Search Results - "MCPHERSON, Stuart"
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Evidence of NAFLD progression from steatosis to fibrosing-steatohepatitis using paired biopsies: Implications for prognosis and clinical management
Published in Journal of hepatology (01-05-2015)“…Graphical abstract…”
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Age as a Confounding Factor for the Accurate Non-Invasive Diagnosis of Advanced NAFLD Fibrosis
Published in The American journal of gastroenterology (01-05-2017)“…Non-invasive fibrosis scores are widely used to identify/exclude advanced fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). However, these…”
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Plasma DNA methylation: a potential biomarker for stratification of liver fibrosis in non-alcoholic fatty liver disease
Published in Gut (01-07-2017)“…Liver biopsy is currently the most reliable way of evaluating liver fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). Its inherent risks…”
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What is the impact of a Hepatitis C 'test, trace and treat' pilot using peer workers?
Published in Journal of viral hepatitis (01-12-2023)“…Chronic Hepatitis C virus (HCV) infection is a major cause of morbidity and deaths worldwide. HCV treating teams are working toward the goal of eliminating HCV…”
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Non-alcoholic fatty liver disease: a practical approach to diagnosis and staging
Published in Frontline gastroenterology (01-07-2014)“…Non-alcoholic fatty liver disease (NAFLD) is now the commonest cause of abnormal liver function tests (LFTs) in the UK with approximately a third of the…”
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Summary of the British Transplantation Society UK Guidelines for Hepatitis E and Solid Organ Transplantation
Published in Transplantation (01-01-2018)“…ABSTRACTThe incidence and prevalence of hepatitis E virus (HEV) infection has increased in many developed countries over the last decade, predominantly due to…”
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Using the theoretical domains framework to identify barriers and enabling factors to implementation of guidance for the diagnosis and management of nonalcoholic fatty liver disease: a qualitative study
Published in Translational behavioral medicine (08-10-2020)“…Healthcare professionals and patients highlighted a need to increase knowledge about what NAFLD is and how to manage it through lifestyle behaviour change…”
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Feasibility and acceptability of an evidence-informed digital intervention to support self-management in people with non-alcoholic fatty liver disease: protocol for a non-randomised feasibility study (VITALISE)
Published in Pilot and feasibility studies (19-04-2023)“…Non-alcoholic fatty liver disease (NAFLD) represents a spectrum of disease ranging from simple fatty liver to non-alcoholic steatohepatitis, cirrhosis, liver…”
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A randomised controlled trial of losartan as an anti-fibrotic agent in non-alcoholic steatohepatitis
Published in PloS one (18-04-2017)“…Non-alcoholic fatty liver disease (NAFLD) is a common liver disease worldwide. Experimental and small clinical trials have demonstrated that angiotensin II…”
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Performance of the PRO-C3 collagen neo-epitope biomarker in non-alcoholic fatty liver disease
Published in JHEP reports (01-09-2019)“…There is an unmet need for non-invasive biomarkers in non-alcoholic fatty liver disease (NAFLD) that can diagnose advanced disease and identify patients…”
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Clinical performance of Determine HBsAg 2 rapid test for Hepatitis B detection
Published in Journal of medical virology (01-12-2020)“…Hepatitis B virus (HBV) infection is estimated to affect 292 million people worldwide, 90% of them are unaware of their HBV status. The Determine HBsAg 2…”
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Embedding assessment of liver fibrosis into routine diabetic review in primary care
Published in JHEP reports (01-08-2021)“…Individuals with type 2 diabetes (T2DM) are at high risk of developing non-alcoholic fatty liver disease (NAFLD) and advanced fibrosis/cirrhosis. Screening…”
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Nutrigenetics-based intervention approach for adults with non-alcoholic fatty liver disease (NAFLD): study protocol for a randomised controlled feasibility trial
Published in BMJ open (08-04-2021)“…IntroductionLifestyle interventions targeting weight loss and improved dietary patterns are the recommended treatment for non-alcoholic fatty liver disease…”
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Utility of a buccal swab point-of-care test for the IFNL4 genotype in the era of direct acting antivirals for hepatitis C virus
Published in PloS one (23-01-2023)“…The CC genotype of the IFNL4 gene is known to be associated with increased Hepatitis C (HCV) cure rates with interferon-based therapy and may contribute to…”
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Magnetic resonance imaging and spectroscopy accurately estimate the severity of steatosis provided the stage of fibrosis is considered
Published in Journal of hepatology (01-08-2009)“…Background/Aims Currently the diagnosis and severity of hepatic steatosis can be established accurately only by liver biopsy. Previous small studies found that…”
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Ledipasvir/sofosbuvir and ribavirin for the treatment of ribavirin-refractory persistent hepatitis E virus infection
Published in IDCases (01-01-2023)“…Persistent Hepatitis E Virus infection (HEV) is a rare but increasingly recognised condition in immunocompromised individuals. Untreated, this infection can…”
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Intravenous Immunoglobulin for the Treatment of Severe, Refractory, and Recurrent Clostridium difficile Diarrhea
Published in Diseases of the colon & rectum (01-05-2006)“…PURPOSE:Clostridium difficile diarrhea is common in elderly patients and leads to prolonged hospitalization. Patients with severe or recurrent Clostridium…”
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ASEPTIC: primary antibiotic prophylaxis using co-trimoxazole to prevent SpontanEous bacterial PeritoniTIs in Cirrhosis—study protocol for an interventional randomised controlled trial
Published in Current controlled trials in cardiovascular medicine (27-09-2022)“…Background Bacterial infection is a major cause of mortality in patients with cirrhosis. Spontaneous bacterial peritonitis (SBP) is a serious and common…”
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Practical Diagnosis and Staging of Nonalcoholic Fatty Liver Disease: A Narrative Review
Published in European Medical Journal (Chelmsford, England) (07-06-2018)“…As the rates of obesity increase worldwide, the prevalence of nonalcoholic fatty liver disease (NAFLD) has risen and it is now the most common cause of liver…”
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