Search Results - "MCKINNEY, C. E"

A new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharks by Greenberg, Andrew S, Avila, David, Hughes, Marianne, Hughes, Austin, McKinney, E. Churchill, Flajnik, Martin F

“…Immunoglobulin and T-cell receptor (TCR) molecules are central to the adaptive immune system. Sequence conservation, similarities in domain structure, and…”
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The Development of Primary and Secondary Lymphoid Tissues in the Nurse Shark Ginglymostoma cirratum: B‐Cell Zones Precede Dendritic Cell Immigration and T‐Cell Zone Formation During Ontogeny of the Spleen by RUMFELT, L. L., McKINNEY, E. C., TAYLOR, E., FLAJNIK, M. F.

“…Secondary lymphoid tissue and immunoglobulin (Ig) production in mammals is not fully developed at birth, requiring time postnatally to attain all features…”
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Strong, constitutive expression of the Arabidopsis ACT2/ACT8 actin subclass in vegetative tissues by An, Yong‐Qiang, McDowell, John M., Huang, Shurong, McKinney, Elizabeth C., Chambliss, Sharon, Meagher, Richard B.

“…Summary Arabidopsis has a complex and ancient actin gene family encoding six divergent subclasses of proteins. One subclass is represented by ACT2 and ACT8 ,…”
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Structure and evolution of the actin gene family in Arabidopsis thaliana by McDowell, J.M. (University of North Carolina, Chapel Hill, NC.), Huang, S, McKinney, E.C, An, Y.Q, Meagher, R.B

“…Higher plants contain families of actin-encoding genes that are divergent and differentially expressed. Progress in understanding the functions and evolution…”
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The Arabidopsis ACT7 Actin Gene Is Expressed in Rapidly Developing Tissues and Responds to Several External Stimuli by McDowell, John M., Yong-qiang An, Huang, Shurong, McKinney, Elizabeth C., Meagher, Richard B.

“…ACT7 encodes one of the six distinct and ancient subclasses of actin protein in the complex Arabidopsis actin gene family. We determined the sequence and…”
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Proteasome, Transporter Associated with Antigen Processing, and Class I Genes in the Nurse Shark Ginglymostoma cirratum: Evidence for a Stable Class I Region and MHC Haplotype Lineages by Ohta, Yuko, McKinney, E. Churchill, Criscitiello, Michael F, Flajnik, Martin F

“…Cartilaginous fish (e.g., sharks) are derived from the oldest vertebrate ancestor having an adaptive immune system, and thus are key models for examining MHC…”
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Isovariant Dynamics Expand and Buffer the Responses of Complex Systems: The Diverse Plant Actin Gene Family by Meagher, Richard B., McKinney, Elizabeth C., Kandasamy, M. K.

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The evolution of new structures: clues from plant cytoskeletal genes by Meagher, Richard B, McKinney, Elizabeth C, Vitale, Angela V

“…How large numbers of genes were recruited simultaneously to build new organ structures is one of the greatest puzzles in evolutionary biology. Here, we present…”
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Members of the Arabidopsis Actin Gene Family Are Widely Dispersed in the Genome by McKinney, E. C, Meagher, R. B

“…Plant genomes are subjected to a variety of DNA turnover mechanisms that are thought to result in rapid expansion and presumable contraction of gene copy…”
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Glucosylsphingosine accumulation in mice and patients with type 2 Gaucher disease begins early in gestation by ORVISKY, E, SIDRANSKY, E, MCKINNEY, C. E, LAMARCA, M. E, SAMIMI, R, KRASNEWICH, D, MARTIN, B. M, GINNS, E. I

“…Gaucher disease, the most common of the sphingolipidoses, results from the inherited deficiency of the enzyme glucocerebrosidase (EC 3.2.1.45). Although type 2…”
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Small Changes in the Regulation of One Arabidopsis Profilin Isovariant, PRF1, Alter Seedling Development by McKinney, Elizabeth Cohen, Kandasamy, Muthugapatti K., Meagher, Richard B.

“…Profilin (PRF) is a low-molecular-weight actin binding protein encoded by a diverse gene family in plants. Arabidopsis PRF1 transcripts are moderately well…”
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Sequence‐based identification of T‐DNA insertion mutations in Arabidopsis: actin mutants act2‐1 and act4‐1 by McKinney, Elizabeth C., Ali, Nazeem, Traut, Alice, Feldmann, Kenneth A., Belostotsky, Dmitry A., McDowell, John M., Meagher, Richard B.

“…Summary A method is presented to facilitate the isolation of mutations in plant genes, which requires knowledge of the target gene or protein sequence, and is…”
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Evolution of the Major Histocompatibility Complex: Isolation of Class II A cDNA Clones from the Cartilaginous Fish by Kasahara, Masanori, Vazquez, Miriam, Sato, Keisuke, McKinney, E. Churchill, Flajnik, Martin F.

“…Along with the T-cell receptor and immunoglobulin, the major histocompatibility complex (MHC) plays a key role in mounting immune responses to foreign antigen…”
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The late pollen‐specific actins in angiosperms by Kandasamy, Muthugapatti K., McKinney, Elizabeth C., Meagher, Richard B.

“…Summary The actin gene family of Arabidopsis has eight functional genes that are grouped into two ancient classes, vegetative and reproductive, and into five…”
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Consequences of β-glucocerebrosidase deficiency in epidermis : ultrastructure and permeability barrier alterations in Gaucher disease by HOLLERAN, W. M, GINNS, E. I, MENON, G. K, GRUNDMAN, J.-U, FARTASCH, M, MCKINNEY, C. E

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IgM-mediated opsonization and cytotoxicity in the shark by McKinney, E. C., Flajnik, Martin F.

“…Two types of cytotoxic reactions have been observed using cells from the nurse shark: spontaneous cytotoxicity mediated by cells of the macrophage lineage and…”
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The Arabidopsis thaliana ACT4/ACT12 actin gene subclass is strongly expressed throughout pollen development by Huang, Shurong, An, Yong‐Qiang, McDowell, John M., McKinney, Elizabeth C., Meagher, Richard B.

“…Plants contain complex actin gene families composed of several diverse and ancient subclasses of genes. One Arabidopsis actin gene subclass represented by the…”
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The evolutionary origin of the major histocompatibility complex: polymorphism of class II alpha chain genes in the cartilaginous fish by Kasahara, M, McKinney, E C, Flajnik, M F, Ishibashi, T

“…T cells recognize antigen (Ag) in the form of peptides bound to the major histocompatibility complex (MHC) molecule. One of the important issues in…”
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Positive correlation between high aryl hydrocarbon hydroxylase activity and primary lung cancer as analyzed in cryopreserved lymphocytes by Kouri, R E, McKinney, C E, Slomiany, D J, Snodgrass, D R, Wray, N P, McLemore, T L

“…Blood samples from closely monitored patients at the Veterans Administration Hospital in Houston, Texas, were collected, coded, and sent to Microbiological…”
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Metaxin, a Gene Contiguous to Both Thrombospondin 3 and Glucocerebrosidase, is Required for Embryonic Development in the Mouse: Implications for Gaucher Disease by Bornstein, Paul, McKinney, Cindy E., LaMarca, Mary E., Winfield, Suzanne, Shingu, Tetsuji, Devarayalu, Sreelekha, Vos, Hans L., Ginns, Edward I.

“…We have identified a murine gene, metaxin, that spans the 6-kb interval separating the glucocerebrosidase gene (GC) from the thrombospondin 3 gene on…”
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