Search Results - "MATINING, Roy M"
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Efficacy of a nucleoside-sparing regimen of darunavir/ ritonavir plus raltegravir in treatment-naive HIV-1-infected patients (ACTG A5262)
Published in AIDS (London) (13-11-2011)“…To explore darunavir/ritonavir (DRV/r) plus raltegravir (RAL) combination therapy in antiretroviral-naive patients. Phase IIb, single-arm, open-label,…”
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Older age is associated with peripheral blood expansion of naïve B cells in HIV-infected subjects on antiretroviral therapy
Published in PloS one (10-09-2014)“…Older HIV infected subjects were previously found to have significant B cell expansion during initial antiretroviral therapy in a prospective…”
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Wilms' tumor 1 (WT1) antigen is overexpressed in Kaposi Sarcoma and is regulated by KSHV vFLIP
Published in PLoS pathogens (01-01-2024)“…In people living with HIV, Kaposi Sarcoma (KS), a vascular neoplasm caused by KS herpesvirus (KSHV/HHV-8), remains one of the most common malignancies…”
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Adverse Impact of HIV-1 on Long-term Outcomes Following HCV DAA Treatment: Final Results of ACTG A5320, the Viral Hepatitis C Infection Long-term Cohort Study (VHICS)
Published in Open forum infectious diseases (01-03-2023)“…Abstract Background Long-term outcome data after hepatitis C virus (HCV) treatment are limited, particularly for comparisons between persons with and without…”
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The Effect of Chloroquine on Immune Activation and Interferon Signatures Associated with HIV-1
Published in AIDS research and human retroviruses (01-07-2016)“…Immune activation associated with HIV-1 infection contributes to morbidity and mortality. We studied whether chloroquine, through Toll-like receptor (TLR)…”
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Safety, Tolerability, and Immunogenicity of Repeated Doses of DermaVir, a Candidate Therapeutic HIV Vaccine, in HIV-Infected Patients Receiving Combination Antiretroviral Therapy: Results of the ACTG 5176 Trial
Published in Journal of acquired immune deficiency syndromes (1999) (01-12-2013)“…BACKGROUND:HIV-specific cellular immune responses are associated with control of viremia and delayed disease progression. An effective therapeutic vaccine…”
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Continued Low Rates of Hepatitis C Virus (HCV) Recurrence in HCV/HIV- and HCV-Infected Participants Who Achieved Sustained Virologic Response After Direct-Acting Antiviral Treatment: Final Results From the AIDS Clinical Trials Group A5320 Viral Hepatitis C Infection Long-term Cohort Study (V-HICS)
Published in Open forum infectious diseases (01-12-2021)“…Abstract Final results from the long-term Viral Hepatitis C Infection Long-term Cohort Study (V-HICS) found low rates of hepatitis C virus (HCV) recurrence…”
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The Safety and Immunogenicity of an Interleukin-12–Enhanced Multiantigen DNA Vaccine Delivered by Electroporation for the Treatment of HIV-1 Infection
Published in Journal of acquired immune deficiency syndromes (1999) (01-02-2016)“…BACKGROUND:Therapeutic vaccination is being studied in eradication and “functional cure” strategies for HIV-1. The Profectus Biosciences multiantigen (MAG)…”
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Similar Low Rates of HCV Recurrence in HCV/HIV- and HCV-Infected Participants who Achieved SVR After DAA Treatment: Interim Results From the ACTG A5320 Viral Hepatitis C Infection Long-term Cohort Study (V-HICS)
Published in Open forum infectious diseases (01-06-2018)“…Abstract Hepatitis C virus (HCV) recurrence rates were similar between those with HCV/HIV co-infection (0.35/100 person-years) and HCV infection (0.42/100…”
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Older HIV-infected patients on antiretroviral therapy have B-cell expansion and attenuated CD4 cell increases with immune activation reduction
Published in AIDS (London) (19-06-2013)“…The contribution of immune activation to accelerated HIV-disease progression in older individuals has not been delineated. Prospective multicenter cohort of…”
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Associations of T cell activation and inflammatory biomarkers with virological response to darunavir/ritonavir plus raltegravir therapy
Published in Journal of antimicrobial chemotherapy (01-08-2013)“…One of the goals of antiretroviral therapy (ART) is to attenuate HIV-induced systemic immune activation and inflammation. We determined the dynamics of…”
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Treatment of advanced AIDS-associated Kaposi sarcoma in resource-limited settings: a three-arm, open-label, randomised, non-inferiority trial
Published in The Lancet (British edition) (11-04-2020)“…Optimal treatment regimens for AIDS-associated Kaposi sarcoma, a frequent contributor to morbidity and mortality among people with HIV, have not been…”
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Comparison of illumina and 454 deep sequencing in participants failing raltegravir-based antiretroviral therapy
Published in PloS one (06-03-2014)“…The impact of raltegravir-resistant HIV-1 minority variants (MVs) on raltegravir treatment failure is unknown. Illumina sequencing offers greater throughput…”
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Older Age Is Associated with Peripheral Blood Expansion of Naive B Cells in HIV-Infected Subjects on Antiretroviral Therapy: e107064
Published in PloS one (01-09-2014)“…Older HIV infected subjects were previously found to have significant B cell expansion during initial antiretroviral therapy in a prospective…”
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Journal Article