Search Results - "MCCLAIN, DON A"

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    MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity by Kusminski, Christine M, Holland, William L, Sun, Kai, Park, Jiyoung, Spurgin, Stephen B, Lin, Ying, Askew, G Roger, Simcox, Judith A, McClain, Don A, Li, Cai, Scherer, Philipp E

    Published in Nature medicine (01-10-2012)
    “…Obesity is often associated with mitochondrial dysfunction. What is not clear, however, is whether this is a cause or a consequence of the condition and its…”
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  2. 2

    MitoNEET, a key regulator of mitochondrial function and lipid homeostasis by Kusminski, Christine M., Holland, William L., Sun, Kai, Park, Jiyoung, Spurgin, Stephen B., Lin, Ying, Askew, G. Roger, Simcox, Judith A., McClain, Don A., Li, Cai, Scherer, Philipp E.

    Published in Nature medicine (09-09-2012)
    “…We examined rodent models with altered levels of mitoNEET, a protein residing in the mitochondrial outer membrane. Adipocyte-specific overexpression of…”
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    Dissection of the growth versus metabolic effects of insulin and insulin-like growth factor-I in transfected cells expressing kinase-defective human insulin receptors by McClain, D A, Maegawa, H, Thies, R S, Olefsky, J M

    Published in The Journal of biological chemistry (25-01-1990)
    “…We have recently reported that the expression of an in vitro mutated, kinase-defective insulin receptor (A/K1018) leads to cellular insulin resistance when…”
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    Journal Article