Search Results - "MCEWEN, B"

Allostasis and Allostatic Load: Implications for Neuropsychopharmacology by McEwen, Bruce S.

“…The primary hormonal mediators of the stress response, glucocorticoids and catecholamines, have both protective and damaging effects on the body. In the short…”
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Stress-induced structural plasticity of medial amygdala stellate neurons and rapid prevention by a candidate antidepressant by Lau, T, Bigio, B, Zelli, D, McEwen, B S, Nasca, C

“…The adult brain is capable of adapting to internal and external stressors by undergoing structural plasticity, and failure to be resilient and preserve normal…”
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Insulin resistance—a missing link no more by Rasgon, N L, McEwen, B S

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Mechanisms for acute stress-induced enhancement of glutamatergic transmission and working memory by Yuen, E Y, Liu, W, Karatsoreos, I N, Ren, Y, Feng, J, McEwen, B S, Yan, Z

“…Corticosteroid stress hormones have a strong impact on the function of prefrontal cortex (PFC), a central region controlling cognition and emotion, though the…”
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Psychosocial stress reversibly disrupts prefrontal processing and attentional control by Liston, C, McEwen, B.S, Casey, B.J

“…Relatively little is known about the long-term neurobiological sequelae of chronic stress, which predisposes susceptible patients to neuropsychiatric…”
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Estrogen protects against the detrimental effects of repeated stress on glutamatergic transmission and cognition by Wei, J, Yuen, E Y, Liu, W, Li, X, Zhong, P, Karatsoreos, I N, McEwen, B S, Yan, Z

“…Converging evidence suggests that females and males show different responses to stress; however, little is known about the mechanism underlying the sexually…”
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Mind the gap: glucocorticoids modulate hippocampal glutamate tone underlying individual differences in stress susceptibility by Nasca, C, Bigio, B, Zelli, D, Nicoletti, F, McEwen, B S

“…Why do some individuals succumb to stress and develop debilitating psychiatric disorders, whereas others adapt well in the face of adversity? There is a gap in…”
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Sex, stress and the hippocampus: allostasis, allostatic load and the aging process by McEwen, Bruce S

“…The adaptive responses of the body that maintain homeostasis in response to stressors can be called “allostasis”, meaning “achieving stability through change”…”
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Disruption of fatty acid amide hydrolase activity prevents the effects of chronic stress on anxiety and amygdalar microstructure by Hill, M N, Kumar, S A, Filipski, S B, Iverson, M, Stuhr, K L, Keith, J M, Cravatt, B F, Hillard, C J, Chattarji, S, McEwen, B S

“…Hyperactivation of the amygdala following chronic stress is believed to be one of the primary mechanisms underlying the increased propensity for anxiety-like…”
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Dynamic plasticity: The role of glucocorticoids, brain-derived neurotrophic factor and other trophic factors by Gray, J.D, Milner, T.A, McEwen, B.S

“…Highlights ► This review summarizes the effects of glucocorticoids and BDNF on neural plasticity. ► BDNF localization and activation of its receptors are…”
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Nondrowning Asphyxia in Veterinary Forensic Pathology: Suffocation, Strangulation, and Mechanical Asphyxia by McEwen, B. J.

“…Asphyxia in a forensic context refers to death by rapid cerebral anoxia or hypoxia due to accidental or nonaccidental injury. Death due to nondrowning asphyxia…”
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Lithium's role in neural plasticity and its implications for mood disorders by Gray, J. D., McEwen, B. S.

“…Objective Lithium (Li) is often an effective treatment for mood disorders, especially bipolar disorder (BPD), and can mitigate the effects of stress on the…”
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Hippocampal gene expression changes underlying stress sensitization and recovery by Gray, J D, Rubin, T G, Hunter, R G, McEwen, B S

“…Chronic and acute stressors have been linked to changes in hippocampal function and anxiety-like behaviors. Both produce changes in gene expression, but the…”
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The neurobiological properties of tianeptine (Stablon): from monoamine hypothesis to glutamatergic modulation by McEwen, B S, Chattarji, S, Diamond, D M, Jay, T M, Reagan, L P, Svenningsson, P, Fuchs, E

“…Tianeptine is a clinically used antidepressant that has drawn much attention, because this compound challenges traditional monoaminergic hypotheses of…”
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Neurobiology of mood, anxiety, and emotions as revealed by studies of a unique antidepressant: tianeptine by MCEWEN, B. S, OLIE, J. P

“…Recent studies have provided evidence that structural remodeling of certain brain regions is a feature of depressive illness, and the postulated underlying…”
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Structural and functional alterations to rat medial prefrontal cortex following chronic restraint stress and recovery by Goldwater, D.S, Pavlides, C, Hunter, R.G, Bloss, E.B, Hof, P.R, McEwen, B.S, Morrison, J.H

“…Abstract Chronic stress has been shown in animal models to result in altered dendritic morphology of pyramidal neurons of the medial prefrontal cortex (mPFC)…”
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Veterinary Forensic Pathology: Drowning and Bodies Recovered From Water by McEwen, B. J., Gerdin, J.

“…Determining the cause of death in animals recovered from bodies of water, swimming pools, or other water-containing vessels is challenging. Animals recovered…”
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Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex by Radley, J.J, Sisti, H.M, Hao, J, Rocher, A.B, McCall, T, Hof, P.R, McEwen, B.S, Morrison, J.H

“…Both the hippocampus and the medial prefrontal cortex (mPFC) play an important role in the negative feedback regulation of hypothalamic–pituitary–adrenal (HPA)…”
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Estrogen actions in the central nervous system by McEwen, B S, Alves, S E

“…This article will review the neural actions of estrogens in the central nervous system, focusing on brain structures outside of the hypothalamus and on…”
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Sex, stress and the brain: interactive actions of hormones on the developing and adult brain by McEwen, B. S.

“…Abstract The brain is a target of steroid hormone actions that affect brain architecture, molecular and neurochemical processes, behavior and neuroprotection…”
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