Search Results - "MCCOLM, A. A"

Inhibitors of Type II NADH:Menaquinone Oxidoreductase Represent a Class of Antitubercular Drugs by Weinstein, Edward A., Yano, Takahiro, Li, Lin-Sheng, Avarbock, David, Avarbock, Andrew, Helm, Douglas, McColm, Andrew A., Duncan, Ken, Lonsdale, John T., Rubin, Harvey, Chance, Britton

“…Mycobacterium tuberculosis (Mtb) is an obligate aerobe that is capable of long-term persistence under conditions of low oxygen tension. Analysis of the Mtb…”
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Iron acquisition and virulence in Helicobacter pylori: a major role for FeoB, a high‐affinity ferrous iron transporter by Velayudhan, Jyoti, Hughes, Nicky J., McColm, Andrew A., Bagshaw, Julie, Clayton, Chris L., Andrews, Simon C., Kelly, David J.

“…The genome sequence of Helicobacter pylori suggests that this bacterium possesses several Fe acquisition systems, including both Fe2+‐ and Fe3+‐citrate…”
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Helicobacter pylori Possesses Two CheY Response Regulators and a Histidine Kinase Sensor, CheA, Which Are Essential for Chemotaxis and Colonization of the Gastric Mucosa by FOYNES, S, DORRELL, N, WARD, S. J, STABLER, R. A, MCCOLM, A. A, RYCROFT, A. N, WREN, B. W

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Characterization of Helicobacter pylori PldA, a phospholipase with a role in colonization of the gastric mucosa by Dorrell, Nick, Martino, M.Celeste, Stabler, Richard A., Ward, Stephen J., Zhang, Zun W., McColm, Andy A., Farthing, Michael J.G., Wren, Brendan W.

“…Background & Aims: Phospholipase activity may play a role in the pathogenicity of Helicobacter pylori. Furthermore, some drugs that are effective against H…”
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Detection of Mycobacterium tuberculosis Group Organisms in Human and Mouse Joint Tissue by Reverse Transcriptase PCR: Prevalence in Diseased Synovial Tissue Suggests Lack of Specific Association with Rheumatoid Arthritis by KEMPSELL, Karen E, COX, Charles J, MCCOLM, Andrew A, BAGSHAW, Julie A, REECE, Richard, VEALE, Douglas J, EMERY, Paul, ISAACS, John D, GASTON, J. S, CROWE, J. Scott

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Gastric anti-secretory, mucosal protective, anti-pepsin and anti-Helicobacter properties of ranitidine bismuth citrate by Stables, R, Campbell, C J, Clayton, N M, Clitherow, J W, Grinham, C J, McColm, A A, McLaren, A, Trevethick, M A

“…Ranitidine bismuth citrate is a novel compound formed from ranitidine and a bismuth citrate complex. In conscious dogs, ranitidine bismuth citrate had similar…”
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Variation in germination of Clostridium difficile clinical isolates correlates to disease severity by Carlson, Paul E., Kaiser, Alyssa M., McColm, Sarah A., Bauer, Jessica M., Young, Vincent B., Aronoff, David M., Hanna, Philip C.

“…Over the past two decades, Clostridium difficile infections have been increasing in both number and severity throughout the world. As with other spore forming…”
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Ranitidine bismuth citrate: a novel anti-ulcer agent with different physico-chemical characteristics and improved biological activity to a bismuth citrate-ranitidine admixture by McColm, A A, McLaren, A, Klinkert, G, Francis, M R, Connolly, P C, Grinham, C J, Campbell, C J, Selway, S, Williamson, R

“…Ranitidine bismuth citrate (RBC) is a new chemical entity for the treatment of peptic ulcer disease. RBC is freely soluble in water (more than 600 mg/mL at pH…”
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H. pylori adhesion and Lewis X by Martin, Stephen L., McColm, Andrew A., Appelmelk, Ben J.

“…GASTROENTEROLOGY 2000;119:1414-1415…”
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Functional analysis of the roles of FliQ and FlhB in flagellar expression in Helicobacter pylori by Foynes, Susan, Dorrell, Nick, Ward, Stephen J., Zhang, Zun W., McColm, Andy A., Farthing, Mike J.G., Wren, Brendan W.

“…Abstract Expression of the two Helicobacter pylori flagellin proteins FlaA and FlaB is required for full motility and persistent infection of the gastric…”
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Phase variation in Helicobacter pylori lipopolysaccharide due to changes in the lengths of poly(C) tracts in alpha 3-fucosyltransferase genes by Appelmelk, B J, Martin, S L, Monteiro, MA, Clayton, ChA, McColm, A A, Zheng, P, Verboom, Th, Maaskant, J J, Van den Eijnden, DH, Hokke, CH, Perry, M B, Vandenbroucke-Grauls, CMJE, Kusters, J G

“…The lipopolysaccharide (LPS) of Helicobacter pylori expresses the Lewis x (Le super(x)) and/or Le super(y) antigen. We have shown previously that H. pylori LPS…”
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Functional analysis of the roles of FliQ and FlhB in flagellar expression in Helicobacter pylori by Foynes, Susan, Dorrell, Nick, Ward, Stephen J, Zhang, Zun W, McColm, Andy A, Farthing, Mike J.G, Wren, Brendan W

“…Expression of the two Helicobacter pylori flagellin proteins FlaA and FlaB is required for full motility and persistent infection of the gastric mucosa. The…”
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Ranitidine bismuth citrate and clarithromycin, alone or in combination, for eradication of Helicobacter mustelae infection in ferrets by Marini, R P, Fox, J G, Taylor, N S, Yan, L, McColm, A A, Williamson, R

“…To determine whether ranitidine bismuth citrate, clarithromycin, or a combination of ranitidine bismuth citrate and clarithromycin would be efficacious in…”
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Comparative pharmacokinetics of ceftazidime in fibrin clots and cardiac vegetations in rabbits with Staphylococcus aureus endocarditis by MCCOLM, A. A, RYAN, D. M

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Differential response to benzylpenicillin in vivo of tolerant and non-tolerant variants of Streptococcus sanguis II by Meeson, J, McColm, A A, Acred, P, Greenwood, D

“…A variant that was highly tolerant to benzylpenicillin was obtained from a non-tolerant clinical isolate of Streptococcus sanguis II by repeated exposure to…”
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Penetration of beta-lactam antibiotics into cardiac vegetations, aorta and heart muscle in experimental Staphylococcus aureus endocarditis: comparison of ceftazidime, cefuroxime and methicillin by McColm, A A, Ryan, D M

“…The penetration of ceftazidime, cefuroxime and methicillin into cardiac vegetations, normal aorta wall tissue, heart muscle and heart muscle tissue fluid was…”
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Development of a 14C-urea breath test in ferrets colonised with Helicobacter mustelae: effects of treatment with bismuth, antibiotics, and urease inhibitors by McColm, A A, Bagshaw, J A, O'Malley, C F

“…A 14C-urea breath test analogous to its clinical counterpart is described for use in ferrets naturally or experimentally infected with Helicobacter mustelae…”
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Penetration of ceftazidime into the rabbit respiratory tract by McColm, A A, Ryan, D M

“…A procedure is described for the direct collection of bronchial or tracheal fluid samples on to paper discs. Using the procedure, the pharmacokinetics of…”
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Evaluation of ceftazidime in experimental Klebsiella pneumoniae pneumonia: comparison with other antibiotics and measurement of its penetration into respiratory tissues and secretions by McColm, A A, Shelley, E, Ryan, D M, Acred, P

“…The activity of ceftazidime was examined in a murine model of Klebsiella pneumoniae pneumonia in which the antibiotic was administered subcutaneously 6 h after…”
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Lipidic peptides. V: Penicillin and cephalosporin acid conjugates with increased lipophilic character by Hughes, R A, Toth, I, Ward, P, McColm, A M, Cox, D M, Anderson, G J, Gibbons, W A

“…Lipophilic, double-ester derivatives of beta-lactam antibiotics with methylene, ethylene, and propylene spacers were prepared by crown-ether-assisted coupling…”
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