Search Results - "MCGONIGAL, Thomas P"

The Volume of Three-Dimensional Cultures of Cancer Cells In Vitro Influences Transcriptional Profile Differences and Similarities with Monolayer Cultures and Xenografted Tumors by Boghaert, Erwin R., Lu, Xin, Hessler, Paul E., McGonigal, Thomas P., Oleksijew, Anatol, Mitten, Michael J., Foster-Duke, Kelly, Hickson, Jonathan A., Santo, Vitor E., Brito, Catarina, Uziel, Tamar, Vaidya, Kedar S.

“…Improving the congruity of preclinical models with cancer as it is manifested in humans is a potential way to mitigate the high attrition rate of new cancer…”
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Survivin Enhances Aurora-B Kinase Activity and Localizes Aurora-B in Human Cells by Chen, Jun, Jin, Sha, Tahir, Stephen K., Zhang, Haichao, Liu, Xuesong, Sarthy, Aparna V., McGonigal, Thomas P., Liu, Zhihong, Rosenberg, Saul H., Ng, Shi-Chung

“…Survivin, one of the most tumor-specific gene products, has been implicated in both anti-apoptosis and cytokinesis. However, the mechanism by which survivin…”
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ABT-888, an Orally Active Poly(ADP-Ribose) Polymerase Inhibitor that Potentiates DNA-Damaging Agents in Preclinical Tumor Models by DONAWHO, Cherrie K, YAN LUO, FERGUSON, Debra C, GHOREISHI-HAACK, Nayereh S, GRIMM, David R, GUAN, Ran, HAN, Edward K, HOLLEY-SHANKS, Rhonda R, HRISTOV, Boris, IDLER, Kenneth B, JARVIS, Ken, JOHNSON, Eric F, YANPING LUO, KLEINBERG, Lawrence R, KLINGHOFER, Vered, LASKO, Loren M, XUESONG LIU, MARSH, Kennan C, MCGONIGAL, Thomas P, MEULBROEK, Jonathan A, OLSON, Amanda M, PALMA, Joann P, RODRIGUEZ, Luis E, PENNING, Thomas D, YAN SHI, STAVROPOULOS, Jason A, TSURUTANI, Alan C, ZHU, Gui-Dong, ROSENBERG, Saul H, GIRANDA, Vincent L, FROST, David J, BAUCH, Joy L, BOUSKA, Jennifer J, BONTCHEVA-DIAZ, Velitchka D, COX, Bryan F, DEWEESE, Theodore L, DILLEHAY, Larry E

“…Purpose: To evaluate the preclinical pharmacokinetics and antitumor efficacy of a novel orally bioavailable poly(ADP-ribose) polymerase (PARP) inhibitor,…”
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The Volume of Three-Dimensional Cultures of Cancer Cells InVitro Influences Transcriptional Profile Differences and Similarities with Monolayer Cultures and Xenografted Tumors by Boghaert, Erwin R., Lu, Xin, Hessler, Paul E., McGonigal, Thomas P., Oleksijew, Anatol, Mitten, Michael J., Foster-Duke, Kelly, Hickson, Jonathan A., Santo, Vitor E., Brito, Catarina, Uziel, Tamar, Vaidya, Kedar S.

“…Improving the congruity of preclinical models with cancer as it is manifested in humans is a potential way to mitigate the high attrition rate of new cancer…”
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Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo by Luo, Yan, Shoemaker, Alexander R, Liu, Xuesong, Woods, Keith W, Thomas, Sheela A, de Jong, Ron, Han, Edward K, Li, Tongmei, Stoll, Vincent S, Powlas, Jessica A, Oleksijew, Anatol, Mitten, Michael J, Shi, Yan, Guan, Ran, McGonigal, Thomas P, Klinghofer, Vered, Johnson, Eric F, Leverson, Joel D, Bouska, Jennifer J, Mamo, Mulugeta, Smith, Richard A, Gramling-Evans, Emily E, Zinker, Bradley A, Mika, Amanda K, Nguyen, Phong T, Oltersdorf, Tilman, Rosenberg, Saul H, Li, Qun, Giranda, Vincent L

“…The Akt kinases are central nodes in signal transduction pathways that are important for cellular transformation and tumor progression. We report the…”
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Expression of the gene coding for the major outer capsid protein of SA-11 rotavirus in a baculovirus system by McGonigal, T P, Turon, M C, Komar-Hartnett, K, Kister, S E, Smith, R E

“…The gene coding for the major outer capsid protein (VP7) of simian rotavirus SA-11 has been expressed in a baculovirus-insect cell system. The resulting…”
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