Search Results - "MCLEAN, R. D"

Successful elimination of falciparum malaria following the introduction of community-based health workers in Eastern Myanmar: A retrospective analysis by Zaw, Aye Sandar, Win, Ei Shwe Sin, Yan, Soe Wai, Thein, Kyaw Sithu, Verma, Vasundhara, McLean, Alistair R D, Kyaw, Thar Tun, White, Nicholas J, Smithuis, Frank M

“…Myanmar has a large majority of all malaria in the Greater Mekong Subregion. In the past decade, substantial progress was made in malaria control. The residual…”
Get full text

Malaria elimination in remote communities requires integration of malaria control activities into general health care: an observational study and interrupted time series analysis in Myanmar by McLean, Alistair R D, Wai, Hla Phyo, Thu, Aung Myat, Khant, Zay Soe, Indrasuta, Chanida, Ashley, Elizabeth A, Kyaw, Thar Tun, Day, Nicholas P J, Dondorp, Arjen, White, Nicholas J, Smithuis, Frank M

“…Community health workers (CHWs) can provide diagnosis and treatment of malaria in remote rural areas and are therefore key to the elimination of malaria…”
Get full text

High anaemia and iron deficiency prevalence among pregnant women living in low groundwater iron areas of Bangladesh by Hasan, Mohammed Imrul, Ahmed, Shamim, McLean, Alistair R. D, M Quaiyum Rahman, A, Bhuiyan, Mohammad Saiful Alam, Tipu, S. M. Mulk Uddin, Braat, Sabine, Arifeen, Shams El, Hamadani, Jena D, Pasricha, Sant-Rayn, Davidson, Eliza M

“…Background Anaemia is a significant public health concern in Bangladesh, yet data on the prevalence of anaemia in pregnancy and the contribution of iron…”
Get full text

Systematic review of the scrub typhus treatment landscape: Assessing the feasibility of an individual participant-level data (IPD) platform by Saraswati, Kartika, Maguire, Brittany J, McLean, Alistair R D, Singh-Phulgenda, Sauman, Ngu, Roland C, Newton, Paul N, Day, Nicholas P J, Guérin, Philippe J

“…Scrub typhus is an acute febrile illness caused by intracellular bacteria from the genus Orientia. It is estimated that one billion people are at risk, with…”
Get full text

Reduced risk of placental parasitemia associated with complement fixation on Plasmodium falciparum by antibodies among pregnant women by Opi, D. Herbert, Boyle, Michelle J, McLean, Alistair R. D, Reiling, Linda, Chan, Jo-Anne, Stanisic, Danielle I, Ura, Alice, Mueller, Ivo, Fowkes, Freya J. I, Rogerson, Stephen J, Beeson, James G

“…Background The pathogenesis of malaria in pregnancy (MiP) involves accumulation of P. falciparum-infected red blood cells (pRBCs) in the placenta, contributing…”
Get full text

Molecular markers of artemisinin resistance during falciparum malaria elimination in Eastern Myanmar by Thu, Aung Myint, Phyo, Aung Pyae, Pateekhum, Chanapat, Rae, Jade D, Landier, Jordi, Parker, Daniel M, Delmas, Gilles, Watthanaworawit, Wanitda, McLean, Alistair R D, Arya, Ann, Reyes, Ann, Li, Xue, Miotto, Olivo, Soe, Kyaw, Ashley, Elizabeth A, Dondorp, Arjen, White, Nicholas J, Day, Nicholas P, Anderson, Tim J C, Imwong, Mallika, Nosten, Francois, Smithuis, Frank

“…Artemisinin resistance in Plasmodium falciparum threatens global malaria elimination efforts. To contain and then eliminate artemisinin resistance in Eastern…”
Get full text

Intermittent screening and treatment for malaria complementary to routine immunisation in the first year of life in Papua, Indonesia: a cluster randomised superiority trial by Poespoprodjo, Jeanne Rini, Hafiidhaturrahmah, Sariyanti, Novita, Indrawanti, Ratni, McLean, Alistair R D, Simpson, Julie A, Kenangalem, Enny, Burdam, Faustina Helena, Noviyanti, Rintis, Trianty, Leily, Fadhilah, Chairunisa, Soenarto, Yati, Price, Ric N

“…In Papua (Indonesia), infants with P. falciparum and/or P. vivax malaria are at risk of severe anaemia and death. We hypothesized that in an area of high…”
Get full text

P. falciparum infection and maternofetal antibody transfer in malaria-endemic settings of varying transmission by McLean, Alistair R D, Stanisic, Danielle, McGready, Rose, Chotivanich, Kesinee, Clapham, Caroline, Baiwog, Francesca, Pimanpanarak, Mupawjay, Siba, Peter, Mueller, Ivo, King, Christopher L, Nosten, François, Beeson, James G, Rogerson, Stephen, Simpson, Julie A, Fowkes, Freya J I

“…During pregnancy, immunoglobulin G (IgG) is transferred from the mother to the fetus, providing protection from disease in early infancy. Plasmodium falciparum…”
Get full text

Ambulatory induction phase treatment of cryptococcal meningitis in HIV integrated primary care clinics, Yangon, Myanmar by Warrell, Clare E, Macrae, Catriona, McLean, Alistair R D, Wilkins, Edmund, Ashley, Elizabeth A, Smithuis, Frank, Tun, Ni Ni

“…Cryptococcal meningitis (CM) is a common HIV-associated opportunistic-infection worldwide. Existing literature focusses on hospital-based outcomes of induction…”
Get full text

Malaria and immunity during pregnancy and postpartum: a tale of two species by McLean, A R D, Ataide, R, Simpson, J A, Beeson, J G, Fowkes, F J I

“…It is well established that pregnant women are at an increased risk of Plasmodium falciparum infection when compared to non-pregnant individuals and limited…”
Get more information

Protocol for a randomised, multicentre, four-arm, double-blinded, placebo-controlled trial to assess the benefits and safety of iron supplementation with malaria chemoprevention to children in Malawi: IRMA trial by Mwangi, Martin N., Mzembe, Glory, Ngwira, Chikondi C., Vokhiwa, Maclean, Kapulula, Mayamiko D., Larson, Leila M., Braat, Sabine, Harding, Rebecca, McLean, Alistair R. D., Hamadani, Jena D., Biggs, Beverley-Ann, Ataíde, Ricardo, Phiri, Kamija S., Pasricha, Sant-Rayn

“…IntroductionApproximately 40% of children aged 6–59 months worldwide are anaemic. Iron-containing multiple micronutrient powders (MNPs) and iron supplements…”
Get full text

High Antibodies to VAR2CSA in Response to Malaria Infection Are Associated With Improved Birthweight in a Longitudinal Study of Pregnant Women by McLean, Alistair R. D., Opi, D. Herbert, Stanisic, Danielle I., Cutts, Julia C., Feng, Gaoqian, Ura, Alice, Mueller, Ivo, Rogerson, Stephen J., Beeson, James G., Fowkes, Freya J. I.

“…IntroductionPregnant women have an increased risk of P. falciparum infection, which is associated with low birth weight and preterm delivery. VAR2CSA, a…”
Get full text

Antibody responses to Plasmodium falciparum and Plasmodium vivax blood-stage and sporozoite antigens in the postpartum period by McLean, Alistair R. D., Boel, Machteld E., McGready, Rose, Ataide, Ricardo, Drew, Damien, Tsuboi, Takafumi, Beeson, James G., Nosten, François, Simpson, Julie A., Fowkes, Freya J. I.

“…During pregnancy a variety of immunological changes occur to accommodate the fetus. It is unknown whether these changes continue to affect humoral immunity…”
Get full text

Definitions matter: Heterogeneity of COVID-19 disease severity criteria and incomplete reporting compromise meta-analysis by Guérin, Philippe J, McLean, Alistair R D, Rashan, Sumayyah, Lawal, AbdulAzeez, Watson, James A, Strub-Wourgaft, Nathalie, White, Nicholas J

“…Therapeutic efficacy in COVID-19 is dependent upon disease severity (treatment effect heterogeneity). Unfortunately, definitions of severity vary widely. This…”
Get full text

Neurobrucellosis: Clinical and Therapeutic Features by McLean, Donald R., Russell, Neville, Khan, M. Yousuf

“…Eighteen patients with neurobrucellosis are described. Eleven patients had meningitis alone or with papilledema, optic neuropathy, or radiculopathy. Four…”
Get full text

A Simulation Model to Investigate the Impact of Cardiovascular Risk in Renal Transplantation by McLean, D.R., Jardine, A.G.

“…Premature cardiovascular (CV) disease is the leading cause of death following renal transplantation and, as a consequence of death with a functioning graft, it…”
Get full text

Serum iron and transferrin saturation variation are circadian regulated and linked to the harmonic circadian oscillations of erythropoiesis and hepatic Tfrc expression in mice by Bennett, Cavan, Pettikiriarachchi, Anne, McLean, Alistair R. D., Harding, Rebecca, Blewitt, Marnie E., Seillet, Cyril, Pasricha, Sant‐Rayn

“…Serum iron has long been thought to exhibit diurnal variation and is subsequently considered an unreliable biomarker of systemic iron status. Circadian…”
Get full text

Mass drug administration for the acceleration of malaria elimination in a region of Myanmar with artemisinin-resistant falciparum malaria: a cluster-randomised trial by McLean, Alistair R D, Indrasuta, Chanida, Khant, Zay Soe, Phyo, Aung Kyaw, Maung, Sai Maung, Heaton, James, Aung, Hein, Aung, Ye, Soe, Kyaw, Swe, Myo Maung Maung, von Seidlein, Lorenz, Tun, Ni Ni, Tun, Kyaw Myo, Day, Nicholas P J, Ashley, Elizabeth A, Hlaing, Thaung, Kyaw, Thar Tun, Dondorp, Arjen M, Imwong, Mallika, White, Nicholas J, Smithuis, Frank M

“…To contain multidrug-resistant Plasmodium falciparum, malaria elimination in the Greater Mekong subregion needs to be accelerated while current antimalarials…”
Get full text

Observational study of adult respiratory infections in primary care clinics in Myanmar: understanding the burden of melioidosis, tuberculosis and other infections not covered by empirical treatment regimes by Warrell, Clare E, Phyo, Aung Pyae, Win, Mo Mo, McLean, Alistair R D, Watthanaworawit, Wanitda, Swe, Myo Maung Maung, Soe, Kyaw, Lin, Htet Naing, Aung, Yee Yee, Ko, Chitmin Ko, Waing, Cho Zin, Linn, Kaung San, Aung, Yadanar Phoo Wai, Aung, Ne Myo, Tun, Ni Ni, Dance, David A B, Smithuis, Frank M, Ashley, Elizabeth A

“…Abstract Background Lower respiratory infections constitute a major disease burden worldwide. Treatment is usually empiric and targeted towards typical…”
Get full text

Transcranial magnetic stimulation in Behçet's disease: a cross-sectional and longitudinal study with 44 patients comparing clinical, neuroradiological, somatosensory and brain-stem auditory evoked potential findings by Stigsby, Bent, Bohlega, Saeed, McLean, Donald R, Al-Kawi, Mohammed Zuheir

“…Objectives: To compare neurological involvement in Behçet's disease as documented by transcranial magnetic stimulation (TMS) with clinical, neuroradiological,…”
Get full text