Search Results - "MCRAE, THOMAS"

Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial by Anthenelli, Robert M, Prof, Benowitz, Neal L, Prof, West, Robert, Prof, St Aubin, Lisa, DVM, McRae, Thomas, MD, Lawrence, David, PhD, Ascher, John, MD, Russ, Cristina, MD, Krishen, Alok, MS, Evins, A Eden, Prof

“…Summary Background Substantial concerns have been raised about the neuropsychiatric safety of the smoking cessation medications varenicline and bupropion…”
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Efficacy and safety of dapagliflozin in acute heart failure: Rationale and design of the DICTATE-AHF trial by Cox, Zachary L, Collins, Sean P, Aaron, Mark, Hernandez, Gabriel A, III, A Thomas McRae, Davidson, Beth T, Fowler, Mike, Lindsell, Christopher J, Jr, Frank E Harrell, Jenkins, Cathy A, Kampe, Christina, Miller, Karen F, Stubblefield, William B, Lindenfeld, JoAnn

“…Dapagliflozin, a sodium-glucose cotransporter-2 inhibitor, reduces cardiovascular death and worsening heart failure in patients with chronic heart failure and…”
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Effect of Varenicline on Smoking Cessation Through Smoking Reduction: A Randomized Clinical Trial by Ebbert, Jon O, Hughes, John R, West, Robert J, Rennard, Stephen I, Russ, Cristina, McRae, Thomas D, Treadow, Joan, Yu, Ching-Ray, Dutro, Michael P, Park, Peter W

“…IMPORTANCE: Some cigarette smokers may not be ready to quit immediately but may be willing to reduce cigarette consumption with the goal of quitting…”
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The mortality burden of cachexia or weight loss in patients with colorectal or pancreatic cancer: A systematic literature review by Dunne, Richard F., Crawford, Jeffrey, Smoyer, Karen E., McRae, Thomas D., Rossulek, Michelle I., Revkin, James H., Tarasenko, Lisa C., Bonomi, Philip D.

“…Cancer‐associated cachexia is a multifactorial wasting disorder characterized by anorexia, unintentional weight loss (skeletal muscle mass with or without loss…”
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Mortality burden of pre‐treatment weight loss in patients with non‐small‐cell lung cancer: A systematic literature review and meta‐analysis by Bonomi, Philip D., Crawford, Jeffrey, Dunne, Richard F., Roeland, Eric J., Smoyer, Karen E., Siddiqui, Mohd Kashif, McRae, Thomas D., Rossulek, Michelle I., Revkin, James H., Tarasenko, Lisa C.

“…Cachexia, with weight loss (WL) as a major component, is highly prevalent in patients with cancer and indicates a poor prognosis. The primary objective of this…”
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Efficacy and Safety of Dapagliflozin in Patients With Acute Heart Failure by Cox, Zachary L., Collins, Sean P., Hernandez, Gabriel A., McRae, A. Thomas, Davidson, Beth T., Adams, Kirkwood, Aaron, Mark, Cunningham, Luke, Jenkins, Cathy A., Lindsell, Christopher J., Harrell, Frank E., Kampe, Christina, Miller, Karen F., Stubblefield, William B., Lindenfeld, JoAnn

“…The primary goals during acute heart failure (AHF) hospitalization are decongestion and guideline-directed medical therapy (GDMT) optimization. Unlike…”
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Do tobacco regulatory and economic factors influence smoking cessation outcomes? A post-hoc analysis of the multinational EAGLES randomised controlled trial by Daniel, Belinda, Lawrence, David E, McKenna, Benjamin S, Saccone, Phillip, McRae, Thomas, Evins, A Eden, Anthenelli, Robert M

“…IntroductionWe previously reported global regional differences in smoking cessation outcomes, with smokers of US origin having lower quit rates than smokers…”
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Improved Outcomes Associated with the use of Shock Protocols: Updates from the National Cardiogenic Shock Initiative by Basir, Mir B., Kapur, Navin K., Patel, Kirit, Salam, Murad A., Schreiber, Theodore, Kaki, Amir, Hanson, Ivan, Almany, Steve, Timmis, Steve, Dixon, Simon, Kolski, Brian, Todd, Josh, Senter, Shaun, Marso, Steven, Lasorda, David, Wilkins, Charles, Lalonde, Thomas, Attallah, Antonious, Larkin, Timothy, Dupont, Allison, Marshall, Jeffrey, Patel, Nainesh, Overly, Tjuan, Green, Michael, Tehrani, Behnam, Truesdell, Alexander G., Sharma, Rahul, Akhtar, Yasir, McRae, Thomas, O'Neill, Brian, Finley, John, Rahman, Ayaz, Foster, Malcolm, Askari, Raza, Goldsweig, Andrew, Martin, Scott, Bharadwaj, Aditya, Khuddus, Matheen, Caputo, Christopher, Korpas, Denes, Cawich, Ian, McAllister, David, Blank, Nimrod, Alraies, M. Chadi, Fisher, Ruth, Khandelwal, Akshay, Alaswad, Khaldoon, Lemor, Alejandro, Johnson, Tyrell, Hacala, Michael, O'Neill, William W.

“…Background The National Cardiogenic Shock Initiative is a single‐arm, prospective, multicenter study to assess outcomes associated with early mechanical…”
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Early Utilization of Mechanical Circulatory Support in Acute Myocardial Infarction Complicated by Cardiogenic Shock: The National Cardiogenic Shock Initiative by Basir, Mir B, Lemor, Alejandro, Gorgis, Sarah, Patel, Kirit C, Kolski, Brian C, Bharadwaj, Aditya S, Todd, Joshua W, Tehrani, Behnam N, Truesdell, Alexander G, Lasorda, David M, Lalonde, Thomas A, Kaki, Amir, Schrieber, Theodore L, Patel, Nainesh C, Senter, Shaun R, Gelormini, Joseph L, Marso, Steven P, Rahman, Ayaz M, Federici, Robert E, Wilkins, Charles E, Thomas McRae, 3rd, A, Nsair, Ali, Caputo, Christopher P, Khuddus, Matheen A, Chahin, Juan J, Dupont, Allison G, Goldsweig, Andrew M, Lim, Michael J, Kapur, Navin K, Wohns, David H W, Zhou, Yueren, Hacala, Michael J, O'Neill, William W

“…Acute myocardial infarction complicated by cardiogenic shock (AMI-CS) is associated with significant morbidity and mortality. Mechanical circulatory support…”
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Population pharmacokinetics and exposure–response analyses of varenicline in adolescent smokers by Fediuk, Daryl J., Sweeney, Kevin, Sahasrabudhe, Vaishali, McRae, Thomas, Byon, Wonkyung

“…Varenicline is an approved smoking cessation aid in adults. Population pharmacokinetics (popPK) and exposure–response (ER) (continuous abstinence rates [CAR]…”
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High-dose and low-dose varenicline for smoking cessation in adolescents: a randomised, placebo-controlled trial by Gray, Kevin M, Rubinstein, Mark L, Prochaska, Judith J, DuBrava, Sarah J, Holstein, Ann R, Samuels, Larry, McRae, Thomas D

“…Although cigarette smoking typically begins in adolescence, evidence for successful pharmacological smoking cessation interventions for this population is…”
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Sex effects in predictors of smoking abstinence and neuropsychiatric adverse events in the EAGLES trial by McKee, Sherry A., Lawrence, David E., Saccone, Phillip, McRae, Thomas, Anthenelli, Robert M.

“…•There is limited information regarding sex effects on cessation-related neuropsychiatric adverse events or interactions with psychiatric status.•We conducted…”
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Use of the numerator relationship matrix in genetic analysis of autopolyploid species by Kerr, Richard J., Li, Li, Tier, Bruce, Dutkowski, Gregory W., McRae, Thomas A.

“…Mixed models incorporating the inverse of a numerator relationship matrix (NRM) are widely used to estimate genetic parameters and to predict breeding values…”
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Effect of varenicline for smoking cessation in adolescents - Authors' reply by Gray, Kevin M, Rubinstein, Mark L, Prochaska, Judith J, DuBrava, Sarah J, Holstein, Ann R, Samuels, Larry, McRae, Thomas D

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Effect of a Hospital and Postdischarge Quality Improvement Intervention on Clinical Outcomes and Quality of Care for Patients With Heart Failure With Reduced Ejection Fraction: The CONNECT-HF Randomized Clinical Trial by DeVore, Adam D, Granger, Bradi B, Fonarow, Gregg C, Al-Khalidi, Hussein R, Albert, Nancy M, Lewis, Eldrin F, Butler, Javed, Piña, Ileana L, Allen, Larry A, Yancy, Clyde W, Cooper, Lauren B, Felker, G. Michael, Kaltenbach, Lisa A, McRae, A. Thomas, Lanfear, David E, Harrison, Robert W, Disch, Maghee, Ariely, Dan, Miller, Julie M, Granger, Christopher B, Hernandez, Adrian F

“…IMPORTANCE: Adoption of guideline-directed medical therapy for patients with heart failure is variable. Interventions to improve guideline-directed medical…”
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Effectiveness and Safety of Donepezil in Hispanic Patients with Alzheimer’s Disease: A 12-Week Open-Label Study by Lopez, Oscar L., MD, Mackell, Joan A., PhD, Sun, Yijun, PhD, Kassalow, Laurent M., MS, Xu, Yikang, PhD, McRae, Thomas, MD, Li, Honglan, PhD

“…Background Hispanics represent 10% of the U.S. population and are the fastest growing group. Studies show a higher prevalence and incidence of Alzheimer’s…”
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Care Optimization Through Patient and Hospital Engagement Clinical Trial for Heart Failure: Rationale and design of CONNECT-HF by DeVore, Adam D., Granger, Bradi B., Fonarow, Gregg C., Al-Khalidi, Hussein R., Albert, Nancy M., Lewis, Eldrin F., Butler, Javed, Piña, Ileana L., Heidenreich, Paul A., Allen, Larry A., Yancy, Cyde W., Cooper, Lauren B., Felker, G. Michael, Kaltenbach, Lisa A., McRae, A. Thomas, Lanfear, David E., Harrison, Robert W., Kociol, Robb D., Disch, Maghee, Ariely, Dan, Miller, Julie M., Granger, Christopher B., Hernandez, Adrian F.

“…Many therapies have been shown to improve outcomes for patients with heart failure (HF) in controlled settings, but there are limited data available to inform…”
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Relation Between Previous Lipid-Lowering Therapy and Infarct Size (Creatine Kinase-MB Level) in Patients Presenting With Acute Myocardial Infarction by Aronow, Herbert D., MD, MPH, Lincoff, A. Michael, MD, Quinn, Martin J., MD, PhD, McRae, A. Thomas, MD, Gurm, Hitinder S., MD, Houghtaling, Penny L., MS, Granger, Christopher B., MD, Harrington, Robert A., MD, Van de Werf, Franz, MD, PhD, Topol, Eric J., MD, Lauer, Michael S., MD

“…Animal experimental data have shown that lipid-lowering agents reduce myocardial infarct size. This association has not been well studied in humans. We…”
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Cardiovascular Safety of Varenicline, Bupropion, and Nicotine Patch in Smokers: A Randomized Clinical Trial by Benowitz, Neal L, Pipe, Andrew, West, Robert, Hays, J Taylor, Tonstad, Serena, McRae, Thomas, Lawrence, David, St Aubin, Lisa, Anthenelli, Robert M

“…Quitting smoking is enhanced by the use of pharmacotherapies, but concerns have been raised regarding the cardiovascular safety of such medications. To compare…”
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Varenicline: mode of action, efficacy, safety and accumulated experience salient for clinical populations by Tonstad, Serena, Arons, Cynthia, Rollema, Hans, Berlin, Ivan, Hajek, Peter, Fagerström, Karl, Els, Charl, McRae, Thomas, Russ, Cristina

“…Objective: Varenicline, a selective partial agonist of the α4β2 nicotinic acetylcholine receptor, is a smoking cessation pharmacotherapy that more than doubles…”
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