Search Results - "MATSUMOTO, DAISUKE"

Social factors associated with reversing frailty progression in community-dwelling late-stage elderly people: An observational study by Takatori, Katsuhiko, Matsumoto, Daisuke

“…Frailty is considered to be a complex concept based mainly on physical vulnerability, but also vulnerabilities in mental/psychological and social aspects…”
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Molecular Switch Engineering for Precise Genome Editing by Matsumoto, Daisuke, Nomura, Wataru

“…Genome editing technology commenced in 1996 with the discovery of the first zinc-finger nuclease. Application of Clustered Regularly Interspaced Short…”
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2D coherent charge transport in highly ordered conducting polymers doped by solid state diffusion by Kang, Keehoon, Watanabe, Shun, Broch, Katharina, Sepe, Alessandro, Brown, Adam, Nasrallah, Iyad, Nikolka, Mark, Fei, Zhuping, Heeney, Martin, Matsumoto, Daisuke, Marumoto, Kazuhiro, Tanaka, Hisaaki, Kuroda, Shin-ichi, Sirringhaus, Henning

“…Doping is one of the most important methods to control charge carrier concentration in semiconductors. Ideally, the introduction of dopants should not perturb…”
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Effects of social activity participation and trust in the community on the transition of frailty classification in late-stage older adults: a 4-year prospective cohort study by Takatori, Katsuhiko, Matsumoto, Daisuke

“…ObjectivesIn Japan, frailty is a major risk factor for requiring long-term care, especially among older adults aged 75 years or older (ie, late-stage older…”
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Screening cutoff values to identify the risk of falls after stroke: A scoping review by Matsumoto, Daisuke, Fujita, Takaaki, Kasahara, Ryuichi, Tsuchiya, Kenji, Iokawa, Kazuaki

“…The present scoping review aimed to summarize and determine the accuracy of the variables and cutoff values reported to date for identifying fall risk in…”
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CRISPRa Analysis of Phosphoinositide Phosphatases Shows That TMEM55A Is a Positive Regulator of Autophagy by Nigorikawa, Kiyomi, Fukushima, Yu, Shimada, Chinatsu, Matsumoto, Daisuke, Nomura, Wataru

“…Transcriptional activation, based on Clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9) and known as CRISPR…”
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Cas9‐Geminin and Cdt1‐fused anti‐CRISPR protein synergistically increase editing accuracy by Matsumoto, Daisuke, Kishi, Kanae, Matsugi, Erina, Inoue, Yuto, Nigorikawa, Kiyomi, Nomura, Wataru

“…Genome editing with CRISPR‐Cas9, particularly for therapeutic purposes, should be accomplished via the homology‐directed repair (HDR) pathway, which exhibits…”
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TALEN-Based Chemically Inducible, Dimerization-Dependent, Sequence-Specific Nucleases by Matsumoto, Daisuke, Tamamura, Hirokazu, Nomura, Wataru

“…For precise genome editing, it is important to control the activity of sequence-specific nucleases. We have constructed a chemically inducible nuclease system…”
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Regional Differences in Disability Incidence among Japanese Adults Aged 75 Years and Older: A 4-Year Prospective Cohort Study by Matsumoto, Daisuke, Takatori, Katsuhiko

“…The present prospective study investigated the regional differences and trajectories of new-onset disabilities among older adults in the districts within a…”
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Efficient and Orthogonal Transcription Regulation by Chemically Inducible Artificial Transcription Factors by Nomura, Wataru, Matsumoto, Daisuke, Sugii, Taisuke, Kobayakawa, Takuya, Tamamura, Hirokazu

“…The DNA-binding specificity of genome editing tools can be applied to gene regulation. Recently, multiple artificial transcription factors (ATFs) were shown to…”
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The pathological function of neutrophils in pemphigoid diseases by Matsumoto, Daisuke, Amatya, Beni, Tsuruta, Daisuke, Hiroyasu, Sho

“…Abstract Pemphigoid diseases (PDs) are a group of autoimmune blistering diseases, including bullous pemphigoid, epidermolysis bullosa acquisita, mucous…”
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Functional interplay between MYCN, NCYM, and OCT4 promotes aggressiveness of human neuroblastomas by Kaneko, Yoshiki, Suenaga, Yusuke, Islam, S. M. Rafiqul, Matsumoto, Daisuke, Nakamura, Yohko, Ohira, Miki, Yokoi, Sana, Nakagawara, Akira

“…Neuroblastoma is a pediatric solid tumor that originates from embryonic neural crest cells. The MYCN gene locus is frequently amplified in unfavorable…”
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A cell cycle-dependent CRISPR-Cas9 activation system based on an anti-CRISPR protein shows improved genome editing accuracy by Matsumoto, Daisuke, Tamamura, Hirokazu, Nomura, Wataru

“…The development of genome editing systems based on the Cas9 endonuclease has greatly facilitated gene knockouts and targeted genetic alterations. Precise…”
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Characterization of Structure and Cellular Components of Aspirated and Excised Adipose Tissue by Eto, Hitomi, Suga, Hirotaka, Matsumoto, Daisuke, Inoue, Keita, Aoi, Noriyuki, Kato, Harunosuke, Araki, Jun, Yoshimura, Kotaro

“…Adipose tissue is an easily accessible tissue for use as a soft-tissue filler and source of adult multipotent cells, called adipose-derived…”
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Influences of Centrifugation on Cells and Tissues in Liposuction Aspirates: Optimized Centrifugation for Lipotransfer and Cell Isolation by Kurita, Masakazu, Matsumoto, Daisuke, Shigeura, Tomokuni, Sato, Katsujiro, Gonda, Koichi, Harii, Kiyonori, Yoshimura, Kotaro

“…Although injective autologous fat transplantation is one of the most attractive options for soft-tissue augmentation, problems such as unpredictability and…”
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Characterization of freshly isolated and cultured cells derived from the fatty and fluid portions of liposuction aspirates by Yoshimura, Kotaro, Shigeura, Tomokuni, Matsumoto, Daisuke, Sato, Takahiro, Takaki, Yasuyuki, Aiba-Kojima, Emiko, Sato, Katsujiro, Inoue, Keita, Nagase, Takashi, Koshima, Isao, Gonda, Koichi

“…Liposuction aspirates (primarily saline solution, blood, and adipose tissue fragments) separate into fatty and fluid portions. Cells isolated from the fatty…”
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SpCas9-HF1 enhances accuracy of cell cycle-dependent genome editing by increasing HDR efficiency, and by reducing off-target effects and indel rates by Matsumoto, Daisuke, Matsugi, Erina, Kishi, Kanae, Inoue, Yuto, Nigorikawa, Kiyomi, Nomura, Wataru

“…In genome editing, it is important to avoid off-target mutations so as to reduce unexpected side effects, especially for therapeutic applications. Recently,…”
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Sedentary behaviour may cause differences in physical outcomes and activities of daily living in older cardiovascular disease patients participating in phase I cardiac rehabilitation by Izawa, Kazuhiro P., Ishihara, Kodai, Kanejima, Yuji, Kitamura, Masahiro, Ogura, Asami, Kubo, Ikko, Oka, Koichiro, Brubaker, Peter H., Nagashima, Hitomi, Tawa, Hideto, Matsumoto, Daisuke, Shimizu, Ikki

“…This study aimed to investigate the rate of sedentary behaviour and differences in physical outcomes and activities of daily living (ADL) based on sedentary…”
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Low-intensity resistance training to improve knee extension strength in community-dwelling older adults: Systematic review and meta-analysis of randomized controlled studies by Kamiya, Midori, Ihira, Hikaru, Taniguchi, Yoshiaki, Matsumoto, Daisuke, Ishigaki, Tomoya, Okamae, Akio, Ogawa, Tatsuya, Misu, Shogo, Miyashita, Toshinori, Ohnuma, Takeshi, Chibana, Tomohisa, Morikawa, Natsu, Ikezoe, Tome, Makizako, Hyuma

“…The purpose of this systematic review and meta-analysis was to investigate the effects of low-intensity resistance training on knee extension strength with…”
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The Relationship Between Toe Grip Strength and Dynamic Balance or Functional Mobility Among Community-Dwelling Japanese Older Adults: A Cross-Sectional Study by Uritani, Daisuke, Fukumoto, Takahiko, Matsumoto, Daisuke, Shima, Masayuki

“…Evaluating toe flexor strength may be an important method for predicting and preventing walking dysfunction and falls, particularly among older adults. In this…”
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