Search Results - "MATSUTANI, Masao"
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Consensus on the management of intracranial germ-cell tumours
Published in The lancet oncology (01-09-2015)“…Summary The management of intracranial germ-cell tumours is complex because of varied clinical presentations, tumour sites, treatments and outcomes, and the…”
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Comparison on epidemiology, tumor location, histology, and prognosis of intracranial germ cell tumors between Mayo Clinic and Japanese consortium cohorts
Published in Journal of neurosurgery (01-02-2021)“…Central nervous system (CNS) germ cell tumors (GCTs) are rare malignant neoplasms that arise predominantly in adolescents and young adults. CNS GCTs…”
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Integrated clinical, histopathological, and molecular data analysis of 190 central nervous system germ cell tumors from the iGCT Consortium
Published in Neuro-oncology (Charlottesville, Va.) (17-12-2019)“…We integrated clinical, histopathological, and molecular data of central nervous system germ cell tumors to provide insights into their management. Data from…”
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Histopathology and prognosis of germ cell tumors metastatic to brain: cohort study
Published in Journal of neuro-oncology (01-08-2021)“…Introduction Germ cell tumors (GCTs) are uncommon neoplasms predominantly arising in midline tissues. The prognostic significance of histopathology in…”
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12p gain is predominantly observed in non-germinomatous germ cell tumors and identifies an unfavorable subgroup of central nervous system germ cell tumors
Published in Neuro-oncology (Charlottesville, Va.) (04-05-2022)“…Abstract Background Central nervous system (CNS) germ cell tumors (GCTs) are neoplasms predominantly arising in pediatric and young adult populations. While…”
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Current Status of Palliative and Terminal Care for Patients with Primary Malignant Brain Tumors in Japan
Published in Neurologia medico-chirurgica (01-01-2020)“…Palliative care and advance care planning (ACP) from the first diagnosis of glioblastoma are important. This questionnaire survey was conducted to understand…”
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Distinct patterns of copy number alterations may predict poor outcome in central nervous system germ cell tumors
Published in Scientific reports (21-09-2023)“…We have previously reported that 12p gain may predict the presence of malignant components and poor prognosis for CNS germ cell tumor (GCT). Recently, 3p25.3…”
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Phase I/IIa trial of fractionated radiotherapy, temozolomide, and autologous formalin-fixed tumor vaccine for newly diagnosed glioblastoma
Published in Journal of neurosurgery (01-09-2014)“…Temozolomide (TMZ) may enhance antitumor immunity in patients with glioblastoma multiforme (GBM). In this paper the authors report on a prospective Phase I/IIa…”
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Increased expression of podoplanin in malignant astrocytic tumors as a novel molecular marker of malignant progression
Published in Acta neuropathologica (01-05-2006)“…Podoplanin (aggrus) is a mucin-like transmembrane sialoglycoprotein that is expressed on lymphatic endothelial cells. Podoplanin is putatively involved in…”
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Impact of tumor markers on diagnosis, treatment and prognosis in CNS germ cell tumors: correlations with clinical practice and histopathology
Published in Brain tumor pathology (01-04-2023)“…Tumor markers in CNS germ cell tumors (GCTs) include human chorionic gonadotropin (HCG) and alpha fetoprotein (AFP), which have significant diagnostic…”
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Phase II study of single-agent bevacizumab in Japanese patients with recurrent malignant glioma
Published in Japanese journal of clinical oncology (01-10-2012)“…This single-arm, open-label, Phase II study evaluated the efficacy and safety of single-agent bevacizumab, a monoclonal antibody against vascular endothelial…”
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Clinical management of primary central nervous system germ cell tumors
Published in Seminars in oncology (01-10-2004)“…Despite excellent long-term results for patients with germinoma treated with radiation therapy, the potential for late effects makes the treatment…”
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Duration between onset and diagnosis in central nervous system tumors: Impact on prognosis and functional outcome
Published in Pediatrics international (01-12-2014)“…Background The initial presentation of central nervous system (CNS) tumors in children frequently mimics other more common and less serious conditions,…”
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Cadherin 13 overexpression as an important factor related to the absence of tumor fluorescence in 5-aminolevulinic acid-guided resection of glioma
Published in Journal of neurosurgery (01-11-2013)“…Gliomas contain aggressive malignant cancer, and resection rate remains an important factor in treatment. Currently, fluorescence-guided resection using orally…”
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A Multicenter Phase I/II Study of the BCNU Implant (Gliadel® Wafer) for Japanese Patients with Malignant Gliomas
Published in Neurologia medico-chirurgica (2014)“…Carmustine (BCNU) implants (Gliadel® Wafer, Eisai Inc., New Jersey, USA) for the treatment of malignant gliomas (MGs) were shown to enhance overall survival in…”
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Podoplanin expression in primary central nervous system germ cell tumors: a useful histological marker for the diagnosis of germinoma
Published in Acta neuropathologica (01-06-2006)“…Podoplanin, a mucin-like transmembrane sialoglycoprotein, promotes platelet aggregation and may be involved in cancer cell migration, invasion, metastasis, and…”
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Successful treatment of mixed yolk sac tumor and mature teratoma in the spinal cord: case report
Published in Journal of neurosurgery. Spine (01-03-2017)“…Primary spinal germ cell tumors are rare, and spinal nongerminomatous germ cell tumors represent an even rarer subset for which no standard therapy has been…”
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Genome-wide analysis of DNA copy number alterations and loss of heterozygosity in intracranial germ cell tumors
Published in Pediatric blood & cancer (01-04-2014)“…Backgrounds Intracranial germ cell tumors (GCTs) are rare and heterogeneous with very little is known about their pathogenesis and underlying genetic…”
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Human chorionic gonadotropin is expressed virtually in all intracranial germ cell tumors
Published in Journal of neuro-oncology (01-08-2015)“…Human chorionic gonadotropin (hCG) production has been utilized as a diagnostic marker for germinoma with syncytiotrophoblastic giant cells (STGC) and…”
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