, Szczepiorkowski, Z.M, Sentman, C

“…Background We have previously demonstrated a laboratory model for expanding autologous mononuclear cells into populations of effector killer cells. The goal of…”
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Suppression of progenitor cell growth by vancomycin following autologous stem cell transplantation by MEEHAN, K. R, VERMA, U. N, ESTEVA-LORENZO, F, MAZUMDER, A

“…The occurrence of hematologic side-effects resulting from the use of vancomycin is rare. Prior to this report, vancomycin-induced neutropenia was believed to…”
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Allogeneic bone marrow transplantation in a patient with hypereosinophilic syndrome by Esteva‐Lorenzo, Francisco J., Meehan, Kenneth R., Spitzer, Thomas R., Mazumder, Amitabha

“…We describe a 32‐year‐old man with idiopathic hypereosinophilic syndrome (HES) who presented with pulmonary dysfunction, thrombocytopenia, lymphadenopathy, and…”
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Preapheresis levels of peripheral blood CD34+ cells correlate with CD34+ peripheral blood progenitor cells in autologous patients by Areman, Ellen M., Meehan, Kenneth R., Sacher, Ronald A.

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Hematopoietic potential of IL-2-cultured peripheral blood stem cells from breast cancer patients by Areman, E M, Mazumder, A, Kotula, P L, Verma, U N, Rajagopal, C, Hancock, S, Guevarra, C, Djahanmir, M, Sacher, R A, Meehan, K R

“…Patients receiving autologous transplants for various malignancies generally experience an increased incidence of relapse compared with patients receiving…”
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Prudent strategies for elective red blood cell transfusion by Welch, H G, Meehan, K R, Goodnough, L T

“…To review the literature on the appropriateness of red blood cell transfusion and current physician practice, with emphasis on the physiologic and symptomatic…”
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Autologous bone marrow transplantation versus chemotherapy in relapsed/refractory non-Hodgkin's lymphoma: estimates of long-term survival from the recent literature by Meehan, K R, Pritchard, R S, Leichter, J W, Littenberg, B, Welch, H G

“…Long-term survival following chemotherapy or autologous bone marrow transplantation in adults with relapsed/refractory non-Hodgkin's lymphoma was evaluated…”
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Studies of possible mechanisms for the effect of urokinase therapy in small cell carcinoma of the lung by Meehan, K R, Zacharski, L R, Maurer, L H, Howell, A L, Memoli, V A, Rousseau, S M, Hunt, J A, Henkin, J

“…Urokinase-type plasminogen activator has been administered by other investigators to patients with small cell carcinoma of the lung (SCCL) in an attempt to…”
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Pretreatment fibrinogen levels are associated with response to chemotherapy in patients with small cell carcinoma of the lung: Department of Veterans Affairs Cooperative Study 188 by Meehan, K R, Zacharski, L R, Moritz, T E, Rickles, F R

“…Small cell carcinoma of the lung (SCCL) responds commonly to combination chemotherapy but resistance to therapy follows. Prior reports have suggested that a…”
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Survival after autologous hematopoietic stem cell transplantation for patients with inflammatory breast carcinoma by Arun, Banu, Slack, Rebecca, Gehan, Edmund, Spitzer, Thomas, Meehan, Kenneth R.

“…BACKGROUND The authors retrospectively determined the clinical outcome of patients with inflammatory breast carcinoma (IBC) treated with high dose chemotherapy…”
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