Search Results - "MCINTOSH, Laura"

Genome‐Wide Association Meta‐Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci by McIntosh, Laura A., Marion, Miranda C., Sudman, Marc, Comeau, Mary E., Becker, Mara L., Bohnsack, John F., Fingerlin, Tasha E., Griffin, Thomas A., Haas, J. Peter, Lovell, Daniel J., Maier, Lisa A., Nigrovic, Peter A., Prahalad, Sampath, Punaro, Marilynn, Rosé, Carlos D., Wallace, Carol A., Wise, Carol A., Moncrieffe, Halima, Howard, Timothy D., Langefeld, Carl D., Thompson, Susan D.

“…Objective Juvenile idiopathic arthritis (JIA) is the most common childhood rheumatic disease and has a strong genomic component. To date, JIA genetic…”
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Pesticide Exposure and Neurodevelopmental Outcomes: Review of the Epidemiologic and Animal Studies by Burns, Carol J., McIntosh, Laura J., Mink, Pamela J., Jurek, Anne M., Li, Abby A.

“…Assessment of whether pesticide exposure is associated with neurodevelopmental outcomes in children can best be addressed with a systematic review of both the…”
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RocHealthData.org: Development and usage of a publicly available, geographic source of social determinants of health data by Holt, Kathleen D, Roman, Gretchen, McIntosh, Laura, Kleinsorge, Jamie, Holden-Wiltse, Jeanne, Bennett, Nancy M

“…Access to local, population specific, and timely data is vital in understanding factors that impact population health. The impact of place (neighborhood,…”
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Germline Missense Variants in the BTNL2 Gene Are Associated with Prostate Cancer Susceptibility by FITZGERALD, Liesel M, KUMAR, Akash, LI HSU, SHENDURE, Jay, STANFORD, Janet L, BOYLE, Evan A, YUZHENG ZHANG, MCINTOSH, Laura M, KOLB, Suzanne, STOTT-MILLER, Marni, SMITH, Tiffany, KARYADI, Danielle M, OSTRANDER, Elaine A

“…Rare, inherited mutations account for 5% to 10% of all prostate cancer cases. However, to date, few causative mutations have been identified. To identify rare…”
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Evaluation of Epidemiology and Animal Data for Risk Assessment: Chlorpyrifos Developmental Neurobehavioral Outcomes by Li, Abby A., Lowe, Kimberly A., McIntosh, Laura J., Mink, Pamela J.

“…Developmental neurobehavioral outcomes attributed to exposure to chlorpyrifos (CPF) obtained from epidemiologic and animal studies published before June 2010…”
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Building a scientific framework for studying hormonal effects on behavior and on the development of the sexually dimorphic nervous system by Li, Abby A., Baum, Michael J., McIntosh, Laura J., Day, Mark, Liu, Feng, Gray, L. Earl

“…There has been increasing concern that low-dose exposure to hormonally active chemicals disrupts sexual differentiation of the brain and peripheral nervous…”
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Dense genome-wide SNP linkage scan in 301 hereditary prostate cancer families identifies multiple regions with suggestive evidence for linkage by Stanford, Janet L., FitzGerald, Liesel M., McDonnell, Shannon K., Carlson, Erin E., McIntosh, Laura M., Deutsch, Kerry, Hood, Lee, Ostrander, Elaine A., Schaid, Daniel J.

“…The search for susceptibility loci in hereditary prostate cancer (HPC) has proven challenging due to genetic and disease heterogeneity. Multiple risk loci have…”
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Evaluation of Epidemiologic and Animal Data Associating Pesticides With Parkinson's Disease by Li, Abby A., Mink, Pamela J., McIntosh, Laura J., Teta, M. Jane, Finley, Brent

“…Exposure to pesticides may be a risk factor for developing Parkinson's disease (PD). To evaluate the evidence regarding this association in the scientific…”
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Glucocorticoids may alter antioxidant enzyme capacity in the brain: baseline studies by McIntosh, Laura J, Hong, Kay E, Sapolsky, Robert M

“…Glucocorticoids (GCs), the adrenal steroids secreted during stress, have been shown to increase the vulnerability of hippocampal neurons to metabolic insults,…”
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Germline Mutations in the BRCA2 Gene and Susceptibility to Hereditary Prostate Cancer by AGALLIU, Ilir, KWON, Erika M, ZADORY, Daniel, MCINTOSH, Laura, THOMPSON, Joseph, STANFORD, Janet L, OSTRANDER, Elaine A

“…Purpose: Several epidemiologic studies have reported that carriers of germline mutations in the BRCA2 gene have an increased risk of prostate cancer, with the…”
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Relation between length of hospital stay and costs of care for patients with community-acquired pneumonia by Fine, M J, Pratt, H M, Obrosky, D S, Lave, J R, McIntosh, L J, Singer, D E, Coley, C M, Kapoor, W N

“…Patients with pneumonia often remain hospitalized after becoming clinically stable, without demonstrated benefits on outcome. The purposes of this study were…”
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Disruptive effects of glucocorticoids on glutathione peroxidase biochemistry in hippocampal cultures by Patel, Ravi, McIntosh, Laura, McLaughlin, John, Brooke, Sheila, Nimon, Vitaliy, Sapolsky, Robert

“…Glucocorticoids (GCs), the adrenal steroids secreted during stress, compromise the ability of hippocampal neurons to survive various necrotic insults. We have…”
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Genome-wide linkage analyses of hereditary prostate cancer families with colon cancer provide further evidence for a susceptibility locus on 15q11-q14 by FITZGERALD, Liesel M, MCDONNELL, Shannon K, CARLSON, Erin E, LANGEBERG, Wendy, MCINTOSH, Laura M, DEUTSCH, Kerry, OSTRANDER, Elaine A, SCHAID, Daniel J, STANFORD, Janet L

“…The search for susceptibility loci in hereditary prostate cancer (HPC) is challenging because of locus and disease heterogeneity. One approach to reduce…”
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A signature for immune response correlates with HCV treatment outcome in Caucasian subjects by Hare, Brian J., Haseltine, Eric, Fleming, Mark, Chelsky, Daniel, McIntosh, Laura, Allard, Rene, Botfield, Martyn

“…This data article contains Supplementary material for a published research article describing a whole-blood proteomic signature that predicts treatment outcome…”
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Clinical grade production and characterization of a fusion protein comprised of the chemokine CCL2-ligand genetically fused to a mutated and truncated form of the Shiga A1 subunit by Su, Hongsheng, Jack, Michael, McIntosh, Laura M., Perdomo, Liliana, Choy, Bonny S.F., Finck, Barbara K., McDonald, John R.

“…First generation chemokine ligand-Shiga A1 (SA1) fusion proteins (leukocyte population modulators, LPMs) were previously only obtained in small quantities due…”
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Towards Non-Invasive Screening of Skin Lesions by Near-Infrared Spectroscopy by McIntosh, Laura M., Summers, Randy, Jackson, Michael, Mantsch, Henry H., Mansfield, James R., Howlett, Marilyn, Crowson, A. Neil, Toole, John W.P.

“…A noninvasive tool for skin tumor diagnosis would be a useful clinical adjunct. The purpose of this study was to determine whether near-infrared spectroscopy…”
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Increased Susceptibility of Alzheimer's Disease Temporal Cortex to Oxygen Free Radical-Mediated Processes by McIntosh, Laura J, Trush, Michael A, Troncoso, Juan C

“…Reactive oxygen-mediated processes are thought to contribute to the pathogenesis of Alzheimer's disease (AD). To investigate this hypothesis we studied autopsy…”
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Cy5.5-DTPA-galactosyl-dextran: a fluorescent probe for in vivo measurement of receptor biochemistry by Vera, David R., Hall, David J., Hoh, Carl K., Gallant, Pascal, McIntosh, Laura M., Mattrey, Robert F.

“…The high sensitivity of fluorescent reporters offers an opportunity to analytically probe the biochemistry of in vivo receptor systems with low target tissue…”
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Glucocorticoids may alter antioxidant enzyme capacity in the brain: kainic acid studies by McIntosh, Laura J, Cortopassi, Karen M, Sapolsky, Robert M

“…Glucocorticoids (GCs) predispose hippocampal neurons to damage during metabolic stressors. One component of hippocampal GC-endangerment may be changes in…”
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Dense genome-wide SNP linkage scan in 301 hereditary prostate cancer families identifies multiple regions with suggestive evidence for linkage by STANFORD, Janet L, FITZGERALD, Liesel M, MCDONNELL, Shannon K, CARLSON, Erin E, MCLNTOSH, Laura M, DEUTSCH, Kerry, HOOD, Lee, OSTRANDER, Elaine A, SCHAID, Daniel J

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