Search Results - "MATSUNOBU, Aki"

Cytokeratin immunohistochemistry improves interobserver variability between unskilled pathologists in the evaluation of tumor budding in T1 colorectal cancer by Kai, Keita, Aishima, Shinichi, Aoki, Shigehisa, Takase, Yukari, Uchihashi, Kazuyoshi, Masuda, Masanori, Nishijima-Matsunobu, Aki, Yamamoto, Mihoko, Ide, Kousuke, Nakayama, Atsushi, Yamasaki, Makiko, Toda, Shuji

“…Tumor budding is a major risk factor for T1 colorectal cancer. Quality control of the pathological diagnosis of budding is crucial, irrespective of the…”
Get full text

Two autopsy cases of desmoplastic small round cell tumor by Yamamoto, Yohei, Nishijima‐Matsunobu, Aki, Hiroshima, Yuko, Enomoto, Katsuhiko, Inoue, Masahiro, Muto, Osamu, Suzuki, Maya, Nanjo, Hiroshi, Shibata, Hiroyuki, Omori, Yasufumi

“…Desmoplastic small round cell tumor (DSRCT) is a rare aggressive malignant tumor. It is a refractory tumor and the median overall survival is very short. We…”
Get full text

A curcumin analogue GO‐Y030 depletes cancer stem cells by inhibiting the interaction between the HSP70/HSP40 complex and its substrates by Suzuki, Maya, Yamamoto, Yohei, Nishijima‐Matsunobu, Aki, Kawasaki, Yohei, Shibata, Hiroyuki, Omori, Yasufumi

“…Cancer stem cells (CSCs) are proposed to be involved in tumor initiation and play important roles in cancer relapse, metastasis, and drug resistance…”
Get full text

Histopathology of tenosynovium in trigger fingers by Uchihashi, Kazuyoshi, Tsuruta, Toshiyuki, Mine, Hiroko, Aoki, Shigehisa, Nishijima-Matsunobu, Aki, Yamamoto, Mihoko, Kuraoka, Akio, Toda, Shuji

“…Stenosing flexor tenosynovitis, trigger finger, is a common clinical disorder causing painful locking or contracture of the involved digits, and most instances…”
Get full text

Differential effects of adipose tissue stromal cells on the apoptosis, growth and invasion of bladder urothelial carcinoma between the superficial and invasive types by Kawasaki-Nanri, Maki, Aoki, Shigehisa, Uchihashi, Kazuyoshi, Yamamoto, Mihoko, Udo, Kazuma, Nishijima-Matsunobu, Aki, Kakihara, Nahoko, Noguchi, Mitsuru, Uozumi, Jiro, Toda, Shuji

“…Objectives To clarify the interaction between adipose tissue stromal cells and bladder cancer cells. Methods Superficial (RT4) and invasive (EJ) urothelial…”
Get full text

Phosphaturic mesenchymal tumor, nonphosphaturic variant, causing fatal pulmonary metastasis by Uchihashi, Kazuyoshi, MD, PhD, Nishijima-Matsunobu, Aki, MD, PhD, Matsuyama, Atsuji, MD, PhD, Yamasaki, Fumio, MD, PhD, Tanabe, Tsuyoshi, MD, Uemura, Tetsuji, MD, PhD, Aragane, Naoko, MD, PhD, Yakushiji, Mai, MD, Yamamoto, Mihoko, MD, Aoki, Shigehisa, MD, PhD, Toda, Shuji, MD, PhD

“…Summary Phosphaturic mesenchymal tumors of the mixed connective tissue type (PMT-MCTs) are rare neoplasms, most of which are benign and cause tumor-induced…”
Get full text

A Promising Culture Model for Analyzing the Interaction between Adipose Tissue and Cardiomyocytes by Anan, Mayumi, Uchihashi, Kazuyoshi, Aoki, Shigehisa, Matsunobu, Aki, Ootani, Akifumi, Node, Koichi, Toda, Shuji

“…The model described in this study will be a promising tool for investigating adipose tissue-cardiomyocyte interaction, and obesity-related lipotoxicity and…”
Get full text

Interaction between adipose tissue stromal cells and gastric cancer cells in vitro by Nomoto-Kojima, Namie, Aoki, Shigehisa, Uchihashi, Kazuyoshi, Matsunobu, Aki, Koike, Eisuke, Ootani, Akifumi, Yonemitsu, Nobuhisa, Fujimoto, Kazuma, Toda, Shuji

“…Adipose tissue exists in the gastric submucosa and subserosa. Thus, adipose tissue stromal cells (ATSCs), which include mesenchymal stem cells (MSCs), seem…”
Get full text

Interaction between Esophageal Squamous Cell Carcinoma and Adipose Tissue in Vitro by Nakayama, Atsushi, Aoki, Shigehisa, Uchihashi, Kazuyoshi, Nishijima-Matsunobu, Aki, Yamamoto, Mihoko, Kakihara, Nahoko, Iwakiri, Ryuichi, Fujimoto, Kazuma, Toda, Shuji

“…Esophageal squamous cell carcinoma (ESCC) develops within the squamous epithelial layer and invades the submucosa to the subadventitia that has adipose tissue…”
Get full text

Intrinsic Oncogenic Function of Intracellular Connexin26 Protein in Head and Neck Squamous Cell Carcinoma Cells by Iikawa, Nobuko, Yamamoto, Yohei, Kawasaki, Yohei, Nishijima-Matsunobu, Aki, Suzuki, Maya, Yamada, Takechiyo, Omori, Yasufumi

“…It has long been known that the gap junction is down-regulated in many tumours. One of the downregulation mechanisms is the translocation of connexin, a gap…”
Get full text

Prolonged effect of fluid flow stress on the proliferative activity of mesothelial cells after abrupt discontinuation of fluid streaming by Aoki, Shigehisa, Ikeda, Satoshi, Takezawa, Toshiaki, Kishi, Tomoya, Makino, Junichi, Uchihashi, Kazuyoshi, Matsunobu, Aki, Noguchi, Mitsuru, Sugihara, Hajime, Toda, Shuji

“…► Late-onset peritoneal fibrosis leading to EPS remains to be elucidated. ► Fluid streaming is a potent factor for peritoneal fibrosis in PD. ► We focused on…”
Get full text

Adipose tissue behavior is distinctly regulated by neighboring cells and fluid flow stress: a possible role of adipose tissue in peritoneal fibrosis by Aoki, Shigehisa, Udo, Kazuma, Morimoto, Hiroyuki, Ikeda, Satoshi, Takezawa, Toshiaki, Uchihashi, Kazuyoshi, Nishijima-Matsunobu, Aki, Noguchi, Mitsuru, Sugihara, Hajime, Toda, Shuji

“…Adipose tissue, together with the mesothelial layer and microvessels, is a major component of the mesenteric peritoneum, and the mesenterium is a target site…”
Get full text

FLUID FLOW STRESS AFFECTS PERITONEAL CELL KINETICS: POSSIBLE PATHOGENESIS OF PERITONEAL FIBROSIS by AOKI, Shigehisa, MAKINO, Junichi, NAGASHIMA, Akinori, TAKEZAWA, Toshiaki, NOMOTO, Namie, UCHIHASHI, Kazuyoshi, MATSUNOBU, Aki, SANAI, Toru, SUGIHARA, Hajime, TODA, Shuji

“…Peritoneal fibrosis is an essential precursor condition to the development of encapsulating peritoneal sclerosis (EPS). This serious complication leads to a…”
Get full text

The Apoptotic Effect of HIF-1α Inhibition Combined with Glucose plus Insulin Treatment on Gastric Cancer under Hypoxic Conditions by Tanaka, Tomokazu, Kitajima, Yoshihiko, Miyake, Shuusuke, Yanagihara, Kazuyoshi, Hara, Hiromitsu, Nishijima-Matsunobu, Aki, Baba, Koichi, Shida, Masaaki, Wakiyama, Kota, Nakamura, Jun, Noshiro, Hirokazu

“…Gastric cancer grows under a hypoxic environment. HIF-1α is known to play an important role in controlling the production of reactive oxygen species (ROS) in…”
Get full text

Three-dimensional culture model for analyzing crosstalk between adipose tissue and hepatocytes by Nishijima-Matsunobu, Aki, Aoki, Shigehisa, Uchihashi, Kazuyoshi, Fujimoto, Kazuma, Toda, Shuji

“…Systemic adipose tissue is involved in the pathophysiology of obesity-associated liver diseases. However, a method has not been established for analyzing the…”
Get full text

Comparison of the effects of omeprazole and famotidine in treatment of upper abdominal symptoms in patients with reflux esophagitis by Kusunoki, Hiroaki, Kusaka, Masayasu, Kido, Soichiro, Yamauchi, Ryo, Fujimura, Yoshinori, Watanabe, Yasuyuki, Kobori, Michio, Miwa, Hiroto, Tomita, Toshihiko, Kin, Yongmin, Hori, Kazutoshi, Tano, Nobuo, Sugimoto, Kenji, Nakamura, Yoshihiro, Fujimoto, Kazuma, Oza, Noriko, Matsunobu, Aki, Ono, Naofumi, Fuyuno, Seisuke, Kinoshita, Yoshikazu, Adachi, Kyoichi, Yuki, Mika, Fujisawa, Tomoo, Haruma, Ken

“…Purpose The purpose of this study was to compare the efficacy of proton pump inhibitor (PPI) with H₂ receptor antagonist (H₂RA) in treatment of upper abdominal…”
Get full text

The Air Liquid-interface, a Skin Microenvironment, Promotes Growth of Melanoma Cells, but not Their Apoptosis and Invasion, through Activation of Mitogen-activated Protein Kinase by Yee, Chong Hong, Aoki, Shigehisa, Uchihashi, Kazuyoshi, Matsunobu, Aki, Yamasaki, Fumio, Misago, Noriyuki, Piao, Meihua, Tetsuji, Uemura, Yonemitsu, Nobuhisa, Sugihara, Hajime, Toda, Shuji

“…The air-liquid interface (ALI) is a common microenvironment of the skin, but it is unknown whether the ALI affects melanoma cell behaviors. Using a collagen…”
Get full text

Osteoblast migration into type I collagen gel and differentiation to osteocyte-like cells within a self-produced mineralized matrix: A novel system for analyzing differentiation from osteoblast to osteocyte by Uchihashi, Kazuyoshi, Aoki, Shigehisa, Matsunobu, Aki, Toda, Shuji

“…Abstract Osteoblasts are believed to differentiate into osteocytes, becoming embedded in bone, or to undergo apoptosis after the bone formation phase. The…”
Get full text

Corrigendum to “Osteoblast migration into type I collagen gel and differentiation to osteocyte-like cells within a self-produced mineralized matrix: A novel system for analyzing differentiation from osteoblast to osteocyte” [Bone 52 (2013) 102–110] by Uchihashi, Kazuyoshi, Aoki, Shigehisa, Matsunobu, Aki, Toda, Shuji

Get full text

The Apoptotic Effect of HIF-1[alpha] Inhibition Combined with Glucose plus Insulin Treatment on Gastric Cancer under Hypoxic Conditions by Tanaka, Tomokazu, Kitajima, Yoshihiko, Miyake, Shuusuke, Yanagihara, Kazuyoshi, Hara, Hiromitsu, Nishijima-Matsunobu, Aki, Baba, Koichi, Shida, Masaaki, Wakiyama, Kota, Nakamura, Jun, Noshiro, Hirokazu

“…Gastric cancer grows under a hypoxic environment. HIF-1[alpha] is known to play an important role in controlling the production of reactive oxygen species…”
Get full text