Search Results - "MCLEAN, J M"

Male quality, signal reliability and female choice: assessing the expectations of inter‐sexual selection by McLEAN, M. J., BISHOP, P. J., NAKAGAWA, S.

“…Numerous models have attempted to explain the evolution of extravagant male ornaments found in many species. Inter‐sexual indicator models postulate that male…”
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Antigen-driven B cell differentiation in vivo by MCHEYZER-WILLIAMS, M. G, MCLEAN, M. J, LALOR, P. A, NOSSAL, G. J. V

“…The secretion of specific antibodies and the development of somatically mutated memory B cells in germinal centers are consequences of T cell-dependent…”
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Gabapentin in the Management of Convulsive Disorders by McLean, Michael J.

“…Gabapentin, in clinical use since 1993, is indicated as an adjunctive antiepileptic drug (AED) for treatment of complex partial seizures, with or without…”
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Clinical pharmacokinetics of gabapentin by MCLEAN, M. J

“…Pharmacokinetic properties are important to consider in evaluating the usefulness of new antiepileptic drugs (AEDs). Gabapentin is a new, water-soluble,…”
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Gabapentin by McLean, M J

“…The amino acid antiepileptic drug (AED) gabapentin (GBP) is indicated for adjunctive use in the treatment of partial seizures with or without becoming…”
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A static magnetic field modulates severity of audiogenic seizures and anticonvulsant effects of phenytoin in DBA/2 mice by McLean, M.J., Engström, S., Holcomb, R.R., Sanchez, D.

“…Rationale: In a search for potential supplements or alternatives to the pharmacological treatment of epilepsy, we examined the effects of static magnetic…”
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Oxcarbazepine: mechanisms of action by McLean, M J, Schmutz, M, Wamil, A W, Olpe, H R, Portet, C, Feldmann, K F

“…The antiepileptic drug (AED) oxcarbazepine (OCBZ) and its rapidly formed 10-monohydroxy metabolite (MHD) protect against electroshock-induced tonic hindlimb…”
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Safety and Tolerability of Gabapentin as Adjunctive Therapy in a Large, Multicenter Study by McLean, Michael J., Morrell, Martha J., Willmore, L. James, Privitera, Michael D., Faught, R. Edward, Holmes, Gregory L., Magnus‐Miller, Leslie, Bernstein, Paula, Rose‐Legatt, Andrea

“…Purpose: To evaluate the tolerability and safety of gabapentin (GBP) as add‐on therapy for seizure control. Methods: Conducted in an outpatient setting and…”
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Oxcarbazepine: preclinical anticonvulsant profile and putative mechanisms of action by Schmutz, M, Brugger, F, Gentsch, C, McLean, M J, Olpe, H R

“…Oxcarbazepine (OCBZ, Trileptal) and its main human monohydroxy metabolite (MHD) protected mice and rats against generalized tonic-clonic seizures induced by…”
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Sodium valproate, but not ethosuximide, produces use- and voltage-dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture by McLean, M J, Macdonald, R L

“…Effects of the anticonvulsant drugs sodium valproate (NaVP) and ethosuximide (ES) on mouse central (spinal cord and cortical) neurons in primary dissociated…”
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Carbamazepine and 10,11-epoxycarbamazepine produce use- and voltage-dependent limitation of rapidly firing action potentials of mouse central neurons in cell culture by McLean, M J, Macdonald, R L

“…Effects of the anticonvulsant, carbamazepine (CBZ), on mouse central neurons in cell culture were examined using intracellular recording techniques. Spinal…”
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Blockade of sensory neuron action potentials by a static magnetic field in the 10 mT range by McLean, M J, Holcomb, R R, Wamil, A W, Pickett, J D, Cavopol, A V

“…To characterize the inhibitory effect of a static magnetic field, action potentials (AP) were elicited by intracellular application of 1 ms depolarizing…”
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Microscale Fracture Toughness of Bismuth Doped Copper Bicrystals Using Double Edge Notched Microtensile Tests by McLean, M. J., Wade, C. A., Watanabe, M., Vinci, R. P.

“…The availability of focused ion beam (FIB) milling, nanoindentation, and microelectromechanical systems (MEMS) based test platforms has enabled small-scale…”
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Regional distribution of protease-resistant prion protein in fatal familial insomnia by Parchi, P, Castellani, R, Cortelli, P, Montagna, P, Chen, S G, Petersen, R B, Manetto, V, Vnencak-Jones, C L, McLean, M J, Sheller, J R

“…Protease-resistant prion protein, total prion protein, and glial fibrillary acidic protein were measured in various brain regions from 9 subjects with fatal…”
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Phenytoin blocks N-methyl-D-aspartate responses of mouse central neurons by Wamil, A W, McLean, M J

“…Intracellularly recorded depolarizing responses of mouse spinal cord neurons in cell culture to N-methyl-D-aspartate (NMDA) applied by pressure ejection at 37…”
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Multiple actions of phenytoin on mouse spinal cord neurons in cell culture by McLean, M J, Macdonald, R L

“…Concentration-dependence of multiple actions of phenytoin (PT) on mouse spinal cord neurons in primary dissociated cell culture was studied using intracellular…”
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An association between lunate morphology and scaphoid–trapezium–trapezoid arthritis by MCLEAN, J. M., TURNER, P. C., BAIN, G. I., REZAIAN, N., FIELD, J., FOGG, Q.

“…The purpose of this study was to determine if an association exists between scaphoid–trapezium–trapezoid arthritis and lunate morphology. Plain neutral…”
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Prophylactic and therapeutic efficacy of memantine against seizures produced by soman in the rat by McLean, M J, Gupta, R C, Dettbarn, W D, Wamil, A W

“…Male Sprague-Dawley rats injected sc with a single sublethal dose of the organophosphate nerve agent, soman (100 micrograms/kg), had motor limbic seizures…”
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Effects of oxcarbazepine and 10-hydroxycarbamazepine on action potential firing and generalized seizures by Wamil, A W, Schmutz, M, Portet, C, Feldmann, K F, McLean, M J

“…The anticonvulsant compound oxcarbazepine and its principal 10-monohydroxy metabolite protected potently against electroshock-induced tonic hindlimb extension…”
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Measurement and analysis of static magnetic fields that block action potentials in cultured neurons by Cavopol, A V, Wamil, A W, Holcomb, R R, McLean, M J

“…To characterize the properties of static magnetic fields on firing of action potentials (AP) by sensory neurons in cell culture, we developed a mathematical…”
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