Search Results - "MEAD, Jonathan N"

SM16, an Orally Active TGF-β Type I Receptor Inhibitor Prevents Myofibroblast Induction and Vascular Fibrosis in the Rat Carotid Injury Model by Fu, Kai, Corbley, Michael J, Sun, Lihong, Friedman, Jessica E, Shan, Feng, Papadatos, James L, Costa, Donald, Lutterodt, Frank, Sweigard, Harry, Bowes, Scott, Choi, Michael, Boriack-Sjodin, P Ann, Arduini, Robert M, Sun, Dongyu, Newman, Miki N, Zhang, Xiamei, Mead, Jonathan N, Chuaqui, Claudio E, Cheung, H-Kam, Zhang, Xin, Cornebise, Mark, Carter, Mary Beth, Josiah, Serene, Singh, Juswinder, Lee, Wen-Cherng, Gill, Alan, Ling, Leona E

“…OBJECTIVE—TGF-β plays a significant role in vascular injury-induced stenosis. This study evaluates the efficacy of a novel, small molecule inhibitor of…”
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Successful shape-based virtual screening: The discovery of a potent inhibitor of the type I TGFβ receptor kinase (TβRI) by JUSWINDER SINGH, CHUAQUI, Claudio E, PAPADATOS, James L, BOWES, Scott, JOSIAH, Serene, LING, Leona E, BORIACK-SJODIN, P. Ann, LEE, Wen-Cherng, PONTZ, Timothy, CORBLEY, Michael J, CHEUNG, H.-Kam, ARDUINI, Robert M, MEAD, Jonathan N, NEWMAN, Miki N

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Target cells promote the development and functional maturation of neurons derived from a sympathetic precursor cell line by Bharmal, S, Slonimsky, J D, Mead, J N, Sampson, C P, Tolkovsky, A M, Yang, B, Bargman, R, Birren, S J

“…The role of target interactions in the development and functional maturation of peripheral neurons was investigated using an immortalized sympathetic precursor…”
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Corrigendum to “Successful shape-based virtual screening: the discovery of a potent inhibitor of the type I TGFβ receptor kinase (TβRI)”: [Bioorg. Med. Chem. Lett. 13 (2003) 4355] by Singh, Juswinder, Chuaqui, Claudio E., Ann Boriack-Sjodin, P., Lee, Wen-Cherng, Pontz, Timothy, Corbley, Michael J., Cheung, H.-Kam, Arduini, Robert M., Mead, Jonathan N., Newman, Miki N., Papadatos, James L., Bowes, Scott, Josiah, Serene, Ling, Leona E.

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Successful shape-based virtual screening: the discovery of a potent inhibitor of the type I TGFbeta receptor kinase (TbetaRI) by Singh, Juswinder, Chuaqui, Claudio E, Boriack-Sjodin, P Ann, Lee, Wen Cherng, Pontz, Timothy, Corbley, Michael J, Cheung, H-Kam, Arduini, Robert M, Mead, Jonathan N, Newman, Miki N, Papadatos, James L, Bowes, Scott, Josiah, Serene, Ling, Leona E

“…We describe the discovery, using shape-based virtual screening, of a potent, ATP site-directed inhibitor of the TbetaRI kinase, an important and novel drug…”
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Nerve growth factor collaborates with myocyte‐derived factors to promote development of presynaptic sites in cultured sympathetic neurons by Lockhart, Sybil T., Mead, Jonathan N., Pisano, Jessica M., Slonimsky, John D., Susan J. Birren

“…Nerve growth factor (NGF) acutely modulates synaptic transmission between sympathetic neurons and their cardiac myocyte targets. NGF also has developmental…”
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