Search Results - "MAYER, E. A"

Role of diet and its effects on the gut microbiome in the pathophysiology of mental disorders by Horn, J., Mayer, D. E., Chen, S., Mayer, E. A.

“…There is emerging evidence that diet has a major modulatory influence on brain-gut-microbiome (BGM) interactions with important implications for brain health,…”
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Effect of hypnotherapy and educational intervention on brain response to visceral stimulus in the irritable bowel syndrome by Lowén, M. B. O., Mayer, E. A., Sjöberg, M., Tillisch, K., Naliboff, B., Labus, J., Lundberg, P., Ström, M., Engström, M., Walter, S. A.

“…Summary Background Gut‐directed hypnotherapy can reduce IBS symptoms, but the mechanisms underlying this therapeutic effect remain unknown. Aim To determine…”
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The neurobiology of stress and gastrointestinal disease by MAYER, E A

“…[...]recent evidence suggests a role for endogenous pain modulation systems in stress induced increase in oesophageal chemosensitivity. 168 In conclusion,…”
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The Visceral Sensitivity Index: development and validation of a gastrointestinal symptom‐specific anxiety scale by Labus, J. S., Bolus, R., Chang, L., Wiklund, I., Naesdal, J., Mayer, E. A., Naliboff, B. D.

“…Summary Background : Anxiety related to gastrointestinal sensations, symptoms or the contexts in which these may occur is thought to play a significant role in…”
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Dislocation based high-rate plasticity model and its application to plate-impact and ultra short electron irradiation simulations by Krasnikov, V.S., Mayer, A.E., Yalovets, A.P.

“…This paper focuses on the development of a plasticity model to describe high rate deformations of metals. Modeling of target mechanical response is performed…”
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Mechanisms of hypersensitivity in IBS and functional disorders by Azpiroz, F., Bouin, M., Camilleri, M., Mayer, E. A., Poitras, P., Serra, J., Spiller, R. C.

“…General introduction  The concept of visceral hypersensitivity is accepted as being germane to several functional gastrointestinal disorders (FGIDs). The…”
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Review article: modulation of the brain–gut axis as a therapeutic approach in gastrointestinal disease by MAYER, E. A., TILLISCH, K., BRADESI, S.

“…Summary Background The importance of bi‐directional brain‐gut interactions in gastrointestinal illness is increasingly being recognized, most prominently in…”
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Functional GI disorders: from animal models to drug development by Mayer, E A, Bradesi, S, Chang, L, Spiegel, B M R, Bueller, J A, Naliboff, B D

“…Despite considerable efforts by academic researchers and by the pharmaceutical industry, the development of novel pharmacological treatments for irritable…”
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Guanylate cyclase C‐mediated antinociceptive effects of linaclotide in rodent models of visceral pain by Eutamene, H., Bradesi, S., Larauche, M., Theodorou, V., Beaufrand, C., Ohning, G., Fioramonti, J., Cohen, M., Bryant, A. P., Kurtz, C., Currie, M. G., Mayer, E. A., Bueno, L.

“…Background  Linaclotide is a novel, orally administered investigational drug currently in clinical development for the treatment of constipation‐predominant…”
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Dysregulation of the hypothalamic‐pituitary‐adrenal (HPA) axis in irritable bowel syndrome by Chang, L., Sundaresh, S., Elliott, J., Anton, P. A., Baldi, P., Licudine, A., Mayer, M., Vuong, T., Hirano, M., Naliboff, B. D., Ameen, V. Z., Mayer, E. A.

“…Enhanced stress responsiveness has been implicated as a potential mechanism contributing to the pathophysiology of irritable bowel syndrome (IBS), and should…”
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Randomised clinical trial: symptoms of the irritable bowel syndrome are improved by a psycho‐education group intervention by Labus, J., Gupta, A., Gill, H. K., Posserud, I., Mayer, M., Raeen, H., Bolus, R., Simren, M., Naliboff, B. D., Mayer, E. A.

“…Summary Background Evidence supports the effectiveness of cognitive behavioural approaches in improving the symptoms of the irritable bowel syndrome (IBS)…”
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Brain imaging approaches to the study of functional GI disorders: A Rome Working Team Report by Mayer, E. A., Aziz, Q., Coen, S., Kern, M., Labus, J. S., Lane, R., Kuo, B., Naliboff, B., Tracey, I.

“…Progresses in the understanding of human brain‐gut interactions in health and disease have been limited by the lack of non‐invasive techniques to study brain…”
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Acute tryptophan depletion alters the effective connectivity of emotional arousal circuitry during visceral stimuli in healthy women by Labus, J S, Mayer, E A, Jarcho, J, Kilpatrick, L A, Kilkens, T O C, Evers, E A T, Backes, W H, Brummer, R-J M, van Nieuwenhoven, M A

“…Alterations in serotonin signalling within the brain-gut axis have been implicated in the pathophysiology of irritable bowel syndrome (IBS) and is a treatment…”
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Sex specific alterations in autonomic function among patients with irritable bowel syndrome by Tillisch, K, Mayer, E A, Labus, J S, Stains, J, Chang, L, Naliboff, B D

“…Background: Irritable bowel syndrome (IBS) is associated with increased psychological symptoms, early life stressors, and alterations in visceral perception…”
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Neonatal maternal separation alters stress-induced responses to viscerosomatic nociceptive stimuli in rat by Coutinho, S V, Plotsky, P M, Sablad, M, Miller, J C, Zhou, H, Bayati, A I, McRoberts, J A, Mayer, E A

“…This study investigated the combined effect of neonatal maternal separation and acute psychological stress on pain responses in adult rats. Long-Evans dams and…”
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An Irritable Bowel Syndrome-Specific Symptom Questionnaire: Development and Validation by WIKLUND, I. K, FULLERTON, S, HAWKEY, C. J, JONES, R. H, LONGSTRETH, G. F, MAYER, E. A, PEACOCK, R. A, WILSON, I. K, NAESDAL, J

“…Background: No self-assessment instruments are available to assess symptoms of irritable bowel syndrome (IBS). Our aim was to develop a disease-specific…”
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Symptoms and visceral perception in severe functional and organic dyspepsia by Mertz, H, Fullerton, S, Naliboff, B, Mayer, E A

“…Background—Hypersensitivity of gastric afferent pathways may play an aetiological role in symptoms of functional dyspepsia. Aims—To determine whether patients…”
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History of early life adversity is associated with increased food addiction and sex‐specific alterations in reward network connectivity in obesity by Osadchiy, V., Mayer, E. A., Bhatt, R., Labus, J. S., Gao, L., Kilpatrick, L. A., Liu, C., Tillisch, K., Naliboff, B., Chang, L., Gupta, A.

“…Summary Background Neuroimaging studies have identified obesity‐related differences in the brain's resting state activity. An imbalance between homeostatic and…”
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Improvement in pain and bowel function in female irritable bowel patients with alosetron, a 5‐HT3 receptor antagonist by CAMILLERI, M, MAYER, E. A, DROSSMAN, D. A, HEATH, A, DUKES, G. E, MCSORLEY, D, KONG, S, MANGEL, A. W, NORTHCUTT, A. R

“…Background : No currently available treatment provides consistent relief of irritable bowel syndrome. Colonic sensory and motor function are modulated partly…”
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Differences in brain responses between lean and obese women to a sweetened drink by Connolly, L., Coveleskie, K., Kilpatrick, L. A., Labus, J. S., Ebrat, B., Stains, J., Jiang, Z., Tillisch, K., Raybould, H. E., Mayer, E. A.

“…Background Ingestion of sweet food is driven by central reward circuits and restrained by endocrine and neurocrine satiety signals. The specific influence of…”
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