Search Results - "MATSUTANI, Takaji"

Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity by Shalapour, Shabnam, Lin, Xue-Jia, Bastian, Ingmar N., Brain, John, Burt, Alastair D., Aksenov, Alexander A., Vrbanac, Alison F., Li, Weihua, Perkins, Andres, Matsutani, Takaji, Zhong, Zhenyu, Dhar, Debanjan, Navas-Molina, Jose A., Xu, Jun, Loomba, Rohit, Downes, Michael, Yu, Ruth T., Evans, Ronald M., Dorrestein, Pieter C., Knight, Rob, Benner, Christopher, Anstee, Quentin M., Karin, Michael

“…IgA + B cells expressing programmed death ligand 1 (PD-L1) and interleukin 10 accumulate in the inflamed livers of humans and mice with non-alcoholic fatty…”
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Editorial: Novel biomarkers in tumor immunity and immunotherapy by Matsutani, Takaji, Akbay, Esra, Elkord, Eyad

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Different Somatic Hypermutation Levels among Antibody Subclasses Disclosed by a New Next-Generation Sequencing-Based Antibody Repertoire Analysis by Kitaura, Kazutaka, Yamashita, Hiroshi, Ayabe, Hitomi, Shini, Tadasu, Matsutani, Takaji, Suzuki, Ryuji

“…A diverse antibody repertoire is primarily generated by the rearrangement of V, D, and J genes and subsequent somatic hypermutation (SHM). Class-switch…”
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Skewing of the B cell receptor repertoire in myalgic encephalomyelitis/chronic fatigue syndrome by Sato, Wakiro, Ono, Hirohiko, Matsutani, Takaji, Nakamura, Masakazu, Shin, Isu, Amano, Keiko, Suzuki, Ryuji, Yamamura, Takashi

“…•ME/CFS is characterized by skewed B cell receptor gene usage.•Upregulation of specific IGHV genes correlated to infection-related episodes at…”
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Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis by Ziegler, Paul K., Bollrath, Julia, Pallangyo, Charles K., Matsutani, Takaji, Canli, Özge, De Oliveira, Tiago, Diamanti, Michaela A., Müller, Nina, Gamrekelashvili, Jaba, Putoczki, Tracy, Horst, David, Mankan, Arun K., Öner, Meryem G., Müller, Susanna, Müller-Höcker, Josef, Kirchner, Thomas, Slotta-Huspenina, Julia, Taketo, M. Mark, Reinheckel, Thomas, Dröse, Stefan, Larner, Andrew C., Wels, Winfried S., Ernst, Matthias, Greten, Tim F., Arkan, Melek C., Korn, Thomas, Wirth, Dagmar, Greten, Florian R.

“…In colorectal cancer patients, a high density of cytotoxic CD8+ T cells in tumors is associated with better prognosis. Using a Stat3 loss-of-function approach…”
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Clinical significance of peripheral TCR and BCR repertoire diversity in EGFR/ALK wild-type NSCLC treated with anti-PD-1 antibody by Nakahara, Yoshiro, Matsutani, Takaji, Igarashi, Yuka, Matsuo, Norikazu, Himuro, Hidetomo, Saito, Haruhiro, Yamada, Kouzo, Murotani, Kenta, Hoshino, Tomoaki, Azuma, Koichi, Sasada, Tetsuro

“…Introduction TCR and BCR repertoire diversity plays a critical role in tumor immunity. Thus, analysis of TCR and BCR repertoires might help predict the…”
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Drug free REmission/low disease activity after cessation of tocilizumab (Actemra) Monotherapy (DREAM) study by Nishimoto, Norihiro, Amano, Koichi, Hirabayashi, Yasuhiko, Horiuchi, Takahiko, Ishii, Tomonori, Iwahashi, Mitsuhiro, Iwamoto, Masahiro, Kohsaka, Hitoshi, Kondo, Masakazu, Matsubara, Tsukasa, Mimura, Toshihide, Miyahara, Hisaaki, Ohta, Shuji, Saeki, Yukihiko, Saito, Kazuyoshi, Sano, Hajime, Takasugi, Kiyoshi, Takeuchi, Tsutomu, Tohma, Shigeto, Tsuru, Tomomi, Ueki, Yukitaka, Yamana, Jiro, Hashimoto, Jun, Matsutani, Takaji, Murakami, Miho, Takagi, Nobuhiro

“…Abstract Objectives To investigate the duration of remission and low disease activity (LDA) after cessation of tocilizumab (TCZ) treatment in rheumatoid…”
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Landscape of immunoglobulin heavy chain γ gene class switch recombination in patients with adult T-cell leukemia-lymphoma by Hiramatsu, Hiroaki, Nosaka, Kisato, Kusumoto, Shigeru, Nakano, Nobuaki, Choi, Ilseung, Yoshimitsu, Makoto, Imaizumi, Yoshitaka, Hidaka, Michihiro, Sasaki, Hidenori, Makiyama, Junya, Ohtsuka, Eiichi, Jo, Tatsuro, Ogata, Masao, Ito, Asahi, Yonekura, Kentaro, Tatetsu, Hiro, Kato, Takeharu, Kawakita, Toshiro, Suehiro, Youko, Ishitsuka, Kenji, Iida, Shinsuke, Matsutani, Takaji, Nishikawa, Hiroyoshi, Utsunomiya, Atae, Ueda, Ryuzo, Ishida, Takashi

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Analysis of B-cell receptor repertoire to evaluate the immunogenicity of SARS-CoV-2 RBD mRNA vaccine: MAFB-7256a (DS-5670d) by Ohji, Goh, Funakoshi, Yohei, Yakushijin, Kimikazu, Matsutani, Takaji, Sasaki, Tomoki, Kusakabe, Takahiro, Matsumoto, Sakuya, Koyama, Taiji, Nagatani, Yoshiaki, Kurata, Keiji, Kimbara, Shiro, Kiyota, Naomi, Minami, Hironobu

“…A monovalent Omicron XBB.1.5 mRNA RBD analogue vaccine, MAFB-7256a (DS-5670d), was newly developed and approved in Japan in the Spring of 2024 for the…”
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A Novel Synthetic Dual Agonistic Liposomal TLR4/7 Adjuvant Promotes Broad Immune Responses in an Influenza Vaccine With Minimal Reactogenicity by Sato-Kaneko, Fumi, Yao, Shiyin, Lao, Fitzgerald S, Shpigelman, Jonathan, Messer, Karen, Pu, Minya, Shukla, Nikunj M, Cottam, Howard B, Chan, Michael, Chu, Paul J, Burkhart, David, Schoener, Roman, Matsutani, Takaji, Carson, Dennis A, Corr, Maripat, Hayashi, Tomoko

“…The limited efficacy of seasonal influenza vaccines is usually attributed to ongoing variation in the major antigenic targets for protective antibody responses…”
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Immune response to influenza vaccine and pneumococcal polysaccharide vaccine under IL-6 signal inhibition therapy with tocilizumab by Tsuru, Tomomi, Terao, Kimio, Murakami, Miho, Matsutani, Takaji, Suzaki, Midori, Amamoto, Toshiaki, Nakashima, Hitoshi, Akiyama, Azusa, Nishimoto, Norihiro

“…Abstract Objectives. To evaluate humoral immune response to influenza vaccine and polysaccharide pneumococcal vaccine in patients with rheumatoid arthritis…”
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Accumulation of metal-specific T cells in inflamed skin in a novel murine model of chromium-induced allergic contact dermatitis by Shigematsu, Hiroaki, Kumagai, Kenichi, Kobayashi, Hiroshi, Eguchi, Takanori, Kitaura, Kazutaka, Suzuki, Satsuki, Horikawa, Tatsuya, Matsutani, Takaji, Ogasawara, Kouetsu, Hamada, Yoshiki, Suzuki, Ryuji

“…Chromium (Cr) causes delayed-type hypersensitivity reactions possibly mediated by accumulating T cells into allergic inflamed skin, which are called irritants…”
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Characterization of T cell receptors of Th1 cells infiltrating inflamed skin of a novel murine model of palladium-induced metal allergy by Kobayashi, Hiroshi, Kumagai, Kenichi, Eguchi, Takanori, Shigematsu, Hiroaki, Kitaura, Kazutaka, Kawano, Mitsuko, Horikawa, Tatsuya, Suzuki, Satsuki, Matsutani, Takaji, Ogasawara, Kouetsu, Hamada, Yoshiki, Suzuki, Ryuji

“…Metal allergy is categorized as a delayed-type hypersensitivity reaction, and is characterized by the recruitment of lymphocytes into sites of allergic…”
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Genomic sequence analysis of the MHC class I G/F segment in common marmoset (Callithrix jacchus) by Kono, Azumi, Brameier, Markus, Roos, Christian, Suzuki, Shingo, Shigenari, Atsuko, Kametani, Yoshie, Kitaura, Kazutaka, Matsutani, Takaji, Suzuki, Ryuji, Inoko, Hidetoshi, Walter, Lutz, Shiina, Takashi

“…The common marmoset (Callithrix jacchus) is a New World monkey that is used frequently as a model for various human diseases. However, detailed knowledge about…”
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Analysis of B‐cell receptor repertoire to evaluate immunogenicity of monovalent Omicron XBB.1.5 mRNA vaccines by Funakoshi, Yohei, Yakushijin, Kimikazu, Ohji, Goh, Matsutani, Takaji, Doi, Kazuhiko, Sakai, Hironori, Sasaki, Tomoki, Kusakabe, Takahiro, Matsumoto, Sakuya, Saito, Yasuyuki, Kawamoto, Shinichiro, Yamamoto, Katsuya, Koyama, Taiji, Nagatani, Yoshiaki, Kurata, Keiji, Kimbara, Shiro, Imamura, Yoshinori, Kiyota, Naomi, Ito, Mitsuhiro, Minami, Hironobu

“…Monovalent Omicron XBB.1.5 mRNA vaccines were newly developed and approved by the FDA in Autumn 2023 for preventing COVID‐19. However, clinical efficacy for…”
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Immune-related gene expression profile in laboratory common marmosets assessed by an accurate quantitative real-time PCR using selected reference genes by Fujii, Yoshiki, Kitaura, Kazutaka, Matsutani, Takaji, Shirai, Kenji, Suzuki, Satsuki, Takasaki, Tomohiko, Kumagai, Kenichi, Kametani, Yoshie, Shiina, Takashi, Takabayashi, Shuji, Katoh, Hideki, Hamada, Yoshiki, Kurane, Ichiro, Suzuki, Ryuji

“…The common marmoset (Callithrix jacchus) is considered a novel experimental animal model of non-human primates. However, due to antibody unavailability,…”
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Massive surge of mRNA expression of clonal B-cell receptor in patients with COVID-19 by Funakoshi, Yohei, Ohji, Goh, Yakushijin, Kimikazu, Ebisawa, Kei, Arakawa, Yu, Saegusa, Jun, Matsumoto, Hisayuki, Imanishi, Takamitsu, Fukuda, Eriko, Matsutani, Takaji, Mori, Yasuko, Iwata, Kentaro, Minami, Hironobu

“…Antibody production is one of the primary mechanisms for recovery from coronavirus disease 2019 (COVID-19). It is speculated that massive clonal expansion of B…”
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Arthritis and pneumonitis produced by the same T cell clones from mice with spontaneous autoimmune arthritis by Wakasa-Morimoto, Chiaki, Toyosaki-Maeda, Tomoko, Matsutani, Takaji, Yoshida, Ryu, Nakamura-Kikuoka, Shino, Maeda-Tanimura, Miki, Yoshitomi, Hiroyuki, Hirota, Keiji, Hashimoto, Motomu, Masaki, Hideyuki, Fujii, Yoshiki, Sakata, Tsuneaki, Tsuruta, Yuji, Suzuki, Ryuji, Sakaguchi, Noriko, Sakaguchi, Shimon

“…SKG mice, a newly established model of rheumatoid arthritis (RA), spontaneously develop autoimmune arthritis accompanying extra-articular manifestations, such…”
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Retreatment efficacy and safety of tocilizumab in patients with rheumatoid arthritis in recurrence (RESTORE) study by Nishimoto, Norihiro, Amano, Koichi, Hirabayashi, Yasuhiko, Horiuchi, Takahiko, Ishii, Tomonori, Iwahashi, Mitsuhiro, Iwamoto, Masahiro, Kohsaka, Hitoshi, Kondo, Masakazu, Matsubara, Tsukasa, Mimura, Toshihide, Miyahara, Hisaaki, Ohta, Shuji, Saeki, Yukihiko, Saito, Kazuyoshi, Sano, Hajime, Takasugi, Kiyoshi, Takeuchi, Tsutomu, Tohma, Shigeto, Tsuru, Tomomi, Ueki, Yukitaka, Yamana, Jiro, Hashimoto, Jun, Matsutani, Takaji, Murakami, Miho, Takagi, Nobuhiro

“…Abstract Objectives To evaluate the safety and efficacy of retreatment with tocilizumab (TCZ) in patients who had participated in the DREAM study (Drug free…”
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T-cell Responses to Dengue Virus in Humans by Kurane, Ichiro, Matsutani, Takaji, Suzuki, Ryuji, Takasaki, Tomohiko, Kalayanarooj, Siripen, Green, Sharone, Rothman, Alan L., Ennis, Francis A.

“…Dengue virus (DENV) is a leading cause of morbidity and mortality in most tropical and subtropical areas of the world. Dengue virus infection induces specific…”
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