Search Results - "MATTSSON, Jonas"
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Safety and Immunogenicity After a Three-Dose SARS-CoV-2 Vaccine Schedule in Allogeneic Stem Cell Transplant Recipients
Published in Transplantation and cellular therapy (01-10-2022)“…In allogeneic stem cell transplant (Allo-SCT) recipients, the cell-mediated and humoral immunogenicity of the 3-dose SARS-CoV-2 vaccination schedule has not…”
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2
CAR T cells and T cells phenotype and function are impacted by glucocorticoid exposure with different magnitude
Published in Journal of translational medicine (12-03-2024)“…Chimeric antigen receptor (CAR) T cell therapy is associated with high risk of adverse events. Glucocorticoids (GCs) are cornerstone in the management of…”
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3
Risk factors for Epstein-Barr virus-related post-transplant lymphoproliferative disease after allogeneic hematopoietic stem cell transplantation
Published in Haematologica (Roma) (01-02-2014)“…Allogeneic hematopoietic stem cell transplantation is a successful treatment for hematologic malignancies and a variety of genetic and metabolic disorders. In…”
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4
Population-based real-world registry study to evaluate clinical outcomes of chronic graft-versus-host disease
Published in PLoS biology (09-03-2023)“…Chronic graft-versus-host disease (cGVHD) is a serious immune-mediated complication after allogeneic haematopoietic stem cell transplantation (HSCT), but in…”
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5
A prospective randomized trial comparing cyclosporine/methotrexate and tacrolimus/sirolimus as graft-versus-host disease prophylaxis after allogeneic hematopoietic stem cell transplantation
Published in Haematologica (Roma) (01-11-2016)“…Improvement of graft-versus-host disease prophylaxis remains an important goal in allogeneic hematopoietic stem cell transplantation. Based on reports of…”
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6
The Metabolic Profile of Tumor and Virally Infected Cells Shapes Their Microenvironment Counteracting T Cell Immunity
Published in Frontiers in immunology (04-10-2019)“…Upon activation naïve T cells undergo metabolic changes to support the differentiation into subsets of effector or regulatory cells, and enable subsequent…”
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7
Pilot prospective study of Frailty and Functionality in routine clinical assessment in allogeneic hematopoietic cell transplantation
Published in Bone marrow transplantation (Basingstoke) (01-01-2021)“…A Frailty and Functionality evaluation for alloHCT was implemented using existing resources. We describe the implementation of this evaluation across all ages…”
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Fetal Membrane Cells for Treatment of Steroid‐Refractory Acute Graft‐Versus‐Host Disease
Published in Stem cells (Dayton, Ohio) (01-03-2013)“…The placenta protects the fetus from the mother's immune system. We have previously found that fetal membrane cells (FMCs) isolated from term placenta prevent…”
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A longitudinal multidimensional rehabilitation program for patients undergoing allogeneic blood and marrow transplantation (CaRE-4-alloBMT): Protocol for a phase II feasibility pilot randomized controlled trial
Published in PloS one (16-05-2023)“…Allogeneic blood and marrow transplantation (alloBMT) is a curative treatment for blood cancers associated with various treatment-related adverse events and…”
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10
Flavin-containing monooxygenase 3 (FMO3) role in busulphan metabolic pathway
Published in PloS one (09-11-2017)“…Busulphan (Bu) is an alkylating agent used in the conditioning regimen prior to hematopoietic stem cell transplantation (HSCT). Bu is extensively metabolized…”
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11
Tuned activation of MSLN-CAR T cells induces superior antitumor responses in ovarian cancer models
Published in Journal for immunotherapy of cancer (01-02-2023)“…BackgroundLimited persistence of functional CAR T cells in the immunosuppressive solid tumor microenvironment remains a major hurdle in the successful…”
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12
A novel CD34-specific T-cell engager efficiently depletes acute myeloid leukemia and leukemic stem cells in vitro and in vivo
Published in Haematologica (Roma) (10-02-2022)“…Less than a third of acute myeloid leukemia (AML) patients are cured by chemotherapy and/or hematopoietic stem cell transplantation (HSCT), highlighting the…”
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13
Targeting of Nrf2 improves antitumoral responses by human NK cells, TIL and CAR T cells during oxidative stress
Published in Journal for immunotherapy of cancer (01-06-2022)“…BackgroundAdoptive cell therapy using cytotoxic lymphocytes is an efficient immunotherapy against solid and hematological cancers. However, elevated levels of…”
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Clonal hematopoiesis in the donor does not adversely affect long-term outcomes following allogeneic hematopoietic stem cell transplantation: result from a 13-year follow-up
Published in Haematologica (Roma) (01-07-2023)“…Donor clonal hematopoiesis may be transferred to the recipient through allogeneic hematopoietic stem cell transplantation (HSCT), but the potential for adverse…”
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15
Trogocytosis and fratricide killing impede MSLN-directed CAR T cell functionality
Published in Oncoimmunology (2022)“…Successful translation of chimeric antigen receptor (CAR) T cell therapy for the treatment of solid tumors has proved to be troublesome, mainly due to the…”
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Respiratory Syncytial Virus Infection in Recipients of Allogeneic Stem-Cell Transplantation: A Retrospective Study of the Incidence, Clinical Features, and Outcome
Published in Transplantation (27-11-2009)“…Respiratory syncytial virus (RSV) is a common cause of serious respiratory infections in hematopoietic stem-cell transplant (HSCT) recipients. We aimed to…”
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Transplanted Bone Marrow-Derived Cells Contribute to Human Adipogenesis
Published in Cell metabolism (01-09-2015)“…Because human white adipocytes display a high turnover throughout adulthood, a continuous supply of precursor cells is required to maintain adipogenesis. Bone…”
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Long-term outcome in patients treated at home during the pancytopenic phase after allogeneic haematopoietic stem cell transplantation
Published in International journal of hematology (01-04-2018)“…Patients undergoing allogeneic haematopoietic stem cell transplantation (HSCT) were given the option to be treated at home during the pancytopenic phase. Daily…”
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19
Multicenter evaluation of parametric response mapping as an indicator of bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation
Published in American journal of transplantation (01-08-2020)“…Parametric response mapping (PRM) is a novel computed tomography (CT) technology that has shown potential for assessment of bronchiolitis obliterans syndrome…”
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Treatment of radiculomyelopathy in two patients with placenta-derived decidua stromal cells
Published in International journal of hematology (01-04-2020)“…Mesenchymal stromal cells may reverse acute inflammatory disorders. The placenta is important in feto-maternal tolerance. We have used placenta-derived decidua…”
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