Search Results - "MCLAREN, E"

Three‐Component Difunctionalization of Cyclohexenyl Triflates: Direct Access to Versatile Cyclohexenes via Cyclohexynes by Cho, Seoyoung, McLaren, E. J., Wang, Qiu

“…Difunctionalization of strained cyclic alkynes presents a powerful strategy to build richly functionalized cyclic alkenes in an expedient fashion. Herein we…”
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T Cell Immunity to Bacterial Pathogens: Mechanisms of Immune Control and Bacterial Evasion by Shepherd, Freya R, McLaren, James E

“…The human body frequently encounters harmful bacterial pathogens and employs immune defense mechanisms designed to counteract such pathogenic assault. In the…”
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Destabilisation of T cell-dependent humoral immunity in sepsis by Davies, Kate, McLaren, James E

“…Sepsis is a heterogeneous condition defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. For some, sepsis…”
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Comparison of the mechanical properties of translucent zirconia and lithium disilicate by Kwon, Sung Joon, Lawson, Nathaniel C., McLaren, Edward E., Nejat, Amir H., Burgess, John O.

“…Three mol% yttria-stabilized tetragonal zirconia polycrystal (3Y-TZP) possesses excellent mechanical properties but is relatively opaque. Five mol%…”
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The effects of medication use in transcranial direct current stimulation: A brief review by McLaren, Molly E., Nissim, Nicole R., Woods, Adam J.

“…There has been increased interest in the potential use of transcranial direct current stimulation (tDCS) as treatment for multiple conditions including…”
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Chemosensory behaviour of juvenile crown-of-thorns sea star ( Acanthaster sp.), attraction to algal and coral food and avoidance of adult conspecifics by Webb, M, Clements, M, Selvakumaraswamy, P, McLaren, E, Byrne, M

“…Intraspecific and habitat-mediated responses to chemical cues play key roles in structuring populations of marine species. We investigated the behaviour of…”
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Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance by Davey, Martin S., Willcox, Carrie R., Joyce, Stephen P., Ladell, Kristin, Kasatskaya, Sofya A., McLaren, James E., Hunter, Stuart, Salim, Mahboob, Mohammed, Fiyaz, Price, David A., Chudakov, Dmitriy M., Willcox, Benjamin E.

“…γδ T cells are considered to be innate-like lymphocytes that respond rapidly to stress without clonal selection and differentiation. Here we use…”
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Chronic Inflammation Permanently Reshapes Tissue-Resident Immunity in Celiac Disease by Mayassi, Toufic, Ladell, Kristin, Gudjonson, Herman, McLaren, James E., Shaw, Dustin G., Tran, Mai T., Rokicka, Jagoda J., Lawrence, Ian, Grenier, Jean-Christophe, van Unen, Vincent, Ciszewski, Cezary, Dimaano, Matthew, Sayegh, Hoda E., Kumar, Vinod, Wijmenga, Cisca, Green, Peter H.R., Gokhale, Ranjana, Jericho, Hilary, Semrad, Carol E., Guandalini, Stefano, Dinner, Aaron R., Kupfer, Sonia S., Reid, Hugh H., Barreiro, Luis B., Rossjohn, Jamie, Price, David A., Jabri, Bana

“…Tissue-resident lymphocytes play a key role in immune surveillance, but it remains unclear how these inherently stable cell populations respond to chronic…”
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EUS-guided portal pressure gradient measurement with a simple novel device: a human pilot study by Huang, Jason Y., FRACP, Samarasena, Jason B., MD, Tsujino, Takeshi, MD, PhD, Lee, John, MD, Hu, Ke-Qin, MD, McLaren, Christine E., PhD, Chen, Wen-Pin, MS, Chang, Kenneth J., MD

“…Background and Aims Portal hypertension (PH) is a serious adverse event of liver cirrhosis. The hepatic venous pressure gradient or portal pressure gradient…”
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CD4+ T Follicular Helper Cells in Human Tonsils and Blood Are Clonally Convergent but Divergent from Non-Tfh CD4+ Cells by Brenna, Elena, Davydov, Alexey N., Ladell, Kristin, McLaren, James E., Bonaiuti, Paolo, Metsger, Maria, Ramsden, James D., Gilbert, Sarah C., Lambe, Teresa, Price, David A., Campion, Suzanne L., Chudakov, Dmitriy M., Borrow, Persephone, McMichael, Andrew J.

“…T follicular helper (Tfh) cells are fundamental for B cell selection and antibody maturation in germinal centers. Circulating Tfh (cTfh) cells constitute a…”
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Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation by Misheva, Mariya, Kotzamanis, Konstantinos, Davies, Luke C., Tyrrell, Victoria J., Rodrigues, Patricia R. S., Benavides, Gloria A., Hinz, Christine, Murphy, Robert C., Kennedy, Paul, Taylor, Philip R., Rosas, Marcela, Jones, Simon A., McLaren, James E., Deshpande, Sumukh, Andrews, Robert, Schebb, Nils Helge, Czubala, Magdalena A., Gurney, Mark, Aldrovandi, Maceler, Meckelmann, Sven W., Ghazal, Peter, Darley-Usmar, Victor, White, Daniel A., O’Donnell, Valerie B.

“…Oxylipins are potent biological mediators requiring strict control, but how they are removed en masse during infection and inflammation is unknown. Here we…”
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Prevalence of iron deficiency in 62,685 women of seven race/ethnicity groups: The HEIRS Study by Barton, James C, Wiener, Howard H, Acton, Ronald T, Adams, Paul C, Eckfeldt, John H, Gordeuk, Victor R, Harris, Emily L, McLaren, Christine E, Harrison, Helen, McLaren, Gordon D, Reboussin, David M

“…Few cross-sectional studies report iron deficiency (ID) prevalence in women of different race/ethnicity and ages in US or Canada. We evaluated screening…”
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A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8+ T Cells by Ladell, Kristin, Hashimoto, Masao, Iglesias, Maria Candela, Wilmann, Pascal G., McLaren, James E., Gras, Stéphanie, Chikata, Takayuki, Kuse, Nozomi, Fastenackels, Solène, Gostick, Emma, Bridgeman, John S., Venturi, Vanessa, Arkoub, Zaïna Aït, Agut, Henri, van Bockel, David J., Almeida, Jorge R., Douek, Daniel C., Meyer, Laurence, Venet, Alain, Takiguchi, Masafumi, Rossjohn, Jamie, Price, David A., Appay, Victor

“…The capacity of the immune system to adapt to rapidly evolving viruses is a primary feature of effective immunity, yet its molecular basis is unclear. Here, we…”
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Three‐Component Difunctionalization of Cyclohexenyl Triflates: Direct Access to Versatile Cyclohexenes via Cyclohexynes by Cho, Seoyoung, McLaren, E. J., Wang, Qiu

“…Difunctionalization of strained cyclic alkynes presents a powerful strategy to build richly functionalized cyclic alkenes in an expedient fashion. Herein we…”
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IL-33 reduces macrophage foam cell formation by McLaren, James E, Michael, Daryn R, Salter, Rebecca C, Ashlin, Tim G, Calder, Claudia J, Miller, Ashley M, Liew, Foo Y, Ramji, Dipak P

“…The development of atherosclerosis, a chronic inflammatory disease characterized by the formation of arterial fibrotic plaques, has been shown to be reduced by…”
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Hepatic Iron Concentration and Total Body Iron Stores in Thalassemia Major by Angelucci, Emanuele, Brittenham, Gary M, McLaren, Christine E, Ripalti, Marta, Baronciani, Donatella, Giardini, Claudio, Galimberti, Maria, Polchi, Paola, Lucarelli, Guido

“…Quantitative studies of iron balance in patients with thalassemia major have been limited by the lack of a method for determining the total amount of stored…”
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Role of dietary polyamines in a phase III clinical trial of difluoromethylornithine (DFMO) and sulindac for prevention of sporadic colorectal adenomas by Raj, K P, Zell, J A, Rock, C L, McLaren, C E, Zoumas-Morse, C, Gerner, E W, Meyskens, F L

“…Background: The polyamine-inhibitory regimen difluoromethylornithine (DFMO)+sulindac has marked efficacy in preventing metachronous colorectal adenomas…”
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A T cell-inducing influenza vaccine for the elderly: safety and immunogenicity of MVA-NP+M1 in adults aged over 50 years by Antrobus, Richard D, Lillie, Patrick J, Berthoud, Tamara K, Spencer, Alexandra J, McLaren, James E, Ladell, Kristin, Lambe, Teresa, Milicic, Anita, Price, David A, Hill, Adrian V S, Gilbert, Sarah C

“…Current influenza vaccines have reduced immunogenicity and are of uncertain efficacy in older adults. We assessed the safety and immunogenicity of MVA-NP+M1, a…”
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Occurrence of alkylphenols and alkylphenol ethoxylates in North Sea sediment samples collected across oil and gas fields by McLaren, Diana E.K., Rawlins, Andrew J.

“…Alkylphenol ethoxylates (APEs) have been used in several offshore oil and gas production applications including as emulsifiers in drilling mud formulations,…”
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Non-invasive Brain Stimulation: Probing Intracortical Circuits and Improving Cognition in the Aging Brain by Gomes-Osman, Joyce, Indahlastari, Aprinda, Fried, Peter J, Cabral, Danylo L F, Rice, Jordyn, Nissim, Nicole R, Aksu, Serkan, McLaren, Molly E, Woods, Adam J

“…The impact of cognitive aging on brain function and structure is complex, and the relationship between aging-related structural changes and cognitive function…”
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