Search Results - "MATTEI, Daniele"
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1
Neuronal activity increases translocator protein (TSPO) levels
Published in Molecular psychiatry (01-06-2021)“…The mitochondrial protein, translocator protein (TSPO), is a widely used biomarker of neuroinflammation, but its non-selective cellular expression pattern…”
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2
Enzymatic Dissociation Induces Transcriptional and Proteotype Bias in Brain Cell Populations
Published in International journal of molecular sciences (26-10-2020)“…Different cell isolation techniques exist for transcriptomic and proteotype profiling of brain cells. Here, we provide a systematic investigation of the…”
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3
A novel murine model to study the impact of maternal depression and antidepressant treatment on biobehavioral functions in the offspring
Published in Molecular psychiatry (01-11-2021)“…Antenatal psychopathology negatively affects obstetric outcomes and exerts long-term consequences on the offspring’s wellbeing and mental health. However, the…”
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4
Cytokine levels in the blood may distinguish suicide attempters from depressed patients
Published in Brain, behavior, and immunity (01-02-2011)“…Abstract Elevated plasma cytokines is a common finding in Major Depressive Disorder (MDD), although not consistent. It is currently not known whether the…”
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Symptomatic and preventive effects of the novel phosphodiesterase-9 inhibitor BI 409306 in an immune-mediated model of neurodevelopmental disorders
Published in Neuropsychopharmacology (New York, N.Y.) (01-07-2021)“…BI 409306, a phosphodiesterase-9 inhibitor under development for treatment of schizophrenia and attenuated psychosis syndrome (APS), promotes synaptic…”
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6
Philadelphia-like acute lymphoblastic leukemia is associated with minimal residual disease persistence and poor outcome. First report of the minimal residual disease-oriented GIMEMA LAL1913
Published in Haematologica (Roma) (01-06-2021)“…Early recognition of Ph-like acute lymphoblastic leukemia cases could impact on the management and outcome of this subset of B-lineage ALL. To assess the…”
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7
Basic Concept of Microglia Biology and Neuroinflammation in Relation to Psychiatry
Published in Current topics in behavioral neurosciences (01-01-2020)“…The hypothesis that the neuroimmune system plays a role in the pathogenesis of different psychiatric disorders, including schizophrenia, depression, and…”
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8
Clinical features of pulmonary arterial hypertension in patients receiving dasatinib
Published in American journal of hematology (01-11-2015)“…The prognosis of most leukemia patients treated with BCR‐ABL tyrosine kinase inhibitors (TKIs) is favorable, and a more precise understanding of serious and…”
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9
Improved risk classification for risk-specific therapy based on the molecular study of minimal residual disease (MRD) in adult acute lymphoblastic leukemia (ALL)
Published in Blood (30-04-2009)“…Clinical risk classification is inaccurate in predicting relapse in adult patients with acute lymphoblastic leukemia, sometimes resulting in patients receiving…”
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10
Chemotherapy-Phased Imatinib Pulses Improve Long-Term Outcome of Adult Patients With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Northern Italy Leukemia Group Protocol 09/00
Published in Journal of clinical oncology (01-08-2010)“…Short imatinib pulses were added to chemotherapy to improve the long-term survival of adult patients with Philadelphia chromosome (Ph) -positive acute…”
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11
Updated risk-oriented strategy for acute lymphoblastic leukemia in adult patients 18–65 years: NILG ALL 10/07
Published in Blood cancer journal (New York) (13-11-2020)“…An updated strategy combining pediatric-based chemotherapy with risk-oriented allogeneic hematopoietic cell transplantation (HCT) was evaluated in Philadelphia…”
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12
Analyses of circRNA Expression throughout the Light-Dark Cycle Reveal a Strong Regulation of Cdr1as, Associated with Light Entrainment in the SCN
Published in International journal of molecular sciences (15-10-2022)“…Circular RNAs (circRNAs) are a large class of relatively stable RNA molecules that are highly expressed in animal brains. Many circRNAs have been associated…”
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13
TYROBP/DAP12 knockout in Huntington's disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterioration
Published in Journal of neuroinflammation (08-03-2024)“…Huntington's disease (HD) is a fatal neurodegenerative disorder caused by an expansion of the CAG trinucleotide repeat in the Huntingtin gene (HTT). Immune…”
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14
Adolescence is a sensitive period for prefrontal microglia to act on cognitive development
Published in Science advances (04-03-2022)“…The prefrontal cortex (PFC) is a cortical brain region that regulates various cognitive functions. One distinctive feature of the PFC is its protracted…”
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15
A CRISPR-Cas9–engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions
Published in Proceedings of the National Academy of Sciences - PNAS (12-01-2021)“…Pathogenic germline mutations in PIGV lead to glycosylphosphatidylinositol biosynthesis deficiency (GPIBD). Individuals with pathogenic biallelic mutations in…”
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16
Clinical significance of chromatin-spliceosome acute myeloid leukemia: a report from the Northern Italy Leukemia Group (NILG) randomized trial 02/06
Published in Haematologica (Roma) (27-08-2020)“…Secondary acute myeloid leukemia (sAML) after myelodysplastic or myeloproliferative disorders is a high-risk category currently identified by clinical history…”
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Immunoglobulin M (IgM) multiple myeloma versus Waldenström macroglobulinemia: diagnostic challenges and therapeutic options: two case reports
Published in Journal of medical case reports (22-06-2020)“…Immunoglobulin M multiple myeloma and Waldenström macroglobulinemia are two different hematological diseases with the common finding of an immunoglobulin M…”
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Nonmyeloablative allografting for newly diagnosed multiple myeloma: the experience of the Gruppo Italiano Trapianti di Midollo
Published in Blood (02-04-2009)“…Despite recent advances, allografting remains the only potential cure for myeloma. From July 1999 to June 2005, 100 newly diagnosed patients younger than 65…”
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19
Randomized trial of radiation-free central nervous system prophylaxis comparing intrathecal triple therapy with liposomal cytarabine in acute lymphoblastic leukemia
Published in Haematologica (Roma) (01-06-2015)“…Developing optimal radiation-free central nervous system prophylaxis is a desirable goal in acute lymphoblastic leukemia, to avoid the long-term toxicity…”
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20
High cure rates in Burkitt lymphoma and leukemia: a Northern Italy Leukemia Group study of the German short intensive rituximab-chemotherapy program
Published in Haematologica (Roma) (01-11-2013)“…We evaluate the long-term results of a prospective clinical study enrolling more than 100 adult patients with Burkitt lymphoma/leukemia. Depending on extent of…”
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