Search Results - "MCDOWALL, Jennifer"
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Bacterial formate hydrogenlyase complex
Published in Proceedings of the National Academy of Sciences - PNAS (23-09-2014)“…Significance The isolation of an active formate hydrogenlyase is a breakthrough in understanding the molecular basis of bacterial hydrogen production. For over…”
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The dual-function chaperone HycH improves assembly of the formate hydrogenlyase complex
Published in Biochemical journal (01-09-2017)“…The assembly of multi-protein complexes requires the concerted synthesis and maturation of its components and subsequently their co-ordinated interaction. The…”
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Dissection and engineering of the Escherichia coli formate hydrogenlyase complex
Published in FEBS letters (07-10-2015)“…•Gene deletions identify the stable core complex of bacterial formate hydrogenlyase.•Synthetic biology approaches generated an active, stable fusion…”
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Steady-State Kinetics of α‑Synuclein Ferrireductase Activity Identifies the Catalytically Competent Species
Published in Biochemistry (Easton) (16-05-2017)“…α-Synuclein (α-syn) is a cytosolic protein known for its association with neurodegenerative diseases, including Parkinson’s disease and other…”
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Alpha-synuclein ferrireductase activity is detectible in vivo, is altered in Parkinson's disease and increases the neurotoxicity of DOPAL
Published in Molecular and cellular neuroscience (01-12-2017)“…The normal cellular role of α-synuclein is of potential importance in understanding diseases in which an aggregated form of the protein has been implicated. A…”
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Analysis of hydrogenase 1 levels reveals an intimate link between carbon and hydrogen metabolism in Escherichia coli K-12
Published in Microbiology (Society for General Microbiology) (01-03-2012)“…Two of the three [NiFe]-hydrogenases (Hyd) of Escherichia coli have a hydrogen-uptake function in anaerobic metabolism. While Hyd-2 is maximally synthesized…”
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Dissection and engineering of theEscherichia coli formate hydrogenlyase complex
Published in FEBS letters (07-10-2015)“…TheEscherichia coli formate hydrogenlyase (FHL) complex is produced under fermentative conditions and couples formate oxidation to hydrogen production. In this…”
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Diverse tetracycline resistance genotypes of Megasphaera elsdenii strains selectively cultured from swine feces
Published in Applied and Environmental Microbiology (01-06-2004)“…A total of 30 Megasphaera elsdenii strains, selectively isolated from the feces of organically raised swine by using Me109 M medium, and one bovine strain were…”
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An Integrated, Functionally Annotated Gene Map of the DXS8026–ELK1 Interval on Human Xp11.3–Xp11.23: Potential Hotspot for Neurogenetic Disorders
Published in Genomics (San Diego, Calif.) (01-04-2002)“…Human chromosome Xp11.3–Xp11.23 encompasses the map location for a growing number of diseases with a genetic basis or genetic component. These include several…”
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InterPro protein classification
Published in Methods in molecular biology (Clifton, N.J.) (2011)“…Improvements in nucleotide sequencing technology have resulted in an ever increasing number of nucleotide and protein sequences being deposited in databases…”
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Prioritizing patent sequence search results using annotation-rich data
Published in World patent information (01-09-2011)“…The European Bioinformatics Institute (EMBL-EBI) provides a free-access sequence search service that combines some of the most comprehensive, annotation-rich…”
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Bacterial formate hydrogenlyase complex
Published in Proceedings of the National Academy of Sciences - PNAS (23-09-2014)Get full text
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InterPro, progress and status in 2005
Published in Nucleic acids research (01-01-2005)“…InterPro, an integrated documentation resource of protein families, domains and functional sites, was created to integrate the major protein signature…”
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ON THE RAMPARTS: EDTPA AND THE FIGHT TO RECLAIM OUR BELOVED PROFESSION
Published in Counterpoints (New York, N.Y.) (01-01-2015)Get full text
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Bioinformatics training: a review of challenges, actions and support requirements
Published in Briefings in bioinformatics (01-11-2010)“…As bioinformatics becomes increasingly central to research in the molecular life sciences, the need to train non-bioinformaticians to make the most of…”
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iAnn: an event sharing platform for the life sciences
Published in Bioinformatics (01-08-2013)“…We present iAnn, an open source community-driven platform for dissemination of life science events, such as courses, conferences and workshops. iAnn allows…”
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Bioinformatics Training Network (BTN): a community resource for bioinformatics trainers
Published in Briefings in bioinformatics (01-05-2012)“…Funding bodies are increasingly recognizing the need to provide graduates and researchers with access to short intensive courses in a variety of disciplines,…”
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Bioinformatics training: a review of challenges, actions and support requirements: Education in Bioinformatics
Published in Briefings in bioinformatics (2010)Get full text
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InterPro, progress and status in 2005
Published in Nucleic acids research (2005)“…InterPro, an integrated documentation resource of protein families, domains and functional sites, was created to integrate the major protein signature…”
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