Search Results - "MAUTNER, Victor F"

Pronounced maternal parent-of-origin bias for type-1 NF1 microdeletions by Neuhäusler, Lisa, Summerer, Anna, Cooper, David N., Mautner, Victor-F., Kehrer-Sawatzki, Hildegard

“…Neurofibromatosis type 1 (NF1) is caused, in 4.7–11% of cases, by large deletions encompassing the NF1 gene and its flanking regions within 17q11.2. Different…”
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Management of neurofibromatosis type 1-associated plexiform neurofibromas by Fisher, Michael J, Blakeley, Jaishri O, Weiss, Brian D, Dombi, Eva, Ahlawat, Shivani, Akshintala, Srivandana, Belzberg, Allan J, Bornhorst, Miriam, Bredella, Miriam A, Cai, Wenli, Ferner, Rosalie E, Gross, Andrea M, Harris, Gordon J, Listernick, Robert, Ly, Ina, Martin, Staci, Mautner, Victor F, Salamon, Johannes M, Salerno, Kilian E, Spinner, Robert J, Staedtke, Verena, Ullrich, Nicole J, Upadhyaya, Meena, Wolters, Pamela L, Yohay, Kaleb, Widemann, Brigitte C

“…Plexiform Neurofibromas (PN) are a common manifestation of the genetic disorder neurofibromatosis type 1 (NF1). These benign nerve sheath tumors often cause…”
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The effect of pregnancy on growth-dynamics of neurofibromas in Neurofibromatosis type 1 by Well, Lennart, Jaeger, Anna, Kehrer-Sawatzki, Hildegard, Farschtschi, Said, Avanesov, Maxim, Sauer, Markus, de Sousa, Manuela Tavares, Bannas, Peter, Derlin, Thorsten, Adam, Gerhard, Mautner, Victor F, Salamon, Johannes M

“…Patients with Neurofibromatosis type 1 (NF1) develop plexiform neurofibromas (PNF) and cutaneous neurofibromas. These tumors are a major cause of the patient's…”
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Quantitative assessment of whole-body tumor burden in adult patients with neurofibromatosis by Plotkin, Scott R, Bredella, Miriam A, Cai, Wenli, Kassarjian, Ara, Harris, Gordon J, Esparza, Sonia, Merker, Vanessa L, Munn, Lance L, Muzikansky, Alona, Askenazi, Manor, Nguyen, Rosa, Wenzel, Ralph, Mautner, Victor F

“…Patients with neurofibromatosis 1 (NF1), NF2, and schwannomatosis are at risk for multiple nerve sheath tumors and premature mortality. Traditional magnetic…”
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Assessment of benign tumor burden by whole-body MRI in patients with neurofibromatosis 1 by Mautner, Victor-F, Asuagbor, Florence A, Dombi, Eva, Fünsterer, Carsten, Kluwe, Lan, Wenzel, Ralf, Widemann, Brigitte C, Friedman, Jan M

“…People with neurofibromatosis 1 (NF1) have multiple benign neurofibromas and a 10% lifetime risk of developing malignant peripheral nerve sheath tumors…”
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Screening 500 unselected neurofibromatosis 1 patients for deletions of the NF1 gene by Kluwe, Lan, Siebert, Reiner, Gesk, Stefan, Friedrich, Reinhard E., Tinschert, Sigrid, Kehrer-Sawatzki, Hildegard, Mautner, Victor-F.

“…A total of 500 unselected unrelated neurofibromatosis 1 (NF1) patients were screened for deletions of the NF1 gene. After excluding 67 patients with known…”
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Nerve Sheath Tumors in Neurofibromatosis Type 1: Assessment of Whole-Body Metabolic Tumor Burden Using F-18-FDG PET/CT by Salamon, Johannes, Papp, László, Tóth, Zoltán, Laqmani, Azien, Apostolova, Ivayla, Adam, Gerhard, Mautner, Victor F, Derlin, Thorsten

“…To determine the metabolically active whole-body tumor volume (WB-MTV) on F-18-fluorodeoxyglucose positron emission tomography/computed tomography (F-18-FDG…”
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Impaired Pten expression in human malignant peripheral nerve sheath tumours by Bradtmöller, Maren, Hartmann, Christian, Zietsch, Jan, Jäschke, Sebastian, Mautner, Victor-F, Kurtz, Andreas, Park, Su-Jin, Baier, Michael, Harder, Anja, Reuss, David, von Deimling, Andreas, Heppner, Frank L, Holtkamp, Nikola

“…Malignant peripheral nerve sheath tumours (MPNST) are aggressive sarcomas that develop in about 10% of patients with the genetic disease neurofibromatosis type…”
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EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy by Holtkamp, Nikola, Malzer, Elke, Zietsch, Jan, Okuducu, Ali Fuat, Mucha, Jana, Mawrin, Christian, Mautner, Victor-F, Schildhaus, Hans-Ulrich, von Deimling, Andreas

“…Malignant peripheral nerve sheath tumors (MPNSTs) are sarcomas with poor prognosis and limited treatment options. Evidence for a role of epidermal growth…”
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Nilotinib is more potent than imatinib for treating plexiform neurofibroma in vitro and in vivo by Wei, Jiang, Freytag, Marcus, Schober, Yvonne, Nockher, Wolfgang A, Mautner, Victor F, Friedrich, Reinhard E, Manley, Paul W, Kluwe, Lan, Kurtz, Andreas

“…Plexiform neurofibromas (PNFs) are benign nerve sheath tumors mostly associated with neurofibromatosis type 1. They often extend through multiple layers of…”
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Testing ATRA and MEK inhibitor PD0325901 effectiveness in a nude mouse model for human MPNST xenografts by Fischer-Huchzermeyer, Susan, Chikobava, Levan, Stahn, Verena, Zangarini, Monique, Berry, Philip, Veal, Gareth J, Senner, Volker, Mautner, Victor F, Harder, Anja

“…Malignant peripheral nerve sheath tumors (MPNST) are aggressive sarcomas characterized by high recurrence rates and early metastases. These tumors arise more…”
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Effects of splicing mutations on NF2-transcripts: Transcript analysis and information theoretic predictions by Ellis Jr, James R., Heinrich, Bianca, Mautner, Victor-F., Kluwe, Lan

“…This study examined the effects of 22 putative splicing mutations in the NF2 gene by means of transcript analysis and information theory based prediction…”
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Double NF1 inactivation affects adrenocortical function in NF1Prx1 mice and a human patient by Kobus, Karolina, Hartl, Daniela, Ott, Claus Eric, Osswald, Monika, Huebner, Angela, von der Hagen, Maja, Emmerich, Denise, Kühnisch, Jirko, Morreau, Hans, Hes, Frederik J, Mautner, Victor F, Harder, Anja, Tinschert, Sigrid, Mundlos, Stefan, Kolanczyk, Mateusz

“…Neurofibromatosis type I (NF1, MIM#162200) is a relatively frequent genetic condition, which predisposes to tumor formation. Apart from tumors, individuals…”
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Imatinib mesylate (Glivec) inhibits Schwann cell viability and reduces the size of human plexiform neurofibroma in a xenograft model by Demestre, Maria, Herzberg, Jan, Holtkamp, Nikola, Hagel, Christian, Reuss, David, Friedrich, Reinhard E., Kluwe, Lan, Von Deimling, Andreas, Mautner, Victor-F., Kurtz, Andreas

“…Plexiform neurofibromas (PNF), one of the major features of neurofibromatosis type 1 (NF1), are characterized by complex cellular composition and mostly slow…”
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Preclinical assessment of the anticancer drug response of plexiform neurofibroma tissue using primary cultures by Jiang, Wei, Mautner, Victor F, Friedrich, Reinhard E, Kluwe, Lan

“…Individualized drug testing for tumors using a strategy analogous to antibiotic tests for infectious diseases would be highly desirable for personalized and…”
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Mutations in the LGI1/Epitempin gene on 10q24 cause autosomal dominant lateral temporal epilepsy by Morante-Redolat, José M., Gorostidi-Pagola, Ana, Piquer-Sirerol, Salomé, Sáenz, Amets, Poza, Juan J., Galán, Juan, Gesk, Stefan, Sarafidou, Theologia, Mautner, Victor-F., Binelli, Simona, Staub, Eike, Hinzmann, Bernd, French, Lisa, Prud'homme, Jean-F., Passarelli, Daniela, Scannapieco, Paolo, Tassinari, Carlo A., Avanzini, Giuliano, Martí-Massó, José F., Kluwe, Lan, Deloukas, Panagiotis, Moschonas, Nicholas K., Michelucci, Roberto, Siebert, Reiner, Nobile, Carlo, Pérez-Tur, Jordi, López de Munain, Adolfo

“…Autosomal dominant lateral temporal epilepsy (EPT; OMIM 600512) is a form of epilepsy characterized by partial seizures, usually preceded by auditory signs…”
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Mutation and expression of PDGFRA and KIT in malignant peripheral nerve sheath tumors, and its implications for imatinib sensitivity by Holtkamp, Nikola, Okuducu, Ali Fuat, Mucha, Jana, Afanasieva, Anastasia, Hartmann, Christian, Atallah, Isis, Estevez-Schwarz, Lope, Mawrin, Christian, Friedrich, Reinhard E., Mautner, Victor-F., von Deimling, Andreas

“…Platelet-derived growth factor receptor alpha (PDGFRα) and c-Kit are receptor tyrosine kinases. Both are targets of the tyrosine kinase inhibitor imatinib…”
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Ral Overactivation in Malignant Peripheral Nerve Sheath Tumors by Bodempudi, Vidya, Yamoutpoor, Farnaz, Pan, Weihong, Dudek, Arkadiusz Z., Esfandyari, Tuba, Piedra, Mark, Babovick-Vuksanovic, Dusica, Woo, Richard A., Mautner, Victor F., Kluwe, Lan, Clapp, D. Wade, De Vries, George H., Thomas, Stacey L., Kurtz, Andreas, Parada, Luis F., Farassati, Faris

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Impairment of Procedural Learning and Motor Intracortical Inhibition in Neurofibromatosis Type 1 Patients by Zimerman, Máximo, Wessel, Maximilian J., Timmermann, Jan E., Granström, Sofia, Gerloff, Christian, Mautner, Victor F., Hummel, Friedhelm C.

“…Cognitive difficulties are the most common neurological complications in neurofibromatosis type 1 (NF1) patients. Recent animal models proposed increased…”
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Constitutional NF1 mutations in neurofibromatosis 1 patients with malignant peripheral nerve sheath tumors by Kluwe, Lan, Friedrich, Reinhard E., Peiper, Matthias, Friedman, Jan, Mautner, Victor-F.

“…Neurofibromatosis type 1 (NF1) patients have 10% of lifetime risk for developing malignant peripheral nerve sheath tumors (MPNST), one of the most aggressive…”
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