Search Results - "MAYERS, D. L"

A randomized study of antiretroviral management based on plasma genotypic antiretroviral resistance testing in patients failing therapy by BAXTER, J. D, MAYERS, D. L, IOANNIDIS, J. P. A, MERIGAN, T. C, WENTWORTH, D. N, NEATON, J. D, HOOVER, M. L, WINTERS, M. A, MANNHEIMER, S. B, THOMPSON, M. A, ABRAMS, D. I, BRIZZ, B. J

“…Objective: To determine the short-term effects of using genotypic antiretroviral resistance testing (GART) with expert advice in the management of patients…”
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Standardized peripheral blood mononuclear cell culture assay for determination of drug susceptibilities of clinical human immunodeficiency virus type 1 isolates by JAPOUR, A. J, MAYERS, D. L, CRUMPACKER, C. S, JOHNSON, V. A, KURITZKES, D. R, BECKETT, L. A, ARDUINO, J.-M, LANE, J, BLACK, R. J, REICHELDERFER, P. S, D'AQUILA, R. T

“…A standardized antiviral drug susceptibility assay for clinical human immunodeficiency virus type 1 (HIV-1) isolates has been developed for use in clinical…”
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Antiviral Effect and Ex Vivo CD4$^+$ T Cell Proliferation in HIV-Positive Patients as a Result of CD28 Costimulation by Levine, Bruce L., Mosca, Joseph D., Riley, James L., Carroll, Richard G., Vahey, Maryanne T., Jagodzinski, Linda L., Wagner, Kenneth F., Mayers, Douglas L., Burke, Donald S., Weislow, Owen S., St. Louis, Daniel C., June, Carl H.

“…Because stimulation of CD4$^+$ lymphocytes leads to activation of human immunodeficiency virus-type 1 (HIV-1) replication, viral spread, and cell death,…”
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Novel mutations in reverse transcriptase of human immunodeficiency virus type 1 reduce susceptibility to foscarnet in laboratory and clinical isolates by Mellors, J W, Bazmi, H Z, Schinazi, R F, Roy, B M, Hsiou, Y, Arnold, E, Weir, J, Mayers, D L

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Standardized microtiter assay for determination of syncytium-inducing phenotypes of clinical human immunodeficiency virus type 1 isolates by JAPOUR, A. J, FISCUS, S. A, ARDUINO, J.-M, MAYERS, D. L, REICHELDERFER, P. S, KURITZKES, D. R

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Brief report : primary infection with zidovudine-resistant human immunodeficiency virus type 1 by ERICE, A, MAYERS, D. L, STRIKE, D. G, SANNERUD, K. J, MCCUTCHAN, F. E, HENRY, K, BALFOUR, H. H

“…Because one of his sexual partners was receiving zidovudine (and therefore could have been harboring a high percentage of resistant HIV-1 variants), we suggest…”
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Drug-Resistant HIV-1: The Virus Strikes Back by Mayers, Douglas L

“…Mayers believes that the public health impact of drug-resistant HIV-1 will likely increase for the foreseeable future and the rapid implementation of active…”
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Genetic diversity and response to IFN of the NS3 protease gene from clinical strains of the hepatitis C virus by HOLLAND-STALEY, C. A, KOVARI, L. C, GOLENBERG, E. M, POBURSKY, K. J, MAYERS, D. L

“…The N-terminal one-third of the hepatitis C virus nonstructural gene 3 (NS3) codes for a serine protease. To investigate natural genetic diversity of this…”
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Primary Lamivudine Resistance in Acute/Early Human Immunodeficiency Virus Infection by Conway, Brian, Montessori, Valentina, Rouleau, Danielle, Montaner, Julio S. G., O'Shaughnessy, Michael V., Fransen, Signe, Shillington, Andrew, Weislow, Owen, Mayers, Douglas L.

“…Primary resistance of HIV to zidovudine was first described in 1992 and has since been identified in up to 10% of antiretroviral-naive patients in some…”
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Exotic virus infections of military significance. Hemorrhagic fever viruses and pox virus infections by Mayers, D L

“…Military personnel are frequently deployed to distant locations around the world under conditions of great stress, which involve potential exposure to…”
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Evolution of human immunodeficiency virus type 1 env sequence variation in patients with diverse rates of disease progression and T-cell function by McDonald, R A, Mayers, D L, Chung, R C, Wagner, K F, Ratto-Kim, S, Birx, D L, Michael, N L

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Anti-Human Immunodeficiency Virus 1 (HIV-1) Activities of 3-Deazaadenosine Analogs: Increased Potency Against 3'-Azido-3'-Deoxythymidine-Resistant HIV-1 Strains by Mayers, Douglas L., Mikovits, Judy A., Joshi, Bharat, Hewlett, Indira K., Estrada, Joseph S., Wolfe, Alan D., Garcia, Gregory E., Doctor, B. P., Burke, Donald S., Gordon, Richard K., Lane, James R., Chiang, Peter K.

“…3-Deazaadenosine (DZA), 3-deaza-(±)-aristeromycin (DZAri), and 3-deazaneplanocin A (DZNep) are powerful modulators of cellular processes. When tested against…”
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Standardized peripheral blood mononuclear cell culture assay for zidovudine susceptibility testing of clinical human immunodeficiency virus type 1 isolates: effect of reducing the numbers of replicates and concentrations by MARSCHNER, I. C, MAYERS, D. L, ERICE, A, SMEATON, L, JOHNSON, V. A, RICHMAN, D. D, REICHELDERFER, P, JAPOUR, A. J

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Quantitative Relationship of Circulating p24 Antigen with Human Immunodeficiency Virus (HIV) RNA and Specific Antibody in HIV-Infected Subjects Receiving Antiretroviral Therapy by Brown, Arthur E., Vahey, Maryanne T., Zhou, Susan Y. J., Chung, Raymond C.-Y., Ruiz, Nancy M., Hotbeinz, David, Lane, James R., Mayers, Douglas L.

“…To better understand the biologic meaning and potential clinical utility of p24 antigen measurements in human immunodeficiency virus (HIV) infection, p24…”
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Stavudine-Induced Macrocytosis During Therapy for Human Immunodeficiency Virus Infection by Martin, Gregory J., Blazes, David L., Mayers, Douglas L., Spooner, Katherine M.

“…Abstract only…”
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Dideoxynucleoside resistance emerges with prolonged zidovudine monotherapy by Mayers, D L, Japour, A J, Arduino, J-M, Hammer, S M, Reichman, R, Wagner, K F, Chung, R, Lane, J, Crumpacker, C S

“…Human immunodeficiency virus type 1 (HIV-1) isolates resistant to zidovudine (ZDV) have previously been demonstrated to exhibit in vitro cross-resistance to…”
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Exposure of human CD34+ cells to human immunodeficiency virus type 1 does not influence their expansion and proliferation of hematopoietic progenitors in vitro by Kaushal, S, La Russa, V F, Gartner, S, Kessler, S, Perfetto, S, Yu, Z, Ritchey, D W, Xu, J, Perera, P, Kim, J, Reid, T, Mayers, D L, St Louis, D, Mosca, J D

“…The susceptibility of highly purified human CD34+ cells to monocytotropic (Ba-L) and lymphotropic (A018-post) strains of human immunodeficiency virus-1 (HIV-1)…”
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A 14-Day Dose-Response Study of the Efficacy, Safety, and Pharmacokinetics of the Nonpeptidic Protease Inhibitor Tipranavir in Treatment-Naive HIV-1–Infected Patients by McCallister, Scott, Valdez, Hernan, Curry, Kevin, MacGregor, Thomas, Borin, Marie, Freimuth, William, Wang, Yenyung, Mayers, Douglas L

“…Tipranavir (TPV), a novel nonpeptidic protease inhibitor (NPPI), was administered to treatment-naive HIV-1–infected patients over 14 days in a randomized,…”
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Characterization of HIV isolates arising after prolonged zidovudine therapy by Mayers, D L, McCutchan, F E, Sanders-Buell, E E, Merritt, L I, Dilworth, S, Fowler, A K, Marks, C A, Ruiz, N M, Richman, D D, Roberts, C R

“…Human immunodeficiency virus type 1 (HIV-1) was isolated from five patients with late-stage disease treated with zidovudine (ZDV) for more than 1 year…”
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Hospital-Acquired Wound Mucormycosis by Paparello, Scott F., Parry, Robert L., MacGillivray, Dougald C., Brock, Nadine, Mayers, Douglas L.

“…Cutaneous infections due to fungi of the order Mucorales are uncommon and usually present as a fulminant necrotizing cellulitis. We describe a case of a…”
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