Search Results - "MAULDIN, S. C"

The Total Synthesis of Lipid I by VanNieuwenhze, Michael S, Mauldin, Scott C, Zia-Ebrahimi, Mohammad, Aikins, James A, Blaszczak, Larry C

“…A total synthesis of lipid I (4), a membrane-associated intermediate in the bacterial cell wall (peptidoglycan) biosynthesis pathway, is reported. This highly…”
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Inhibition of human leukocyte elastase (HLE) by N-substituted peptidyl trifluoromethyl ketones by Skiles, Jerry W, Fuchs, Victor, Miao, Clara, Sorcek, Ronald, Grozinger, Karl G, Mauldin, Scott C, Vitous, Jana, Mui, Philip W, Jacober, Stephen

“…A series of tripeptides possessing trifluoromethyl or aryl ketone residues at P1 were prepared and evaluated both in vitro and in vivo as potential inhibitors…”
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Synthesis and antiviral activity of prodrugs of the nucleoside 1-[2′,3′-Dideoxy-3′-C-(hydroxymethyl)-β- d-erythropentofuranosyl] cytosine by Mauldin, Scott C., Paget Jr, C.J., Jones, C.David, Colacino, Joseph M., Baxter, Angela J., Staschke, Kirk A., Johansson, Nils-Gunnar, Vrang, Lotta

“…The synthesis and antiviral evaluation of 21 prodrugs of 1-[2′,3′-dideoxy-3′-C-(hydroxymethyl)-β- d-erythropentofuranosyl] cytosine 1 is reported. Cytosine N…”
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Synthesis of C-3 side-chain carboxylic acid cannabinoid derivatives by Borne, Ronald F., Mauldin, Scott C.

“…Based upon the structural similarities of cannabinoid derivatives which inhibit the biosynthesis of prostaglandins with those of the potent inhibitor,…”
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Novel non-nucleoside inhibitors of HIV-1 reverse transcriptase. 1. Tricyclic pyridobenzo- and dipyridodiazepinones by Hargrave, Karl D, Proudfoot, John R, Grozinger, Karl G, Cullen, Ernest, Kapadia, Suresh R, Patel, Usha R, Fuchs, Victor U, Mauldin, Scott C, Vitous, Jana

“…Novel pyrido[2,3-b][1,4]benzodiazepinones (I), pyrido[2,3-b][1,5]benzodiazepinones (II), and dipyrido[3,2-b:2',3'-e][1,4]diazepinones (III) were found to…”
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The First Total Synthesis of Lipid II:  The Final Monomeric Intermediate in Bacterial Cell Wall Biosynthesis by VanNieuwenhze, Michael S, Mauldin, Scott C, Zia-Ebrahimi, Mohammad, Winger, Brian E, Hornback, William J, Saha, Shankar L, Aikins, James A, Blaszczak, Larry C

“…Bacterial peptidoglycan is composed of a network of β-[1,4]-linked glyan strands that are cross-linked through pendant peptide chains. The final product, the…”
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Novel non-nucleoside inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. IV: 2-substituted dipyridodiazepinones as potent inhibitors of both wild-type and cysteine-181 HIV-1 reverse transcriptase enzymes by PROUDFOOT, J. R, HARGRAVE, K. D, ROSE, J, DAVID, E, MAULDIN, S. C, FUCHS, V. U, VITOUS, J, HOERMANN, M, KLUNDER, J. M, PALAYAKOTAI RAGHAVAN, SKILES, J. W, MUI, P, KAPADIA, S. R, RICHMAN, D. D, SULLIVAN, J. L, CHENG-KON SHIH, GROB, P. M, ADAMS, J, PATEL, U. R, GROZINGER, K. G, MCNEIL, D. W, CULLEN, E, CARDOZO, M, LIANG TONG, KELLY, T. A

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Novel non-nucleoside inhibitors of HIV-1 reverse transcriptase. I, Tricyclic pyridobenzo- and dipyridodiazepinones by HARGRAVE, K. D, PROUDFOOT, J. R, KLUNDER, J. M, PAL, K, SKILES, J. W, MCNEIL, D. W, ROSE, J. M, CHOW, G. C, SKOOG, M. T, WU, J. C, SCHMIDT, G, ENGEL, W. W, GROZINGER, K. G, CULLEN, E, KAPADIA, S. R, PATEL, U. R, FUCHS, V. U, MAULDIN, S. C, VITOUS, J, BEHNKE, M. L

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