Search Results - "MCNATTY, Kenneth P"

The ratio of growth differentiation factor 9: Bone morphogenetic protein 15 mRNA expression is tightly co-regulated and differs between species over a wide range of ovulation rates by Crawford, Janet L., McNatty, Kenneth P.

“…► Expression of GDF9 and BMP15 mRNA were highly correlated within-species. ► Ratios of GDF9:BMP15 mRNA were markedly different between-species. ► Expression…”
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Molecular forms of BMP15 and GDF9 in mammalian species that differ in litter size by Swinerd, Gene W., Alhussini, Abdulaziz A., Sczelecki, Sarah, Heath, Derek, Mueller, Thomas D., McNatty, Kenneth P., Pitman, Janet L.

“…Bone morphogenetic protein (BMP15) and growth differentiation factor (GDF9) are critical for ovarian follicular development and fertility and are associated…”
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Growth differentiation factor 9:bone morphogenetic protein 15 (GDF9:BMP15) synergism and protein heterodimerization by Mottershead, David G, Harrison, Craig A, Mueller, Thomas D, Stanton, Peter G, Gilchrist, Robert B, McNatty, Kenneth P

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Proregion of Mouse BMP15 Regulates the Cooperative Interactions of BMP15 and GDF9 by McIntosh, C. Joy, Lun, Stan, Lawrence, Steve, Western, Andrea H, McNatty, Kenneth P, Juengel, Jennifer L

“…Bone morphogenetic protein 15 (BMP15) and growth and differentiation factor 9 (GDF9) are secreted by the mammalian oocyte and are essential for ovarian…”
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Signalling pathways involved in the cooperative effects of ovine and murine GDF9+BMP15-stimulated thymidine uptake by rat granulosa cells by Reader, Karen L, Heath, Derek A, Lun, Stan, McIntosh, C Joy, Western, Andrea H, Littlejohn, Roger P, McNatty, Kenneth P, Juengel, Jennifer L

“…Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) are oocyte-secreted factors known to be involved in regulating the…”
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Mutations in an oocyte-derived growth factor gene ( BMP15 ) cause increased ovulation rate and infertility in a dosage-sensitive manner by Galloway, Susan M, McNatty, Kenneth P, Cambridge, Lisa M, Laitinen, Mika P.E, Juengel, Jennifer L, Jokiranta, T. Sakari, McLaren, Robert J, Luiro, Kaisu, Dodds, Ken G, Montgomery, Grant W, Beattie, Anne E, Davis, George H, Ritvos, Olli

“…Multiple ovulations are uncommon in humans, cattle and many breeds of sheep. Pituitary gonadotrophins and as yet unidentified ovarian factors precisely…”
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Oocytes in sheep homozygous for a mutation in bone morphogenetic protein receptor 1B express lower mRNA levels of bone morphogenetic protein 15 but not growth differentiation factor 9 by Crawford, Janet L, Heath, Derek A, Reader, Karen L, Quirke, Laurel D, Hudson, Norma L, Juengel, Jennifer L, McNatty, Kenneth P

“…The aim of this study was to test the hypothesis that the high ovulation rate in ewes (BB) homozygous for a mutation in the bone morphogenetic protein receptor…”
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Oestrogen receptor α and β, androgen receptor and progesterone receptor mRNA and protein localisation within the developing ovary and in small growing follicles of sheep by Juengel, Jennifer L, Heath, Derek A, Quirke, Laurel D, McNatty, Kenneth P

“…A first step to elucidating the roles that steroids may play in the processes of ovarian development and early follicular growth is to identify the cell types…”
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Oocyte expression, secretion and somatic cell interaction of mouse bone morphogenetic protein 15 during the peri-ovulatory period by Mester, Brigitta, Ritter, Lesley J, Pitman, Janet L, Bibby, Adrian H, Gilchrist, Robert B, McNatty, Kenneth P, Juengel, Jennifer L, McIntosh, C Joy

“…Bone morphogenetic protein 15 (BMP15) is a key intraovarian growth factor regulating mammalian fertility, yet expression and localisation of different BMP15…”
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Growth Differentiation Factor 9 and Bone Morphogenetic Protein 15 Are Essential for Ovarian Follicular Development in Sheep by JUENGEL, Jennifer L, HUDSON, Norma L, RITVOS, Olli, MCNATTY, Kenneth P, HEATH, Derek A, SMITH, Peter, READER, Karen L, LAWRENCE, Steve B, O'CONNELL, Anne R, LAITINEN, Mika P. E, CRANFIELD, Mark, GROOME, Nigel P

“…The aim of this study was to test the hypothesis that both growth differential factor 9 (GDF9) and bone morphogenetic protein (BMP15; also known as GDF9B) are…”
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Effects of active immunization against growth differentiation factor 9 and/or bone morphogenetic protein 15 on ovarian function in cattle by Juengel, Jennifer L, Hudson, Norma L, Berg, Martin, Hamel, Keith, Smith, Peter, Lawrence, Stephen B, Whiting, Lynda, McNatty, Kenneth P

“…Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) are essential for ovarian follicular growth in sheep, whereas only GDF9 is…”
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The Cooperative Effect of Growth and Differentiation Factor-9 and Bone Morphogenetic Protein (BMP)-15 on Granulosa Cell Function Is Modulated Primarily through BMP Receptor II by Edwards, Sara J, Reader, Karen L, Lun, Stan, Western, Andrea, Lawrence, Steve, McNatty, Kenneth P, Juengel, Jennifer L

“…Growth and differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15, GDF9B) are oocyte-derived proteins essential for the growth and function…”
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Bone morphogenetic protein 15 and growth differentiation factor 9 co-operate to regulate granulosa cell function in ruminants by McNatty, Kenneth P, Juengel, Jennifer L, Reader, Karen L, Lun, Stan, Myllymaa, Samu, Lawrence, Steve B, Western, Andrea, Meerasahib, Mohamed F, Mottershead, David G, Groome, Nigel P, Ritvos, Olli, Laitinen, Mika P E

“…The oocyte-secreted polypeptide growth factors, growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15, also known as GDF9B) have both…”
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Ultrasensitive Colorimetric Detection of 17β-Estradiol: The Effect of Shortening DNA Aptamer Sequences by Alsager, Omar A, Kumar, Shalen, Zhu, Bicheng, Travas-Sejdic, Jadranka, McNatty, Kenneth P, Hodgkiss, Justin M

“…We report a strategy enabling ultrasensitive colorimetric detection of 17β-estradiol (E2) in water and urine samples using DNA aptamer-coated gold…”
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Formation of Ovarian Follicles During Fetal Development in Sheep by SAWYER, Heywood R, SMITH, Peter, HEATH, Derek A, JUENGEL, Jennifer L, WAKEFIELD, St. John, MCNATTY, Kenneth P

“…The origin of follicle (i.e., pregranulosa) cells that become the somatic component of primordial follicles is obscure. In addition, information regarding the…”
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Bone morphogenetic protein 15 and growth differentiation factor 9 co-operate to regulate granulosa cell function by McNatty, Kenneth P, Juengel, Jennifer L, Reader, Karen L, Lun, Stan, Myllymaa, Samu, Lawrence, Steve B, Western, Andrea, Meerasahib, Mohamed F, Mottershead, David G, Groome, Nigel P, Ritvos, Olli, Laitinen, Mika P E

“…The oocyte-secreted polypeptide growth factors, growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15, also known as GDF9B) have both…”
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The Effects of Immunizing Sheep with Different BMP15 or GDF9 Peptide Sequences on Ovarian Follicular Activity and Ovulation Rate by MCNATTY, Kenneth P, HUDSON, Norma L, WHITING, Lynda, READER, Karen L, LUN, Stan, WESTERN, Andrea, HEATH, Derek A, SMITH, Peter, MOORE, Lloyd G, JUENGEL, Jennifer L

“…The aims of these studies were to determine the abilities of antisera against different regions of ovine bone morphogenetic protein 15 (BMP15) and growth…”
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Effects of Immunization Against Bone Morphogenetic Protein 15 and Growth Differentiation Factor 9 on Ovulation Rate, Fertilization, and Pregnancy in Ewes by JUENGEL, Jennifer L, HUDSON, Norma L, WHITING, Lynda, MCNATTY, Kenneth P

“…Immunization of ewes against growth differentiation factor 9 (GDF9) or bone morphogenetic protein 15 (BMP15) can lead to an increased ovulation rate; however,…”
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Gonadotrophin-responsiveness of granulosa cells from bone morphogenetic protein 15 heterozygous mutant sheep by McNatty, Kenneth P, Heath, Derek A, Hudson, Norma L, Lun, Stan, Juengel, Jennifer L, Moore, Lloyd G

“…The aim of this study was to test the hypothesis that the higher ovulation-rate in ewes heterozygous for a mutation in bone morphogenetic protein 15 (BMP15;…”
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The role of bone morphogenetic proteins 2, 4, 6 and 7 during ovarian follicular development in sheep: contrast to rat by Juengel, Jennifer L, Reader, Karen L, Bibby, Adrian H, Lun, Stan, Ross, Ian, Haydon, Lisa J, McNatty, Kenneth P

“…The intraovarian roles of BMP family members such as BMP2, 4, 6 and 7 are not well understood, particularly in species with low ovulation rates such as sheep…”
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