Search Results - "MAYR, Doris"

The ARID1A, p53 and ß-Catenin statuses are strong prognosticators in clear cell and endometrioid carcinoma of the ovary and the endometrium by Heckl, Marlene, Schmoeckel, Elisa, Hertlein, Linda, Rottmann, Miriam, Jeschke, Udo, Mayr, Doris

“…The objective of this study was to evaluate the prognostic value of ARID1A, p53, p21, p16 and ß-Catenin in endometrioid and clear cell ovarian and endometrial…”
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AP4 Encodes a c-MYC-Inducible Repressor of p21 by Jung, Peter, Menssen, Antje, Mayr, Doris, Hermeking, Heiko

“…In the majority of human tumors, expression of the c-MYC oncogene becomes constitutive. Here, we report that c-MYC directly regulates the expression of AP4 via…”
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Two-Pore Channel Function Is Crucial for the Migration of Invasive Cancer Cells by Nguyen, Ong Nam Phuong, Grimm, Christian, Schneider, Lina S, Chao, Yu-Kai, Atzberger, Carina, Bartel, Karin, Watermann, Anna, Ulrich, Melanie, Mayr, Doris, Wahl-Schott, Christian, Biel, Martin, Vollmar, Angelika M

“…Metastatic invasion is the major cause of cancer-related deaths. In this study, we introduce two-pore channels (TPC), a recently described class of NAADP- and…”
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CCL1 is a major regulatory T cell attracting factor in human breast cancer by Kuehnemuth, Benjamin, Piseddu, Ignazio, Wiedemann, Gabriela M, Lauseker, Michael, Kuhn, Christina, Hofmann, Simone, Schmoeckel, Elisa, Endres, Stefan, Mayr, Doris, Jeschke, Udo, Anz, David

“…Regulatory T cells (Treg) suppress cytotoxic T cell anti-tumoral immune responses and thereby promote tumor progression. Prevention of intratumoral Treg…”
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Carbonic anhydrase XII as biomarker and therapeutic target in ovarian carcinomas by Hiepp, Lisa, Mayr, Doris, Gärtner, Kathrin, Schmoeckel, Elisa, Klauschen, Frederick, Burges, Alexander, Mahner, Sven, Zeidler, Reinhard, Czogalla, Bastian

“…Targeting the tumor-associated carbonic anhydrase XII (CA XII) is considered a promising strategy to improve cancer treatment. As such progress is highly…”
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Galectins-1, -3, and -7 Are Prognostic Markers for Survival of Ovarian Cancer Patients by Schulz, Heiko, Schmoeckel, Elisa, Kuhn, Christina, Hofmann, Simone, Mayr, Doris, Mahner, Sven, Jeschke, Udo

“…There is a tremendous need for developing new useful prognostic factors in ovarian cancer. Galectins are a family of carbohydrate binding proteins which have…”
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Modulation of Liver Inflammation and Fibrosis by Interleukin-37 by Mountford, Steffeni, Effenberger, Maria, Noll-Puchta, Heidi, Griessmair, Lucas, Ringleb, Andrea, Haas, Sonja, Denk, Gerald, Reiter, Florian P, Mayr, Doris, Dinarello, Charles A, Tilg, Herbert, Bufler, Philip

“…Chronic inflammation induces liver fibrosis, cirrhosis and potentially liver cancer. Kupffer cells modulate hepatic stellate cells by secreting immunologically…”
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Immunogenomic Identification for Predicting the Prognosis of Cervical Cancer Patients by Wang, Qun, Vattai, Aurelia, Vilsmaier, Theresa, Kaltofen, Till, Steger, Alexander, Mayr, Doris, Mahner, Sven, Jeschke, Udo, Hildegard Heidegger, Helene

“…Cervical cancer is primarily caused by the infection of high-risk human papillomavirus (hrHPV). Moreover, tumor immune microenvironment plays a significant…”
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KRAS and BRAF mutations in ovarian tumors: A comprehensive study of invasive carcinomas, borderline tumors and extraovarian implants by Mayr, Doris, Hirschmann, Astrid, Löhrs, Udo, Diebold, Joachim

“…Mutations of BRAF, a downstream mediator of K-RAS, have been described in serous borderline tumors of the ovary. Data concerning other types of ovarian tumors…”
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Overall Survival of Ovarian Cancer Patients Is Determined by Expression of Galectins-8 and -9 by Schulz, Heiko, Kuhn, Christina, Hofmann, Simone, Mayr, Doris, Mahner, Sven, Jeschke, Udo, Schmoeckel, Elisa

“…The evaluation of new prognostic factors that can be targeted in ovarian cancer diagnosis and therapy is of the utmost importance. Galectins are a family of…”
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Interaction of ERα and NRF2 Impacts Survival in Ovarian Cancer Patients by Czogalla, Bastian, Kahaly, Maja, Mayr, Doris, Schmoeckel, Elisa, Niesler, Beate, Kolben, Thomas, Burges, Alexander, Mahner, Sven, Jeschke, Udo, Trillsch, Fabian

“…Nuclear factor erythroid 2-related factor 2 (NRF2) regulates cytoprotective antioxidant processes. In this study, the prognostic potential of NRF2 and its…”
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The Association between Vitamin D Receptor Expression and Prolonged Overall Survival in Breast Cancer by Ditsch, Nina, Toth, Bettina, Mayr, Doris, Lenhard, Miriam, Gallwas, Julia, Weissenbacher, Tobias, Dannecker, Christian, Friese, Klaus, Jeschke, Udo

“…In this study, we analyzed vitamin D receptor (VDR) expression and survival in a breast cancer patient cohort of 82 breast cancer patients. Immunohistochemical…”
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Analysis of FoxP3+ T-regulatory cells and CD8+ T-cells in ovarian carcinoma: location and tumor infiltration patterns are key prognostic markers by Hermans, Cecilia, Anz, David, Engel, Jutta, Kirchner, Thomas, Endres, Stefan, Mayr, Doris

“…Tumor infiltrating CD4+CD25+FoxP3+ regulatory immune cells (Treg) have been associated with impaired anti-tumor immune response and unfavorable prognosis for…”
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MSX1-A Potential Marker for Uterus-Preserving Therapy of Endometrial Carcinomas by Eppich, Simon, Kuhn, Christina, Schmoeckel, Elisa, Mayr, Doris, Mahner, Sven, Jeschke, Udo, Gallwas, Julia, Heidegger, Helene Hildegard

“…Prognostic factors are of great interest in patients with endometrial cancer. One potential factor could be the protein MSX1, a transcription repressor, that…”
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Regulatory T Cell Apoptosis during Preeclampsia May Be Prevented by Gal-2 by Meister, Sarah, Hahn, Laura, Beyer, Susanne, Mannewitz, Mareike, Perleberg, Carolin, Schnell, Konstantin, Anz, David, Corradini, Stefanie, Schmoeckel, Elisa, Mayr, Doris, Hasbargen, Uwe, Zati Zehni, Alaleh, Mahner, Sven, Jeschke, Udo, Kolben, Thomas

“…There are several open questions to be answered regarding the pathophysiology of the development of preeclampsia (PE). Numerous factors are involved in its…”
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L-Dopa-Decarboxylase (DDC) Is a Positive Prognosticator for Breast Cancer Patients and Epinephrine Regulates Breast Cancer Cell (MCF7 and T47D) Growth In Vitro According to Their Different Expression of Gi- Protein- Coupled Receptors by Tremmel, Eileen, Kuhn, Christina, Kaltofen, Till, Vilsmaier, Theresa, Mayr, Doris, Mahner, Sven, Ditsch, Nina, Jeschke, Udo, Vattai, Aurelia

“…A coherence between thyroid dysfunction and breast cancer incidence exists. Thyroid hormone metabolites bind to TAAR1 (trace amine-associated receptor 1) and…”
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Expression of Progesterone Receptor A as an Independent Negative Prognosticator for Cervical Cancer by Garrido, Fabian, Wild, Carl Mathis, Jeschke, Udo, Dannecker, Christian, Mayr, Doris, Cavailles, Vincent, Mahner, Sven, Kost, Bernd, Heidegger, Helene H, Vattai, Aurelia

“…The role of progesterone receptor A (PRA) for the survival outcome of cervical cancer patients is ambiguous. In mouse models, it has been shown that PRA plays…”
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Exclusive enteral nutrition in active pediatric Crohn disease: Effects on intestinal microbiota and immune regulation by Schwerd, Tobias, MD, Frivolt, Klara, MD, Clavel, Thomas, PhD, Lagkouvardos, Ilias, PhD, Katona, Gabor, MD, Mayr, Doris, MD, Uhlig, Holm H., MD, PhD, Haller, Dirk, PhD, Koletzko, Sibylle, MD, Bufler, Philip, MD

“…Importantly, and in addition to reduction of proinflammatory responses, EEN enhanced the capacity of antiinflammatory IL-10 to suppress LPS-induced IL-6 in…”
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PLA2G7/PAF-AH as Potential Negative Regulator of the Wnt Signaling Pathway Mediates Protective Effects in BRCA1 Mutant Breast Cancer by Liao, Yue, Badmann, Susann, Kraus, Fabian, Topalov, Nicole Elisabeth, Mayr, Doris, Kolben, Thomas, Hester, Anna, Beyer, Susanne, Mahner, Sven, Jeschke, Udo, Trillsch, Fabian, Czogalla, Bastian, Burges, Alexander

“…Past studies have confirmed that aberrant activation of the Wnt/β-catenin signaling is associated with tumorigenesis and metastasis in breast cancer, while the…”
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Assessment of intraductal carcinoma in situ (DCIS) using grating-based X-ray phase-contrast CT at conventional X-ray sources: An experimental ex-vivo study by Hellerhoff, Karin, Birnbacher, Lorenz, Sztrókay-Gaul, Anikó, Grandl, Susanne, Auweter, Sigrid, Willner, Marian, Marschner, Mathias, Mayr, Doris, Reiser, Maximilian F, Pfeiffer, Franz, Herzen, Julia

“…The extent of intraductal carcinoma in situ (DCIS) is commonly underestimated due to the discontinuous growth and lack of microcalcifications. Specimen…”
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