Search Results - "MATTHEWS, R. C."

Pathways of Protein Folding by Matthews, C R

“…Advances in spectroscopy, protein engineering, and peptide synthesis have had a dramatic impact on the understanding of the structures and stabilities of…”
Get full text

Bordetella pertussis infection : Pathogenesis, diagnosis, management, and the role of protective immunity by KERR, J. R, MATTHEWS, R. C

“…Whooping cough is presently one of the ten most common causes of death from infectious disease worldwide. Despite a high vaccine uptake, resurgences of this…”
Get full text

Friction-Limited Folding of Disulfide-Reduced Monomeric SOD1 by Cohen, Noah R., Kayatekin, Can, Zitzewitz, Jill A., Bilsel, Osman, Matthews, C.R.

“…The folding reaction of a stable monomeric variant of Cu/Zn superoxide dismutase (mSOD1), an enzyme responsible for the conversion of superoxide free radicals…”
Get full text

Bordetella pertussis surveillance in England and Wales: 1995–7 by VAN BUYNDER, P. G., OWEN, D., VURDIEN, J. E., ANDREWS, N. J., MATTHEWS, R. C., MILLER, E.

“…Available data sources on disease due to Bordetella pertussis, including notifications, hospital admissions, deaths, and an enhanced laboratory-based…”
Get full text

Human recombinant antibody to HSP90: a natural partner in combination therapy by Matthews, R C, Burnie, J P

“…Recent years have seen the development of the concept of combination therapy for treating severe fungal sepsis. The advantages of this approach are a potential…”
Get more information

An epidemiological study of blood culture isolates of coagulase-negative staphylococci demonstrating hospital-acquired infection by BURNIE, J. P, NADERI-NASAB, M, LOUDON, K. W, MATTHEWS, R. C

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Multistate Equilibrium Unfolding of Escherichia coli Dihydrofolate Reductase:  Thermodynamic and Spectroscopic Description of the Native, Intermediate, and Unfolded Ensembles by Ionescu, Roxana M, Smith, Virginia F, O'Neil, John C, Matthews, C. Robert

“…The thermodynamic and spectroscopic properties of a cysteine-free variant of Escherichia coli dihydrofolate reductase (AS-DHFR) were investigated using the…”
Get full text

Identification of an immunodominant ABC transporter in methicillin-resistant Staphylococcus aureus infections by BURNIE, J. P, MATTHEWS, R. C, CARTER, T, BEAULIEU, E, DONOHOE, M, CHAPMAN, C, WILLIAMSON, P, HODGETTS, S. J

“…Immunoblotting sera from 26 patients with septicemia due to an epidemic strain of methicillin-resistant Staphylococcus aureus (EMRSA-15), 6 of whom died,…”
Get full text

Identification of an immunodominant drug efflux pump in Burkholderia cepacia by Wigfield, S. M., Rigg, G. P., Kavari, M., Webb, A. K., Matthews, R. C., Burnie, J. P.

“…Burkholderia cepacia, a major pathogen amongst individuals with cystic fibrosis (CF), is intrinsically resistant to most clinically available antibiotics. We…”
Get full text

The progressive development of structure and stability during the equilibrium folding of the α subunit of tryptophan synthase from Escherichia coli by GUALFETTI, PETER J., BILSEL, OSMAN, MATTHEWS, C. ROBERT

“…The urea-induced equilibrium unfolding of the α subunit of tryptophan synthase (αTS), a single domain α/β barrel protein, displays a stable intermediate at…”
Get full text

Pathogenicity determinants of Candida albicans : potential targets for immunotherapy ? by MATTHEWS, R. C

“…There are two synergistic approaches to the development of a new generation of antifungal agents. The first involves a better understanding of the pathogenesis…”
Get full text

Application of polymerase chain reaction to fingerprinting Aspergillus fumigatus by random amplification of polymorphic DNA by LOUDON, K. W, BURNIE, J. P, COKE, A. P, MATTHEWS, R. C

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Mapping the Energy Surface for the Folding Reaction of the Coiled-Coil Peptide GCN4-p1 by Ibarra-Molero, Beatriz, Makhatadze, George I, Matthews, C. Robert

“…The energy surface for the folding/unfolding reactions of the homodimeric coiled-coil peptide M2V GCN4-p1, a 33-residue segment comprising the leucine zipper…”
Get full text

Application of the polymerase chain reaction to the diagnosis of candidosis by amplification of an HSP 90 gene fragment by Crampin, A. C, Matthews, R. C

“…Department of Medical Microbiology, Manchester University Medical School, Oxford Road, Manchester M13 9PT * Correspondence should be sent to Dr R. C. Matthews…”
Get full text

Resolution of the fluorescence equilibrium unfolding profile of trp aporepressor using single tryptophan mutants by Royer, Catherine A., Mann, Craig J., Matthews, C. Robert

“…Single tryptophan mutants of the trp aporepressor, tryptophan 19 → phenylalanine (W19F) and tryptophan 99 → phenylalanine (W99F), were used in this study to…”
Get full text

Autoantibody to heat-shock protein 90 can mediate protection against systemic candidosis by MATTHEWS, R. C, BURNIE, J. P, HOWAT, D, ROWLAND, T, WALTON, F

“…Epitope mapping shows that patients recovering from systemic infection with Candida albicans produce antibodies against both fungal-specific and conserved…”
Get full text

Detection of a Stable Intermediate in the Thermal Unfolding of a Cysteine-Free Form of Dihydrofolate Reductase from Escherichia Coli by Luo, J, Iwakura, M, Matthews, C. R

“…The reversible temperature-induced unfolding of a cysteine-free mutant (C85S/C152E, des-Cys) of dihydrofolate reductase from Escherichia coli has been studied…”
Get full text

Identifying the structural boundaries of independent folding domains in the α subunit of tryptophan synthase, a β/α barrel protein by ZITZEWITZ, JILL A., GUALFETTI, PETER J., PERKONS, IEVA A., WASTA, STACEY A., MATTHEWS, C. ROBERT

“…Two equilibrium intermediates have previously been observed in the urea denaturation of the α subunit of tryptophan synthase (αTS) from Escherichia coli, an…”
Get full text

Probing minimal independent folding units in dihydrofolate reductase by molecular dissection by Gegg, Colin V., Bowers, Katherine E., Matthews, C. Robert

“…Molecular dissection was employed to identify minimal independent folding units in dihydrofolate reductase (DHFR) from Escherichia coli. Eight overlapping…”
Get full text

Isolation of immunodominant antigens from sera of patients with systemic candidiasis and characterization of serological response to Candida albicans by MATTHEWS, R. C, BURNIE, J. P, TABAQCHALI, S

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text