Search Results - "MAXWELL, R. J"

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  1. 1

    Cerebral glucose metabolism and cognition in newly diagnosed Parkinson's disease: ICICLE-PD study by Firbank, M J, Yarnall, A J, Lawson, R A, Duncan, G W, Khoo, T K, Petrides, G S, O'Brien, J T, Barker, R A, Maxwell, R J, Brooks, D J, Burn, D J

    “…ObjectiveTo assess reductions of cerebral glucose metabolism in Parkinson's disease (PD) with 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET),…”
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    Journal Article
  2. 2

    The synergistic interaction of MEK and PI3K inhibitors is modulated by mTOR inhibition by Haagensen, E J, Kyle, S, Beale, G S, Maxwell, R J, Newell, D R

    Published in British journal of cancer (10-04-2012)
    “…Background: Combined targeting of MAPK and PI3K signalling pathways may be necessary for optimal therapeutic activity in cancer. This study evaluated the MEK…”
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    Journal Article
  3. 3

    Medical graduate views on statistical learning needs for clinical practice: a comprehensive survey by MacDougall, Margaret, Cameron, Helen S, Maxwell, Simon R J

    Published in BMC medical education (31-12-2019)
    “…This paper seeks to contribute to a reputable evidence base for required competencies across different topics in statistics and probability (statistical…”
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    Journal Article
  4. 4

    Pulse transit time measured from the ECG: an unreliable marker of beat-to-beat blood pressure by Payne, R. A, Symeonides, C. N, Webb, D. J, Maxwell, S. R. J

    Published in Journal of applied physiology (1985) (01-01-2006)
    “…Clinical Pharmacology Unit, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom Submitted 3 June 2005 ; accepted in final form 30…”
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    Journal Article
  5. 5
  6. 6

    Uric acid reduces exercise-induced oxidative stress in healthy adults by Waring, W S, Convery, A, Mishra, V, Shenkin, A, Webb, D J, Maxwell, S R J

    Published in Clinical science (1979) (01-10-2003)
    “…Uric acid (UA) possesses free-radical-scavenging properties, and systemic administration is known to increase serum antioxidant capacity. However, it is not…”
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    Journal Article
  7. 7

    Effects of short-term isocapnic hyperoxia and hypoxia on cardiovascular function by Thomson, Alastair J, Drummond, Gordon B, Waring, W. Stephen, Webb, David J, Maxwell, Simon R. J

    Published in Journal of applied physiology (1985) (01-09-2006)
    “…1 Department of Anaesthesia, Critical Care and Pain Medicine, Royal Infirmary, and 2 Clinical Pharmacology Unit, Centre for Cardiovascular Science, Queen’s…”
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    Journal Article
  8. 8

    Genetic influences modulating the radiological severity of rheumatoid arthritis by Marinou, I, Maxwell, J R, Wilson, A G

    Published in Annals of the rheumatic diseases (01-03-2010)
    “…This review focuses on the contribution of genetic markers to the severity of radiological damage in rheumatoid arthritis (RA). Currently available biomarkers…”
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  9. 9

    Carbogen breathing increases prostate cancer oxygenation: a translational MRI study in murine xenografts and humans by Alonzi, R, Padhani, A R, Maxwell, R J, Taylor, N J, Stirling, J J, Wilson, J I, d′Arcy, J A, Collins, D J, Saunders, M I, Hoskin, P J

    Published in British journal of cancer (24-02-2009)
    “…Hypoxia has been associated with poor local tumour control and relapse in many cancer sites, including carcinoma of the prostate. This translational study…”
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    Journal Article
  10. 10

    The availability of prescription‐only analgesics purchased from the internet in the UK by Raine, Connie, Webb, David J., Maxwell, Simon R. J.

    Published in British journal of clinical pharmacology (01-02-2009)
    “…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Increasing numbers of people are accessing medicines from the internet. • This online market is poorly regulated and…”
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    Journal Article
  11. 11

    Lowering serum urate does not improve endothelial function in patients with type 2 diabetes by WARING, W. S, MCKNIGHT, J. A, WEBB, D. J, MAXWELL, S. R. J

    Published in Diabetologia (01-12-2007)
    “…Endothelial dysfunction contributes to excess cardiovascular risk in patients with type 2 diabetes. There is strong evidence of an association between high…”
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    Journal Article
  12. 12

    Endogenous urate production augments plasma antioxidant capacity in healthy lowland subjects exposed to high altitude by Baillie, J Kenneth, Bates, Matthew G D, Thompson, A A Roger, Waring, W Stephen, Partridge, Roland W, Schnopp, Martin F, Simpson, Alistair, Gulliver-Sloan, Fiona, Maxwell, Simon R J, Webb, David J

    Published in Chest (01-05-2007)
    “…Both tissue hypoxia in vitro, and whole-body hypoxia in vivo, have been found to promote the release of reactive oxygen species (ROS) that are potentially…”
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    Journal Article
  13. 13

    Undergraduate preparation for prescribing: the views of 2413 UK medical students and recent graduates by Heaton, Amy, Webb, David J., Maxwell, Simon R. J.

    Published in British journal of clinical pharmacology (01-07-2008)
    “…WHAT IS ALREADY KNOWN ON THIS SUBJECT • Adverse drug events are common in National Health Service (NHS) hospitals where junior doctors take responsibility for…”
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    Journal Article
  14. 14

    Rational prescribing: the principles of drug selection by Maxwell, Simon RJ

    Published in Clinical medicine (London, England) (01-10-2016)
    “…Prescribing is the most important tool used by physicians to cure illness, relieve symptoms and prevent future disease. It is also a complex intellectual task…”
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    Journal Article
  15. 15

    Morphine is an arteriolar vasodilator in man by Afshari, Reza, Maxwell, Simon R. J., Webb, David J., Bateman, D. Nicholas

    Published in British journal of clinical pharmacology (01-04-2009)
    “…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • It has been recognized for about 10 years that morphine is a veno‐dilator in man and that this effect may be related…”
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    Journal Article
  16. 16

    Systemic Uric Acid Administration Increases Serum Antioxidant Capacity in Healthy Volunteers by WARING, W. Stephen, WEBB, David J, MAXWELL, Simon R. J

    Published in Journal of cardiovascular pharmacology (01-09-2001)
    “…Oxidative stress plays an important role in the development of atherosclerosis and contributes to tissue damage that occurs as a consequence, particularly in…”
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    Journal Article
  17. 17

    Educating European (Junior) Doctors for Safe Prescribing by Maxwell, Simon R. J., Cascorbi, Ingolf, Orme, Michael, Webb, David J.

    Published in Basic & clinical pharmacology & toxicology (01-12-2007)
    “…:  Evidence of poor prescribing is widespread including overuse of medicines, underuse of effective medicines, avoidable adverse drug reactions and medication…”
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    Journal Article Conference Proceeding
  18. 18

    Uric Acid Restores Endothelial Function in Patients With Type 1 Diabetes and Regular Smokers by WARING, W. Stephen, MCKNIGHT, John A, WEBB, David J, MAXWELL, Simon R. J

    Published in Diabetes (New York, N.Y.) (01-11-2006)
    “…Uric Acid Restores Endothelial Function in Patients With Type 1 Diabetes and Regular Smokers W. Stephen Waring 1 , John A. McKnight 2 , David J. Webb 1 and…”
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  19. 19

    A generalized arterial transfer function derived at rest underestimates augmentation of central pressure after exercise by Payne, Rupert A, Teh, Chun Huat, Webb, David J, Maxwell, Simon RJ

    Published in Journal of hypertension (01-11-2007)
    “…OBJECTIVESPeripheral exercise blood pressure and resting central blood pressure are considered more relevant to cardiovascular health than resting peripheral…”
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    Journal Article
  20. 20

    Significance of systemic endotoxaemia in inflammatory bowel disease by Gardiner, K R, Halliday, M I, Barclay, G R, Milne, L, Brown, D, Stephens, S, Maxwell, R J, Rowlands, B J

    Published in Gut (01-06-1995)
    “…Quantitative and qualitative disturbances in faecal flora suggest a role for enteric bacteria and their products in the pathogenesis of inflammatory bowel…”
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    Journal Article