Search Results - "MAUCH, C"

How to reduce parental provision of unhealthy foods to 3‐ to 8‐year‐old children in the home environment? A systematic review utilizing the Behaviour Change Wheel framework by Johnson, B. J., Zarnowiecki, D., Hendrie, G. A., Mauch, C. E., Golley, R. K.

“…Summary Background and objective The effectiveness of obesity prevention interventions to improve children's diet can be enhanced. Deconstructing past…”
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Treatment‐specific evaluation of the modified Glasgow‐Prognostic‐Score in patients with advanced cutaneous melanoma by Pflug, N., Vitus, M., Knuever, J., Hamacher, S., Mauch, C., Schlaak, M., Theurich, S.

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The fibronectin/α3β1 integrin axis serves as molecular basis for keratinocyte invasion induced by βHPV by Heuser, S, Hufbauer, M, Steiger, J, Marshall, J, Sterner-Kock, A, Mauch, C, Zigrino, P, Akgül, B

“…Organ-transplant-recipients exhibit cancerization of the skin from which multiple human papillomavirus (HPV)-positive squamous cell carcinomas (SCCs) arise…”
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Deletion of ADAM-9 in HGF/CDK4 mice impairs melanoma development and metastasis by Giebeler, N, Schönefuß, A, Landsberg, J, Tüting, T, Mauch, C, Zigrino, P

“…ADAM-9 is a metalloproteinase expressed in peritumoral areas by invading melanoma cells and by adjacent peritumoral stromal cells; however, its function in…”
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The fibronectin/ alpha 3 beta 1 integrin axis serves as molecular basis for keratinocyte invasion induced by beta HPV by Heuser, S, Hufbauer, M, Steiger, J, Marshall, J, Sterner-Kock, A, Mauch, C, Zigrino, P, Akguel, B

“…Organ-transplant-recipients exhibit cancerization of the skin from which multiple human papillomavirus (HPV)-positive squamous cell carcinomas (SCCs) arise…”
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Extended surgical safety margins and ulceration are associated with an improved prognosis in pleomorphic dermal sarcomas by Persa, O.D., Loquai, C., Wobser, M., Baltaci, M., Dengler, S., Kreuter, A., Volz, A., Laimer, M., Emberger, M., Doerler, M., Mauch, C., Helbig, D.

“…Background Pleomorphic dermal sarcomas (PDS) are frequent UV‐induced sarcomas of the skin of intermediate grade malignant potential. Despite the fact that PDS…”
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Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential by De Craene, B, Denecker, G, Vermassen, P, Taminau, J, Mauch, C, Derore, A, Jonkers, J, Fuchs, E, Berx, G

“…Expression of the EMT-inducing transcription factor Snail is enhanced in different human cancers. To investigate the in vivo role of Snail during progression…”
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Paclitaxel with or without trametinib or pazopanib in advanced wild-type BRAF melanoma (PACMEL): a multicentre, open-label, randomised, controlled phase II trial by Urbonas, V., Schadendorf, D., Zimmer, L., Danson, S., Marshall, E., Corrie, P., Wheater, M., Plummer, E., Mauch, C., Scudder, C., Goff, M., Love, S.B., Mohammed, S.B., Middleton, M.R.

“…Advanced melanoma treatments often rely on immunotherapy or targeting mutations, with few treatment options for wild-type BRAF (BRAF-wt) melanoma. However, the…”
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Correlation of Merkel cell polyomavirus positivity with PDGFRα mutations and survivin expression in Merkel cell carcinoma by Batinica, M, Akgül, B, Silling, S, Mauch, C, Zigrino, P

“…Highlights • Polyomavirus positivity or integration do not correlate to disease outcome. • Higher viral load are associated with progressive disease,…”
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Prolonged fear incubation leads to generalized avoidance behavior in mice by Pamplona, F.A, Henes, K, Micale, V, Mauch, C.P, Takahashi, R.N, Wotjak, C.T

“…Abstract Long-lasting presence of avoidance and emotional numbing are reliable behavioral markers for PTSD, but little is known about its psychological and…”
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Patient perception of the benefit of a BRAF inhibitor in metastatic melanoma: quality-of-life analyses of the BREAK-3 study comparing dabrafenib with dacarbazine by Grob, J.-J., Amonkar, M.M., Martin-Algarra, S., Demidov, L.V., Goodman, V., Grotzinger, K., Haney, P., Kämpgen, E., Karaszewska, B., Mauch, C., Miller, W.H., Millward, M., Mirakhur, B., Rutkowski, P., Chiarion-Sileni, V., Swann, S., Hauschild, A.

“…In a randomized phase III study (BREAK-3), dabrafenib showed prolonged progression-free survival (PFS) (median 5.1 versus 2.7 months; hazard ratio = 0.30; 95%…”
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Tumor–stroma interactions: their role in the control of tumor cell invasion by Zigrino, P., Löffek, S., Mauch, C.

“…The development and progression of tumors result from the concerted activity not only of tumor cells with neighboring cells e.g., fibroblasts and inflammatory…”
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Versatile Emulation of Spiking Neural Networks on an Accelerated Neuromorphic Substrate by Billaudelle, S., Stradmann, Y., Schreiber, K., Cramer, B., Baumbach, A., Dold, D., Goltz, J., Kungl, A. F., Wunderlich, T. C., Hartel, A., Muller, E., Breitwieser, O., Mauch, C., Kleider, M., Grubl, A., Stockel, D., Pehle, C., Heimbrecht, A., Spilger, P., Kiene, G., Karasenko, V., Senn, W., Petrovici, M. A., Schemmel, J., Meier, K.

“…We present first experimental results on the novel BrainScaleS-2 neuromorphic architecture based on an analog neuro-synaptic core and augmented by embedded…”
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Haem oxygenase-1: a novel player in cutaneous wound repair and psoriasis? by Hanselmann, C, Mauch, C, Werner, S

“…Haem oxygenase (HO) is the rate-limiting enzyme in the degradation of haem. In addition to its obvious role in iron metabolism, a series of findings indicate…”
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MGMT gene promoter methylation correlates with tolerance of temozolomide treatment in melanoma but not with clinical outcome by Hassel, J C, Sucker, A, Edler, L, Kurzen, H, Moll, I, Stresemann, C, Spieth, K, Mauch, C, Rass, K, Dummer, R, Schadendorf, D

“…Background: Despite limited clinical efficacy, treatment with dacarbazine or temozolomide (TMZ) remains the standard therapy for metastatic melanoma. In…”
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The telomere profile distinguishes two classes of genetically distinct cutaneous squamous cell carcinomas by Leufke, C, Leykauf, J, Krunic, D, Jauch, A, Holtgreve-Grez, H, Böhm-Steuer, B, Bröcker, E-B, Mauch, C, Utikal, J, Hartschuh, W, Purdie, K J, Boukamp, P

“…The incidence of skin cancer is increasing worldwide and cutaneous squamous cell carcinomas (SCCs) are associated with considerable morbidity and mortality,…”
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Assessment of clinical parameters associated with mutational status in metastatic malignant melanoma: a single-centre investigation of 141 patients by Schlaak, M., Bajah, A., Podewski, T., Kreuzberg, N., von Bartenwerffer, W., Wardelmann, E., Merkelbach-Bruse, S., Büttner, R., Mauch, C., Kurschat, P.

“…Summary Background  Inhibitors of the mutated, constitutively activated BRAF protein have shown efficacy in the treatment of metastatic melanoma in clinical…”
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Reply to Rituxan is not associated with Stevens–Johnson syndrome by Parise, L., Kahle, J., Schlaak, M., Mauch, C., Kurschat, P.

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Sorafenib and pegylated interferon-α2b in advanced metastatic melanoma: a multicenter phase II DeCOG trial by Egberts, F., Gutzmer, R., Ugurel, S., Becker, J.C., Trefzer, U., Degen, A., Schenck, F., Frey, L., Wilhelm, T., Hassel, J.C., Schadendorf, D., Livingstone, E., Mauch, C., Garbe, C., Berking, C., Rass, K., Mohr, P., Kaehler, K.C., Weichenthal, M., Hauschild, A.

“…The combination of sorafenib, a multikinase inhibitor, and pegylated interferon-α2b (Peg-IFN-α2b) could potentially lead to an improved antitumoral response…”
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Novel roles of NM23 proteins in skin homeostasis, repair and disease by BRAUN, S, MAUCH, C, BOUKAMP, P, WERNER, S

“…Keratinocyte growth factor (KGF) is an important regulator of epidermal homeostasis and repair. Therefore, the identification of KGF target genes in…”
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