Search Results - "MATTA, Hittu"

Narciclasine, an isocarbostyril alkaloid, has preferential activity against primary effusion lymphoma by Gopalakrishnan, Ramakrishnan, Matta, Hittu, Choi, Sunju, Chaudhary, Preet M.

“…Primary effusion lymphoma (PEL) is a subtype of non-Hodgkin lymphoma associated with infection by Kaposi sarcoma-associated herpes virus (KSHV). PEL is an…”
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A novel thermostable beetle luciferase based cytotoxicity assay by Choi, Sunju, Matta, Hittu, Gopalakrishnan, Ramakrishnan, Natarajan, Venkatesh, Gong, Songjie, Jeronimo, Alberto, Kuo, Wei-Ying, Bravo, Bryant, Chaudhary, Preet M.

“…Cytotoxicity assays are essential for the testing and development of novel immunotherapies for the treatment of cancer. We recently described a novel…”
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Development and characterization of a novel luciferase based cytotoxicity assay by Matta, Hittu, Gopalakrishnan, Ramakrishnan, Choi, Sunju, Prakash, Rekha, Natarajan, Venkatesh, Prins, Ruben, Gong, Songjie, Chitnis, Saurabh D., Kahn, Michael, Han, Xu, Chaudhary, Vishan, Soni, Adam, Sernas, Jennifer, Khan, Prottasha, Wang, Dan, Chaudhary, Preet M.

“…A simple, accurate, sensitive and robust assay that can rapidly and specifically measure the death of target cells would have applications in many areas of…”
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A Fast and Sensitive Luciferase-based Assay for Antibody Engineering and Design of Chimeric Antigen Receptors by Natarajan, Venkatesh, Gopalakrishnan, Ramakrishnan, Matta, Hittu, Choi, Sunju, Gong, Songjie, Jeronimo, Alberto, Keerthipati, Pooja Smruthi, Morales, Anthony, Venkatesh, Harishwar, Chaudhary, Preet M.

“…Success of immunotherapeutic approaches using genetically engineered antibodies and T cells modified with chimeric antigen receptors (CARs) depends, among…”
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Use of adeno-associated viral vector for delivery of small interfering RNA by TOMAR, Raghuvir S, MATTA, Hittu, CHAUDHARY, Preet M

“…Post-transcriptional gene silencing by small interfering RNAs (siRNAs) is rapidly becoming a powerful tool for genetic analysis of mammalian cells. Delivery of…”
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Activation of Alternative NF-κB Pathway by Human Herpes Virus 8-Encoded Fas-Associated Death Domain-Like IL-1β-Converting Enzyme Inhibitory Protein (vFLIP) by Matta, Hittu, Chaudhary, Preet M., Olson, Eric N.

“…The Kaposi's sarcoma-associated herpesvirus (KSHV, also called human herpesvirus 8) has been linked to KS and primary effusion lymphoma (PEL) in…”
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A novel luciferase-based assay for the detection of Chimeric Antigen Receptors by Gopalakrishnan, Ramakrishnan, Matta, Hittu, Choi, Sunju, Natarajan, Venkatesh, Prins, Ruben, Gong, Songjie, Zenunovic, Arta, Narasappa, Nell, Patel, Fatima, Prakash, Rekha, Chaudhary, Vishan, Sikri, Varun, Chitnis, Saurabh Deepak, Kochegarov, Andrei, Wang, Dan, Falat, Magdalena, Kahn, Michael, Keerthipati, Pooja Smruthi, Sharma, Naman, Lenka, Jyotirmayee, Stieben, Tomas Meza, Braun, Jason, Batra, Ankita, Purvis, Katelyn, Ito, Kenta, Lee, Jae Han, Jeronimo, Alberto, Zamora, Hannalei Mae, Membreno, Allen, Qiu, Queenie, Peshin, Supriya, Namburu, Lalith, Chaudhary, Preet M.

“…Chimeric Antigen Receptor-T (CAR-T) cell immunotherapy has produced dramatic responses in hematologic malignancies. One of the challenges in the field is the…”
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Kaposi's Sarcoma-Associated Herpesvirus Oncoprotein K13 Protects against B Cell Receptor-Induced Growth Arrest and Apoptosis through NF-κB Activation by Graham, Ciaren, Matta, Hittu, Yang, Yanqiang, Yi, Han, Suo, Yulan, Tolani, Bhairavi, Chaudhary, Preet M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC by Matta, Hittu, Gopalakrishnan, Ramakrishnan, Graham, Ciaren, Tolani, Bhairavi, Khanna, Akshat, Yi, Han, Suo, Yulan, Chaudhary, Preet M

“…Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein (vFLIP) K13 activates the NF-κB pathway by binding to the NEMO/IKKγ subunit of…”
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A computational profiling of changes in gene expression and transcription factors induced by vFLIP K13 in primary effusion lymphoma by Punj, Vasu, Matta, Hittu, Chaudhary, Preet M

“…Infection with Kaposi's sarcoma associated herpesvirus (KSHV) has been linked to the development of primary effusion lymphoma (PEL), a rare lymphoproliferative…”
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X-Linked Ectodermal Dysplasia Receptor Is Downregulated in Breast Cancer via Promoter Methylation by PUNJ, Vasu, MATTA, Hittu, CHAUDHARY, Preet M

“…Purpose: The X-linked ectodermal dysplasia receptor (XEDAR) is a novel receptor of the tumor necrosis factor receptor family that binds to ectodysplasin-A2…”
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Constitutive NF-κB Activation, Normal Fas-Induced Apoptosis, and Increased Incidence of Lymphoma in Human Herpes Virus 8 K13 Transgenic Mice by Chugh, Priti, Matta, Hittu, Schamus, Sandra, Zachariah, Sunny, Kumar, Arvind, Richardson, James A., Smith, Alice L., Chaudhary, Preet M., Gallo, Robert C.

“…Human herpesvirus 8 (HHV-8, also called Kaposi's sarcoma-associated herpes virus) has been linked to Kaposi's sarcoma and primary effusion lymphoma…”
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The proteasome inhibitor bortezomib (PS-341) inhibits growth and induces apoptosis in primary effusion lymphoma cells by Matta, Hittu, Chaudhary, Preet M.

“…The ubiquitin-proteasome pathway is responsible for degrading many critical regulatory proteins involved in immune and inflammatory responses, control of cell…”
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K13 blocks KSHV lytic replication and deregulates vIL6 and hIL6 expression: a model of lytic replication induced clonal selection in viral oncogenesis by Zhao, Jinshun, Punj, Vasu, Matta, Hittu, Mazzacurati, Lucia, Schamus, Sandra, Yang, Yanqiang, Yang, Tianbing, Hong, Yan, Chaudhary, Preethello M

“…Accumulating evidence suggests that dysregulated expression of lytic genes plays an important role in KSHV (Kaposi's sarcoma associated herpesvirus)…”
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Loss of expression of death-inducing signaling complex (DISC) components in lung cancer cell lines and the influence of MYC amplification by SHIVAPURKAR, Narayan, REDDY, Jyotsna, MATTA, Hittu, SATHYANARAYANA, Ubaradka G, HUANG, C. X, TOYOOKA, Shinichi, MINNA, John D, CHAUDHARY, Preet M, GAZDAR, Adi F

“…We have previously reported that the key apoptosis related gene caspase 8 (CASP8) is frequently silenced in small cell lung cancer (SCLC) tumors and cell lines…”
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Integrated microarray and multiplex cytokine analyses of Kaposi's Sarcoma Associated Herpesvirus viral FLICE Inhibitory Protein K13 affected genes and cytokines in human blood vascular endothelial cells by Punj, Vasu, Matta, Hittu, Schamus, Sandra, Chaudhary, Preet M

“…Kaposi's sarcoma (KS) associated herpesvirus (KSHV) is the etiological agent of KS, a neoplasm characterized by proliferating spindle cells, extensive…”
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Kaposi sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 cooperates with Myc to promote lymphoma in mice by Ahmad, Anwaar, Groshong, Jason S., Matta, Hittu, Schamus, Sandra, Punj, Vasu, Robinson, Lisa J., Gill, Parkash S., Chaudhary, Preet M.

“…Primary effusion lymphoma (PEL) is an aggressive form of lymphoma that is associated with infection by Kaposi's sarcoma-associated herpesvirus (KSHV). One of…”
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Use of Lentiviral Vectors for Delivery of Small Interfering RNA by Matta, Hittu, Hozayev, Berdymammet, Tomar, Raghuvir, Chugh, Priti, Chaudhary, Preet M.

“…Silencing of gene expression by small interfering RNAs (siRNAs) is rapidly becoming a powerful tool for genetic analysis of mammalian cells. Although in the…”
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Kaposi's sarcoma associated herpes virus-encoded viral FLICE inhibitory protein activates transcription from HIV-1 Long Terminal Repeat via the classical NF-κB pathway and functionally cooperates with Tat by Sun, Qinmiao, Matta, Hittu, Chaudhary, Preet M

“…Abstract Background The nuclear transcription factor NF-κB binds to the HIV-1 long terminal repeat (LTR) and is a key regulator of HIV-1 gene expression in…”
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A Purine Scaffold HSP90 Inhibitor BIIB021 Has Selective Activity against KSHV-Associated Primary Effusion Lymphoma and Blocks vFLIP K13-Induced NF-κB by GOPALAKRISHNAN, Ramakrishnan, MATTA, Hittu, CHAUDHARY, Preet M

“…Kaposi sarcoma-associated herpes virus (KSHV)-associated primary effusion lymphomas (PEL) have extremely poor prognosis when treated with conventional…”
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