Search Results - "MCINNIS, M. G"
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Transcripts involved in calcium signaling and telencephalic neuronal fate are altered in induced pluripotent stem cells from bipolar disorder patients
Published in Translational psychiatry (25-03-2014)“…Bipolar disorder (BP) is a chronic psychiatric condition characterized by dynamic, pathological mood fluctuations from mania to depression. To date, a major…”
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Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus
Published in Molecular psychiatry (01-07-2002)“…Identification of the genetic bases for bipolar disorder remains a challenge for the understanding of this disease. Association between 76 candidate genes and…”
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3
Ankyrin-G regulates forebrain connectivity and network synchronization via interaction with GABARAP
Published in Molecular psychiatry (01-11-2020)“…GABAergic circuits are critical for the synchronization and higher order function of brain networks. Defects in this circuitry are linked to neuropsychiatric…”
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Correction: Ankyrin-G regulates forebrain connectivity and network synchronization via interaction with GABARAP
Published in Molecular psychiatry (01-11-2020)“…In the original version of this article, affiliation 3 was given as: “Division of Life Sciences, State Key Laboratory of Molecular Neuroscience, Hong Kong,…”
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Cytomegalovirus Antibody Elevation in Bipolar Disorder: Relation to Elevated Mood States
Published in Neural plasticity (01-01-2015)“…The neurobiology of mood states is complicated by exposure to everyday stressors (e.g., psychosocial, ubiquitous environmental infections like CMV), each…”
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Evidence for Genetic Linkage of Alzheimer's Disease to Chromosome 10q
Published in Science (American Association for the Advancement of Science) (22-12-2000)“…Recent studies suggest that insulin-degrading enzyme (IDE) in neurons and microglia degrades Aβ, the principal component of β-amyloid and one of the…”
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Genome-wide scan of bipolar disorder in 65 pedigrees: supportive evidence for linkage at 8q24, 18q22, 4q32, 2p12, and 13q12
Published in Molecular psychiatry (01-03-2003)“…The purpose of this study was to assess 65 pedigrees ascertained through a Bipolar I (BPI) proband for evidence of linkage, using nonparametric methods in a…”
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Anticipation : An old idea in new genes
Published in American journal of human genetics (01-11-1996)Get full text
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Expansion of a novel CAG trinucleotide repeat in the 5′ region of PPP2R2B is associated with SCA12
Published in Nature genetics (01-12-1999)“…The genetic aetiologies of at least 20% of autosomal dominant spinocerebellar ataxias (SCAs) have yet to be elucidated. We have recently identified a novel…”
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Alpha-2 macroglobulin is genetically associated with Alzheimer disease
Published in Nature genetics (01-08-1998)“…Alpha-2-macroglobulin (alpha-2M; encoded by the gene A2M) is a serum pan-protease inhibitor that has been implicated in Alzheimer disease (AD) based on its…”
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Findings in an independent sample support an association between bipolar affective disorder and the G72 G30 locus on chromosome 13q33
Published in Molecular psychiatry (01-01-2004)“…Markers near the nested genes G72 and G30 on chromosome 13q33 have been implicated in the etiology of schizophrenia and, recently, bipolar affective disorder…”
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The Familial Aggregation of Psychotic Symptoms in Bipolar Disorder Pedigrees
Published in The American journal of psychiatry (01-08-2001)“…OBJECTIVE: Symptomatic overlap between affective disorders and schizophrenia has long been noted. More recently, family and linkage studies have provided some…”
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Linkage of bipolar affective disorder on chromosome 8q24: follow-up and parametric analysis
Published in Molecular psychiatry (01-02-2004)“…Our group first reported a linkage finding for bipolar (BP) disorder on chromosome 8q24 in a study of 50 multiplex pedigrees, with an HLOD score reaching 2.39…”
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Genome-wide association study of bipolar disorder in European American and African American individuals
Published in Molecular psychiatry (01-08-2009)“…To identify bipolar disorder (BD) genetic susceptibility factors, we conducted two genome-wide association (GWA) studies: one involving a sample of individuals…”
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Psychiatric epigenetics : a new focus for the new century
Published in Molecular psychiatry (01-07-2000)Get full text
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A Novel, Heritable, Expanding CTG Repeat in an Intron of the SEF2-1 Gene on Chromosome 18q21.1
Published in Human molecular genetics (01-10-1997)“…There are currently 13 diseases known to be caused by unstable triplet repeat mutations; however, there are some instances (as with FRAXF and FRA16) when these…”
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Data-driven classification of bipolar I disorder from longitudinal course of mood
Published in Translational psychiatry (11-10-2016)“…The Diagnostic and Statistical Manual of Mental Disorder (DSM) classification of bipolar disorder defines categories to reflect common understanding of mood…”
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Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect
Published in American journal of human genetics (01-12-1995)“…A susceptibility gene on chromosome 18 and a parent-of-origin effect have been suggested for bipolar affective disorder (BPAD). We have studied 28 nuclear…”
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Obesity, but not metabolic syndrome, negatively affects outcome in bipolar disorder
Published in Acta psychiatrica Scandinavica (01-02-2016)“…Objective Examine the effects of obesity and metabolic syndrome on outcome in bipolar disorder. Method The Comparative Effectiveness of a Second Generation…”
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Attempted Suicide and Alcoholism in Bipolar Disorder: Clinical and Familial Relationships
Published in The American journal of psychiatry (01-12-2000)“…OBJECTIVE: This study examined the clinical and familial relationships between comorbid alcoholism and attempted suicide in affectively ill relatives of…”
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