Search Results - "MCNICHOLL, Janet"

Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand (the Bangkok Tenofovir Study): a randomised, double-blind, placebo-controlled phase 3 trial by Choopanya, Kachit, MD, Martin, Michael, Dr, Suntharasamai, Pravan, MD, Sangkum, Udomsak, MD, Mock, Philip A, MAppStats, Leethochawalit, Manoj, MD, Chiamwongpaet, Sithisat, MD, Kitisin, Praphan, MD, Natrujirote, Pitinan, MD, Kittimunkong, Somyot, MD, Chuachoowong, Rutt, MD, Gvetadze, Roman J, MD, McNicholl, Janet M, MD, Paxton, Lynn A, MD, Curlin, Marcel E, MD, Hendrix, Craig W, MD, Vanichseni, Suphak, MD

“…Summary Background Antiretroviral pre-exposure prophylaxis reduces sexual transmission of HIV. We assessed whether daily oral use of tenofovir disoproxil…”
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Risk of Nontargeted Infectious Disease Hospitalizations Among US Children Following Inactivated and Live Vaccines, 2005-2014 by Bardenheier, Barbara H., McNeil, Michael M., Wodi, A. Patricia, McNicholl, Janet M., DeStefano, Frank

“…Background. Recent studies have shown that some vaccines have beneficial effects that cannot be explained solely by the prevention of their respective targeted…”
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Broadly neutralizing antibody-mediated protection against simian-HIV infection among macaques with vaginal sexually transmitted infections by Garber, David A., Guenthner, Patricia, Zhao, Chunxia, Mitchell, James, Ellis, Shanon, Jia, Hongwei, Manganare, Marcos, Gazumyan, Anna, Seaman, Michael S., Vishwanathan, Sundaram Ajay, Heneine, Walid, McNicholl, Janet M.

“…Sexually transmitted infections (STIs) increase mucosal HIV infection risk and have the potential to reduce preexposure prophylaxis efficacy. Clinical trials…”
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Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection by Byrareddy, Siddappa N, Kallam, Brianne, Arthos, James, Cicala, Claudia, Nawaz, Fatima, Hiatt, Joseph, Kersh, Ellen N, McNicholl, Janet M, Hanson, Debra, Reimann, Keith A, Brameier, Markus, Walter, Lutz, Rogers, Kenneth, Mayne, Ann E, Dunbar, Paul, Villinger, Tara, Little, Dawn, Parslow, Tristram G, Santangelo, Philip J, Villinger, Francois, Fauci, Anthony S, Ansari, Aftab A

“…Aftab Ansari and his colleagues show that antibody-mediated masking of α4β7 integrin impedes intravaginal transmission of simian immunodeficiency virus in…”
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The predictive value of macaque models of preexposure prophylaxis for HIV prevention by García-Lerma, J. Gerardo, McNicholl, Janet M., Heneine, Walid

“…We review macaque models for preexposure prophylaxis (PrEP) for HIV prevention and highlight their role in advancing currently approved and novel PrEP agents…”
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Combining biomedical preventions for HIV: Vaccines with pre-exposure prophylaxis, microbicides or other HIV preventions by McNicholl, Janet M.

“…Biomedical preventions for HIV, such as vaccines, microbicides or pre-exposure prophylaxis (PrEP) with antiretroviral drugs, can each only partially prevent…”
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Intravaginal ring eluting tenofovir disoproxil fumarate completely protects macaques from multiple vaginal simian-HIV challenges by Smith, James M., Rastogi, Rachna, Teller, Ryan S., Srinivasan, Priya, Mesquita, Pedro M. M., Nagaraja, Umadevi, McNicholl, Janet M., Hendry, R. Michael, Dinh, Chuong T., Martina, Amy, Herold, Betsy C., Kiser, Patrick F.

“…Topical preexposure prophylaxis interrupts HIV transmission at the site of mucosal exposure. Intermittently dosed vaginal gels containing the HIV-1 reverse…”
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The impact of adherence to preexposure prophylaxis on the risk of HIV infection among people who inject drugs by Martin, Michael, Vanichseni, Suphak, Suntharasamai, Pravan, Sangkum, Udomsak, Mock, Philip A, Leethochawalit, Manoj, Chiamwongpaet, Sithisat, Curlin, Marcel E, Na-Pompet, Supawadee, Warapronmongkholkul, Anchalee, Kittimunkong, Somyot, Gvetadze, Roman J, McNicholl, Janet M, Paxton, Lynn A, Choopanya, Kachit

“…To describe participant adherence to daily oral tenofovir in an HIV preexposure prophylaxis (PrEP) trial, examine factors associated with adherence, and assess…”
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Broadly neutralizing antibody-mediated protection of macaques against repeated intravenous exposures to simian-human immunodeficiency virus by Garber, David A., Guenthner, Patricia, Mitchell, James, Ellis, Shanon, Gazumyan, Anna, Nason, Martha, Seaman, Michael S., McNicholl, Janet M., Nussenzweig, Michel C., Heneine, Walid

“…The opioid epidemic has increased parentally acquired HIV infection. To inform the development of a long-acting prevention strategy, we evaluated the…”
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Daily and Nondaily Oral Preexposure Prophylaxis in Men and Transgender Women Who Have Sex With Men: The Human Immunodeficiency Virus Prevention Trials Network 067/ADAPT Study by Grant, Robert M, Mannheimer, Sharon, Hughes, James P, Hirsch-Moverman, Yael, Loquere, Avelino, Chitwarakorn, Anupong, Curlin, Marcel E, Li, Maoji, Amico, K Rivet, Hendrix, Craig W, Anderson, Peter L, Dye, Bonnie J, Marzinke, Mark A, Piwowar-Manning, Estelle, McKinstry, Laura, Elharrar, Vanessa, Stirratt, Michael, Rooney, James F, Eshleman, Susan H, McNicholl, Janet M, van Griensven, Frits, Holtz, Timothy H

“…Nondaily dosing of oral preexposure prophylaxis (PrEP) may provide equivalent coverage of sex events compared with daily dosing. At-risk men and transgender…”
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Topical Delivery of Tenofovir Disoproxil Fumarate and Emtricitabine from Pod-Intravaginal Rings Protects Macaques from Multiple SHIV Exposures by Srinivasan, Priya, Moss, John A, Gunawardana, Manjula, Churchman, Scott A, Yang, Flora, Dinh, Chuong T, Mitchell, James M, Zhang, Jining, Fanter, Rob, Miller, Christine S, Butkyavichene, Irina, McNicholl, Janet M, Smith, Thomas J, Baum, Marc M, Smith, James M

“…Topical preexposure prophylaxis (PrEP) against HIV has been marginally successful in recent clinical trials with low adherence rates being a primary factor for…”
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Sexually transmitted infections and depot medroxyprogesterone acetate do not impact protection from simian HIV acquisition by long-acting cabotegravir in macaques by Vishwanathan, Sundaram Ajay, Zhao, Chunxia, Luthra, Roopa, Khalil, George K., Morris, Monica M., Dinh, Chuong, Gary, Michelle J., Mitchell, James, Spreen, William R., Pereira, Lara E., Heneine, Walid, García-Lerma, J. Gerardo, McNicholl, Janet M.

“…We had previously shown that long-acting cabotegravir (CAB-LA) injections fully protected macaques from vaginal simian HIV (SHIV) infection. Here, we…”
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Assessment of Oral Fluid HIV Test Performance in an HIV Pre-Exposure Prophylaxis Trial in Bangkok, Thailand by Suntharasamai, Pravan, Martin, Michael, Choopanya, Kachit, Vanichseni, Suphak, Sangkum, Udomsak, Tararut, Pairote, Leelawiwat, Wanna, Anekvorapong, Rapeepan, Mock, Philip A, Cherdtrakulkiat, Thitima, Leethochawalit, Manoj, Chiamwongpaet, Sithisat, Gvetadze, Roman J, McNicholl, Janet M, Paxton, Lynn A, Kittimunkong, Somyot, Curlin, Marcel E

“…Rapid easy-to-use HIV tests offer opportunities to increase HIV testing among populations at risk of infection. We used the OraQuick Rapid HIV-1/2 antibody…”
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Durable protection against repeated penile exposures to simian-human immunodeficiency virus by broadly neutralizing antibodies by Garber, David A., Adams, Debra R., Guenthner, Patricia, Mitchell, James, Kelley, Kristen, Schoofs, Till, Gazumyan, Anna, Nason, Martha, Seaman, Michael S., McNicholl, Janet, Nussenzweig, Michel C., Heneine, Walid

“…Penile acquisition of HIV accounts for most infections among men globally. Nevertheless, candidate HIV interventions for men advance to clinical trials without…”
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High Susceptibility to Repeated, Low-Dose, Vaginal SHIV Exposure Late in the Luteal Phase of the Menstrual Cycle of Pigtail Macaques by Vishwanathan, Sundaram A, Guenthner, Patricia C, Lin, Carol Y, Dobard, Charles, Sharma, Sunita, Adams, Debra R, Otten, Ron A, Heneine, Walid, Hendry, R Michael, McNicholl, Janet M, Kersh, Ellen N

“…Fluctuations in susceptibility to HIV or SHIV during the menstrual cycle are currently not fully documented. To address this, the time point of infection was…”
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Severe Monkeypox in Hospitalized Patients - United States, August 10-October 10, 2022 by Miller, Maureen J, Cash-Goldwasser, Shama, Marx, Grace E, Schrodt, Caroline A, Kimball, Anne, Padgett, Kia, Noe, Rebecca S, McCormick, David W, Wong, Joshua M, Labuda, Sarah M, Borah, Brian F, Zulu, Isaac, Asif, Amimah, Kaur, Gurpreet, McNicholl, Janet M, Kourtis, Athena, Tadros, Andrew, Reagan-Steiner, Sarah, Ritter, Jana M, Yu, Yon, Yu, Patricia, Clinton, Rachel, Parker, Corrine, Click, Eleanor S, Salzer, Johanna S, McCollum, Andrea M, Petersen, Brett, Minhaj, Faisal S, Brown, Ericka, Fischer, Michael P, Atmar, Robert L, DiNardo, Andrew R, Xu, Ya, Brown, Cameron, Goodman, Jerry Clay, Holloman, Ashley, Gallardo, Julia, Siatecka, Hanna, Huffman, Georgia, Powell, John, Alapat, Philip, Sarkar, Pralay, Hanania, Nicola A, Bruck, Or, Brass, Steven D, Mehta, Aneesh, Dretler, Alexandra W, Feldpausch, Amanda, Pavlick, Jessica, Spencer, Hillary, Ghinai, Isaac, Black, Stephanie R, Hernandez-Guarin, Laura N, Won, Sarah Y, Shankaran, Shivanjali, Simms, Andrew T, Alarcón, Jemma, O'Shea, Jesse G, Brooks, John T, McQuiston, Jennifer, Honein, Margaret A, O'Connor, Siobhán M, Chatham-Stephens, Kevin, O'Laughlin, Kevin, Rao, Agam K, Raizes, Elliot, Gold, Jeremy A W, Morris, Sapna Bamrah

“…As of October 21, 2022, a total of 27,884 monkeypox cases (confirmed and probable) have been reported in the United States. Gay, bisexual, and other men who…”
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Safety and Pharmacokinetics of Quick-Dissolving Polymeric Vaginal Films Delivering the Antiretroviral IQP-0528 for Preexposure Prophylaxis by Srinivasan, Priya, Zhang, Jining, Martin, Amy, Kelley, Kristin, McNicholl, Janet M, Buckheit, Jr, Robert W, Smith, James M, Ham, Anthony S

“…For human immunodeficiency virus (HIV) prevention, microbicides or drugs delivered as quick-dissolving films may be more acceptable to women than gels because…”
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Enrollment characteristics and risk behaviors of injection drug users participating in the Bangkok Tenofovir Study, Thailand by Martin, Michael, Vanichseni, Suphak, Suntharasamai, Pravan, Sangkum, Udomsak, Chuachoowong, Rutt, Mock, Philip A, Leethochawalit, Manoj, Chiamwongpaet, Sithisat, Kittimunkong, Somyot, van Griensven, Frits, McNicholl, Janet M, Paxton, Lynn, Choopanya, Kachit

“…The Bangkok Tenofovir Study was launched in 2005 to determine if pre-exposure prophylaxis with tenofovir will reduce the risk of HIV infection among injecting…”
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Risk behaviors and risk factors for HIV infection among participants in the Bangkok tenofovir study, an HIV pre-exposure prophylaxis trial among people who inject drugs by Martin, Michael, Vanichseni, Suphak, Suntharasamai, Pravan, Sangkum, Udomsak, Mock, Philip A, Leethochawalit, Manoj, Chiamwongpaet, Sithisat, Gvetadze, Roman J, Kittimunkong, Somyot, Curlin, Marcel E, Worrajittanon, Dararat, McNicholl, Janet M, Paxton, Lynn A, Choopanya, Kachit

“…HIV spread rapidly among people who inject drugs in Bangkok in the late 1980s. In recent years, changes in drug use and HIV-associated risk behaviors have been…”
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Controlling HIV epidemics among injection drug users: eight years of Cross-Border HIV prevention interventions in Vietnam and China by Hammett, Theodore M, Des Jarlais, Don C, Kling, Ryan, Kieu, Binh Thanh, McNicholl, Janet M, Wasinrapee, Punneeporn, McDougal, J Stephen, Liu, Wei, Chen, Yi, Meng, Donghua, Doan, Ngu, Tho, Huu Nguyen, Quyen, Ngoc Hoang, Tren, Van Hoang

“…HIV in Vietnam and Southern China is driven by injection drug use. We have implemented HIV prevention interventions for IDUs since 2002-2003 in Lang Son and Ha…”
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