Search Results - "MATSUOKA, Masao"

Adult T‐cell leukemia‐lymphoma as a viral disease: Subtypes based on viral aspects by Nosaka, Kisato, Matsuoka, Masao

“…Adult T‐cell leukemia‐lymphoma (ATL) is caused by human T‐cell leukemia virus type 1 (HTLV‐1) infection. Among HTLV‐1 encoded genes, HTLV‐1 bZIP factor (HBZ)…”
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HTLV-1 bZIP factor: the key viral gene for pathogenesis by Matsuoka, Masao, Mesnard, Jean-Michel

“…Human T cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia-lymphoma (ATL) and inflammatory diseases. The HTLV-1 bZIP factor (HBZ) gene is…”
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The noncanonical role of EZH2 in cancer by Huang, Jinhua, Gou, Hongwei, Yao, Jia, Yi, Kaining, Jin, Zhigang, Matsuoka, Masao, Zhao, Tiejun

“…Enhancer of zeste homolog 2 (EZH2) is the catalytic subunit of polycomb repressive complex 2 (PRC2). Dysregulation of EZH2 causes alteration of gene expression…”
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Functional and Pathogenic Roles of Retroviral Antisense Transcripts by Toyoda, Kosuke, Matsuoka, Masao

“…Exogenous retroviruses such as human immunodeficiency virus type 1 (HIV-1), human T-cell leukemia virus type 1 (HTLV-1) and bovine leukemia virus (BLV) can…”
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An IL‐27/Stat3 axis induces expression of programmed cell death 1 ligands (PD‐L1/2) on infiltrating macrophages in lymphoma by Horlad, Hasita, Ma, Chaoya, Yano, Hiromu, Pan, Cheng, Ohnishi, Koji, Fujiwara, Yukio, Endo, Shinya, Kikukawa, Yoshitaka, Okuno, Yutaka, Matsuoka, Masao, Takeya, Motohiro, Komohara, Yoshihiro

“…Immune escape and tolerance in the tumor microenvironment are closely involved in tumor progression, and are caused by T‐cell exhaustion and mediated by the…”
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40 years of the human T-cell leukemia virus: past, present, and future [version 1; peer review: 2 approved] by Tagaya, Yutaka, Matsuoka, Masao, Gallo, Robert

“…It has been nearly 40 years since human T-cell leukemia virus-1 (HTLV-1), the first oncogenic retrovirus in humans and the first demonstrable cause of cancer…”
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Human T-cell leukaemia virus type 1: parasitism and pathogenesis by Bangham, Charles R. M., Matsuoka, Masao

“…Human T-cell leukaemia virus type 1 (HTLV-1) causes not only adult T-cell leukaemia-lymphoma (ATL), but also inflammatory diseases including HTLV-1-associated…”
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Blocking cholesterol efflux mechanism is a potential target for antilymphoma therapy by Yano, Hiromu, Fujiwara, Yukio, Horlad, Hasita, Pan, Chang, Kai, Keitaro, Niino, Daisuke, Ohsawa, Kumiko, Higashi, Morihiro, Nosaka, Kisato, Okuno, Yutaka, Tamaru, Jun‐ichi, Mukasa, Akitake, Matsuoka, Masao, Komohara, Yoshihiro

“…Cholesterol is an essential plasma membrane lipid for the maintenance of cellular homeostasis and cancer cell proliferation. Free cholesterol is harmful to…”
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A novel PDK1 inhibitor, JX06, inhibits glycolysis and induces apoptosis in multiple myeloma cells by Kawano, Yawara, Sasano, Takayuki, Arima, Yuichiro, Kushima, Saki, Tsujita, Kenichi, Matsuoka, Masao, Hata, Hiroyuki

“…Pyruvate dehydrogenase kinase 1 (PDK1) is a Ser/Thr kinase that inactivates mitochondrial pyruvate dehydrogenase (PDH), leading to switch of glucose metabolism…”
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Human T-cell leukemia virus type I and adult T-cell leukemia by Matsuoka, Masao

“…Human T-cell leukemia virus type I (HTLV-I) causes adult T-cell leukemia (ATL) in about 5% of carriers after a long latent period. After its infection, HTLV-I…”
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Multifaceted functions and roles of HBZ in HTLV-1 pathogenesis by Ma, Guangyong, Yasunaga, Jun-Ichirou, Matsuoka, Masao

“…Human T cell leukemia virus type 1 (HTLV-1) is an oncogenic retrovirus responsible for the development of adult T-cell leukemia (ATL). Although HTLV-1 harbors…”
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Oncogenic spiral by infectious pathogens: Cooperation of multiple factors in cancer development by Yasunaga, Jun‐Ichirou, Matsuoka, Masao

“…Chronic infection is one of the major causes of cancer, and there are several mechanisms for infection‐mediated oncogenesis. Some pathogens encode gene…”
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Molecular mechanisms of HTLV-1 infection and pathogenesis by Yasunaga, Junichiro, Matsuoka, Masao

“…Human T cell leukemia virus type 1 (HTLV-1) is an etiological pathogen of several human diseases, including adult T-cell leukemia (ATL), HTLV-1-associated…”
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A Conformational Escape Reaction of HIV-1 against an Allosteric Integrase Inhibitor by Nakamura, Tomofumi, Nakamura, Teruya, Amano, Masayuki, Miyakawa, Toshikazu, Yamagata, Yuriko, Matsuoka, Masao, Nakata, Hirotomo

“…HIV-1 often acquires drug-resistant mutations in spite of the benefits of antiretroviral therapy (ART). HIV-1 integrase (IN) is essential for the concerted…”
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The HBZ gene, a key player in HTLV-1 pathogenesis by Matsuoka, Masao, Green, Patrick L

“…Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL) and is also associated with a variety of lymphocyte-mediated diseases…”
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Effect of 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one-containing lactic acid bacterial beverages on skin moisture: A randomized, double-blind, placebo-controlled, parallel study by Sato, Taiki, Tomizawa, Masato, Segawa, Shuichi, Matsuoka, Masao, Aurues, Takashi

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Human retroviral antisense mRNAs are retained in the nuclei of infected cells for viral persistence by Ma, Guangyong, Yasunaga, Jun-ichirou, Shimura, Kazuya, Takemoto, Keiko, Watanabe, Miho, Amano, Masayuki, Nakata, Hirotomo, Liu, Benquan, Zuo, Xiaorui, Matsuoka, Masao

“…Human retroviruses, including human T cell leukemia virus type 1 (HTLV-1) and HIV type 1 (HIV-1), encode an antisense gene in the negative strand of the…”
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Neutralization activity of sera/IgG preparations from fully BNT162b2 vaccinated individuals against SARS-CoV-2 Alpha, Beta, Gamma, Delta, and Kappa variants by Amano, Masayuki, Otsu, Sachiko, Maeda, Kenji, Uemura, Yukari, Shimizu, Yosuke, Omata, Kazumi, Matsuoka, Masao, Shimada, Shinya, Mitsuya, Hiroaki

“…In the present prospective study, 225 individuals in Kumamoto General Hospital, Japan, who received two-doses of BNT162b2 vaccine were enrolled/followed up…”
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Novel p97/VCP inhibitor induces endoplasmic reticulum stress and apoptosis in both bortezomib‐sensitive and ‐resistant multiple myeloma cells by Nishimura, Nao, Radwan, Mohamed O., Amano, Masayuki, Endo, Shinya, Fujii, Eri, Hayashi, Hironori, Ueno, Shikiko, Ueno, Niina, Tatetsu, Hiro, Hata, Hiroyuki, Okamoto, Yoshinari, Otsuka, Masami, Mitsuya, Hiroaki, Matsuoka, Masao, Okuno, Yutaka

“…p97/VCP is an endoplasmic reticulum (ER)‐associated protein that belongs to the AAA (ATPases associated with diverse cellular activities) ATPase family. It has…”
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A critical role for IL-17RB signaling in HTLV-1 tax-induced NF-κB activation and T-cell transformation by Lavorgna, Alfonso, Matsuoka, Masao, Harhaj, Edward William

“…Human T-cell leukemia virus type 1 (HTLV-1) infection is linked to the development of adult T-cell leukemia (ATL) and the neuroinflammatory disease HTLV-1…”
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