Search Results - "MATUSCHEWSKI, Kai"
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Cytokines and Chemokines in Cerebral Malaria Pathogenesis
Published in Frontiers in cellular and infection microbiology (20-07-2017)“…Cerebral malaria is among the major causes of malaria-associated mortality and effective adjunctive therapeutic strategies are currently lacking. Central…”
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Of membranes and malaria: phospholipid asymmetry in Plasmodium falciparum-infected red blood cells
Published in Cellular and molecular life sciences : CMLS (01-05-2021)“…Malaria is a vector-borne parasitic disease with a vast impact on human history, and according to the World Health Organisation, Plasmodium parasites still…”
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In memoriam: Theodor Hiepe (1929–2022)—great German scholar of parasitology
Published in Parasitology research (1987) (01-04-2023)“…Theodor Hiepe (1929-2022) was an outstanding researcher, a world-renowned scientist, a dedicated teacher and a great mentor. During his scientific career,…”
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Getting infectious: formation and maturation of Plasmodium sporozoites in the Anopheles vector
Published in Cellular microbiology (01-10-2006)“…Summary Research on Plasmodium sporozoite biology aims at understanding the developmental program steering the formation of mature infectious sporozoites – the…”
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Cell biology and immunology of malaria
Published in Immunological reviews (01-03-2011)“…Malaria is a vector-borne infectious disease caused by unicellular parasites of the genus Plasmodium. These obligate intracellular parasites have the unique…”
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Arrested Oocyst Maturation in Plasmodium Parasites Lacking Type II NADH:Ubiquinone Dehydrogenase
Published in The Journal of biological chemistry (16-09-2011)“…The Plasmodium mitochondrial electron transport chain has received considerable attention as a potential target for new antimalarial drugs. Atovaquone, a…”
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High diversity of West African bat malaria parasites and a tight link with rodent Plasmodium taxa
Published in Proceedings of the National Academy of Sciences - PNAS (22-10-2013)“…As the only volant mammals, bats are captivating for their high taxonomic diversity, for their vital roles in ecosystems—particularly as pollinators and…”
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Molecular characterization of Schellackia parasites in an urban population of sand lizards (Lacerta agilis) from Berlin, Germany
Published in Parasitology research (1987) (01-08-2023)“…Lizards are hosts of several taxa of unicellular parasites of the phylum Apicomplexa, including Karyolysus , Schellackia , Lankesterella, and Hepatozoon …”
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The Liver-Stage Plasmodium Infection Is a Critical Checkpoint for Development of Experimental Cerebral Malaria
Published in Frontiers in immunology (01-11-2019)“…Cerebral malaria is a life-threatening complication of malaria in humans, and the underlying pathogenic mechanisms are widely analyzed in a murine model of…”
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Functional profiles of orphan membrane transporters in the life cycle of the malaria parasite
Published in Nature communications (22-01-2016)“…Assigning function to orphan membrane transport proteins and prioritizing candidates for detailed biochemical characterization remain fundamental challenges…”
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The Puf-family RNA-binding protein Puf2 controls sporozoite conversion to liver stages in the malaria parasite
Published in PloS one (18-05-2011)“…Malaria is a vector-borne infectious disease caused by unicellular, obligate intracellular parasites of the genus Plasmodium. During host switch the malaria…”
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The deubiquitinating enzyme OTUD7b protects dendritic cells from TNF-induced apoptosis by stabilizing the E3 ligase TRAF2
Published in Cell death & disease (29-07-2023)“…The cytokine tumor necrosis factor (TNF) critically regulates the intertwined cell death and pro-inflammatory signaling pathways of dendritic cells (DCs) via…”
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A sporozoite asparagine-rich protein controls initiation of Plasmodium liver stage development
Published in PLoS pathogens (01-06-2008)“…Plasmodium sporozoites invade host hepatocytes and develop as liver stages (LS) before the onset of erythrocytic infection and malaria symptoms. LS are…”
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Neuropilin-1 identifies a subset of highly activated CD8+ T cells during parasitic and viral infections
Published in PLoS pathogens (01-11-2023)“…Neuropilin-1 (Nrp-1) expression on CD8+ T cells has been identified in tumor-infiltrating lymphocytes and in persistent murine gamma-herpes virus infections,…”
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The acid ceramidase/ceramide axis controls parasitemia in Plasmodium yoelii-infected mice by regulating erythropoiesis
Published in eLife (12-09-2022)“…Acid ceramidase (Ac) is part of the sphingolipid metabolism and responsible for the degradation of ceramide. As bioactive molecule, ceramide is involved in the…”
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An Unusual Prohibitin Regulates Malaria Parasite Mitochondrial Membrane Potential
Published in Cell reports (Cambridge) (17-04-2018)“…Proteins of the stomatin/prohibitin/flotillin/HfIK/C (SPFH) family are membrane-anchored and perform diverse cellular functions in different organelles. Here,…”
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Plasmodium Para-Aminobenzoate Synthesis and Salvage Resolve Avoidance of Folate Competition and Adaptation to Host Diet
Published in Cell reports (Cambridge) (08-01-2019)“…Folate metabolism is essential for DNA synthesis and a validated drug target in fast-growing cell populations, including tumors and malaria parasites. Genome…”
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Breakdown in membrane asymmetry regulation leads to monocyte recognition of P. falciparum-infected red blood cells
Published in PLoS pathogens (01-02-2021)“…The human malaria parasite Plasmodium falciparum relies on lipids to survive; this makes its lipid metabolism an attractive drug target. The lipid…”
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A Plasmodium cysteine protease required for efficient transition from the liver infection stage
Published in PLoS pathogens (21-09-2020)“…The transitions between developmental stages are critical points in the Plasmodium life cycle. The development of Plasmodium in the livers of their mammalian…”
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Plasmodium berghei Sporozoites Acquire Virulence and Immunogenicity during Mosquito Hemocoel Transit
Published in Infection and Immunity (01-03-2014)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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