Search Results - "MCKERCHER, S. R"

Turning Blood into Brain: Cells Bearing Neuronal Antigens Generated in Vivo from Bone Marrow by Mezey, Éva, Chandross, Karen J., Harta, Gyöngyi, Maki, Richard A., McKercher, Scott R.

“…Bone marrow stem cells give rise to a variety of hematopoietic lineages and repopulate the blood throughout adult life. We show that, in a strain of mice…”
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Osteopetrosis in mice lacking haematopoietic transcription factor PU.1 by Tondravi, M. M, McKercher, S. R, Anderson, K, Erdmann, J. M, Quiroz, M, Maki, R, Teitelbaum, S. L

“…Osteoclasts are multinucleated cells and the principal resorptive cells of bone. Although osteoclasts are of myeloid origin, the role of haematopoietic…”
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Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities by McKercher, S. R., Torbett, B. E., Anderson, K. L., Henkel, G. W., Vestal, D. J., Baribault, H., Klemsz, M., Feeney, A. J., Wu, G. E., Paige, C. J., Maki, R. A.

“…PU.1 is a member of the ets family of transcription factors and is expressed exclusively in cells of the hematopoietic lineage. Mice homozygous for a…”
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Defective trophoblast function in mice with a targeted mutation of Ets2 by Yamamoto, H, Flannery, M L, Kupriyanov, S, Pearce, J, McKercher, S R, Henkel, G W, Maki, R A, Werb, Z, Oshima, R G

“…Members of the Ets family of transcription factors mediate transcriptional responses of multiple signaling pathways in diverse cell types and organisms…”
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PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity by PONGUBALA, JM. R, SUJATHA NAGULAPALLI, KLEMSZ, M. J, MCKERCHER, S. R, MAKI, R. A, ATCHISON, M. L

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Effect of PU.1 Phosphorylation on Interaction with NF-EM5 and Transcriptional Activation by Jagan M. R. Pongubala, Van Beveren, Charles, Nagulapalli, Sujatha, Klemsz, Michael J., McKercher, Scott R., Maki, Richard A., Atchison, Michael L.

“…PU.1 recruits the binding of a second B cell-restricted nuclear factor, NF-EM5, to a DNA site in the immunoglobulin κ 3′ enhancer. DNA binding by NF-EM5…”
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The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene by Klemsz, M J, McKercher, S R, Celada, A, Van Beveren, C, Maki, R A

“…We have isolated a cDNA clone, PU.1, that codes for a new tissue-specific DNA binding protein. Analysis of the binding site by methylation interference and…”
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PU.1 But Not Ets-2 Is Essential for Macrophage Development From Embryonic Stem Cells by Henkel, Gregory W., McKercher, Scott R., Yamamoto, Hideyuki, Anderson, Karen L., Oshima, Robert G., Maki, Richard A.

“…Transcription factors play an important role choreographing lineage commitment and expansion of blood cells. Nuclear factors that are expressed primarily or…”
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Mesenchymal cells engulf and clear apoptotic footplate cells in macrophageless PU.1 null mouse embryos by Wood, W, Turmaine, M, Weber, R, Camp, V, Maki, R A, McKercher, S R, Martin, P

“…Apoptosis is one of the key tools used by an embryo to regulate cell numbers and sculpt body shape. Although massive numbers of cells die during development,…”
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The transcription factor PU.1 does not regulate lineage commitment but has lineage-specific effects by McKercher, Scott R., Henkel, Gregory W., Maki, Richard A.

“…PU.1 is a transcription factor shown to regulate the expression of many important genes in myeloid and B cells. At birth, mice homozygous for the disruption of…”
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Kinetic and structural effects of activation of bovine kidney aldose reductase by Grimshaw, C. E, Shahbaz, M, Jahangiri, G, Putney, C. G, McKercher, S. R, Mathur, E. J

“…Aldose reductase, purified to homogeneity from bovine kidney, is converted in a temperature-dependent process from a low-Km/low-Vmax form to a…”
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Myeloid development is selectively disrupted in PU.1 null mice by ANDERSON, K. L, SMITH, K. A, CONNERS, K, MCKERCHER, S. R, MAKI, R. A, TORBETT, B. E

“…The ets family transcription factor PU.1 is expressed in monocytes/macrophages, neutrophils, mast cells, B cells, and early erythroblasts, but not in T cells…”
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Differentiation of the Mononuclear Phagocyte System During Mouse Embryogenesis: The Role of Transcription Factor PU.1 by Lichanska, Agnieszka M., Browne, Catherine M., Henkel, Gregory W., Murphy, Kathleen M., Ostrowski, Michael C., McKercher, Scott R., Maki, Richard A., Hume, David A.

“…During mouse embryogenesis, macrophage-like cells arise first in the yolk sac and are produced subsequently in the liver. The onset of liver hematopoiesis is…”
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The ETS-domain: a new DNA-binding motif that recognizes a purine-rich core DNA sequence by Karim, F D, Urness, L D, Thummel, C S, Klemsz, M J, McKercher, S R, Celada, A, Van Beveren, C, Maki, R A, Gunther, C V, Nye, J A

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Commitment to the Monocytic Lineage Occurs in the Absence of the Transcription Factor PU.1 by Henkel, Gregory W., McKercher, Scott R., Leenen, Pieter J.M., Maki, Richard A.

“…Mice homozygous for the disruption of the PU.1 (Spi-1) gene do not produce mature macrophages. In determining the role of PU.1 in macrophage differentiation,…”
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Nucleotide sequence of the mouse hck gene by KLEMSZ, M. J, MCKERCHER, S. R, MAKI, R. A

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New Insights on DNA Recognition by ets Proteins from the Crystal Structure of the PU.1 ETS Domain-DNA Complex by Pio, F, Kodandapani, R, Ni, C Z, Shepard, W, Klemsz, M, McKercher, S R, Maki, R A, Ely, K R

“…Transcription factors belonging to the ets family regulate gene expression and share a conserved ETS DNA-binding domain that binds to the core sequence…”
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Endocrine regulations of ovarian maturation in the cockroach Blaberus discoidalis by Keeley, L L, McKercher, S R

“…The first gonotrophic cycle of oocyte maturation was defined for virgin Blaberus discoidalis cockroaches. A high correlation was found between growth of the…”
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Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBP by Iwama, A., Zhang, P., Darlington, G. J., McKercher, S. R., Maki, R., Tenen, D. G.

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Murine GBP-2: a new IFN-gamma-induced member of the GBP family of GTPases isolated from macrophages by Vestal, D J, Buss, J E, McKercher, S R, Jenkins, N A, Copeland, N G, Kelner, G S, Asundi, V K, Maki, R A

“…We have cloned a new member of the interferon (IFN)-induced guanylate-binding protein (GBP) family of GTPases, murine GBP-2 (mGBP-2), from bone marrow-derived…”
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