Search Results - "MCCLAIN, DON A"
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MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity
Published in Nature medicine (01-10-2012)“…Obesity is often associated with mitochondrial dysfunction. What is not clear, however, is whether this is a cause or a consequence of the condition and its…”
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MitoNEET, a key regulator of mitochondrial function and lipid homeostasis
Published in Nature medicine (09-09-2012)“…We examined rodent models with altered levels of mitoNEET, a protein residing in the mitochondrial outer membrane. Adipocyte-specific overexpression of…”
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Hexosamine Excess in Liver results in Obesity, Hypertriglyceridemia, and Glucose Intolerance
Published in Diabetes (New York, N.Y.) (01-05-1999)Get full text
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Regulation of Insulin by Hexosamines in Transgenic Mice Over-Expressing Glutamine: Fructose-6-Phosphate Amidotransferase in Beta Cells
Published in Diabetes (New York, N.Y.) (01-05-1999)Get full text
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Insulin Resistance Induced by High Fat Feeding and Increased Hexosamine Flux Share a Common Pathway
Published in Diabetes (New York, N.Y.) (01-05-1999)Get full text
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Dissection of the growth versus metabolic effects of insulin and insulin-like growth factor-I in transfected cells expressing kinase-defective human insulin receptors
Published in The Journal of biological chemistry (25-01-1990)“…We have recently reported that the expression of an in vitro mutated, kinase-defective insulin receptor (A/K1018) leads to cellular insulin resistance when…”
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