Search Results - "MCGADY, Debra Lucas"
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A Selective Phosphatase of Regenerating Liver Phosphatase Inhibitor Suppresses Tumor Cell Anchorage-Independent Growth by a Novel Mechanism Involving p130Cas Cleavage
Published in Cancer research (Chicago, Ill.) (15-02-2008)“…The phosphatase of regenerating liver (PRL) family, a unique class of oncogenic phosphatases, consists of three members: PRL-1, PRL-2, and PRL-3. Aberrant…”
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Abstract 4827: Humanized hepsin neutralizing antibody RO5486055 inhibits tumor growth and leads to accumulation of hepsin substrate laminin-332
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Hepsin is overexpressed in prostate and other cancers where it is implicated in promoting tumor growth, invasion, and metastasis. To further our understanding…”
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High-throughput methods for measuring heparanase activity and screening potential antimetastatic and anti-inflammatory agents
Published in Analytical biochemistry (15-10-2004)“…Heparanase plays an important role in the degradation of the extracellular matrix. It is implicated in inflammation, tumor angiogenesis and metastasis. We have…”
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