Search Results - "MATHIESEN, Geir"
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A bacteriocin-based treatment option for Staphylococcus haemolyticus biofilms
Published in Scientific reports (06-07-2021)“…Bacteriocins are ribosomally-synthesized antimicrobial peptides, showing great potential as novel treatment options for multidrug-resistant pathogens. In this…”
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2
Quantitative comparison of the biomass-degrading enzyme repertoires of five filamentous fungi
Published in Scientific reports (20-11-2020)“…The efficiency of microorganisms to degrade lignified plants is of great importance in the Earth’s carbon cycle, but also in industrial biorefinery processes,…”
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3
Anchoring of heterologous proteins in multiple Lactobacillus species using anchors derived from Lactobacillus plantarum
Published in Scientific reports (15-06-2020)“…Members of the genus Lactobacillus have a long history in food applications and are considered as promising and safe hosts for delivery of medically…”
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Characterization of the Chitinolytic Machinery of Enterococcus faecalis V583 and High-Resolution Structure of Its Oxidative CBM33 Enzyme
Published in Journal of molecular biology (17-02-2012)“…Little information exists for the ability of enterococci to utilize chitin as a carbon source. We show that Enterococcus faecalis V583 can grow on chitin, and…”
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Lactiplantibacillus plantarum as a novel platform for production and purification of integral membrane proteins using RseP as the benchmark
Published in Scientific reports (01-09-2023)“…The present study describes a detailed procedure for expressing and purifying the integral membrane protein RseP using the pSIP system and Lactiplantibacillus…”
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Structure and function of a broad-specificity chitin deacetylase from Aspergillus nidulans FGSC A4
Published in Scientific reports (11-05-2017)“…Enzymatic conversion of chitin, a β-1,4 linked polymer of N -acetylglucosamine, is of major interest in areas varying from the biorefining of chitin-rich waste…”
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Antigen surface display in two novel whole genome sequenced food grade strains, Lactiplantibacillus pentosus KW1 and KW2
Published in Microbial cell factories (11-01-2024)“…Utilization of commensal bacteria for delivery of medicinal proteins, such as vaccine antigens, is an emerging strategy. Here, we describe two novel food-grade…”
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Comparison of the Immunogenic Properties of Lactiplantibacillus plantarum Carrying the Mycobacterial Ag85B-ESAT-6 Antigen at Various Cellular Localizations
Published in Frontiers in microbiology (03-06-2022)“…The bacille Calmette-Guèrin (BCG) vaccine has been used for a century; nonetheless, tuberculosis (TB) remains one of the deadliest diseases in the world. Thus,…”
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Comparison of eight Lactobacillus species for delivery of surface-displayed mycobacterial antigen
Published in Vaccine (08-10-2019)“…Highlights•AgE6-displaying lactobacilli activate human dendritic cells. •Induction of humoral immunity upon intranasal immunization in mice. •Two of…”
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10
Efficient Secretion and Recombinant Production of a Lactobacillal α-amylase in Lactiplantibacillus plantarum WCFS1: Analysis and Comparison of the Secretion Using Different Signal Peptides
Published in Frontiers in microbiology (14-06-2021)“…Lactic acid bacteria (LAB) have been used as starter cultures and producers of enzymes, antimicrobial peptides or metabolites that contribute to the flavor,…”
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11
Lactobacillus plantarum producing a Chlamydia trachomatis antigen induces a specific IgA response after mucosal booster immunization
Published in PloS one (03-05-2017)“…Mucosal immunity is important for the protection against a wide variety of pathogens. Traditional vaccines administered via parenteral routes induce strong…”
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12
Genome-wide analysis of signal peptide functionality in Lactobacillus plantarum WCFS1
Published in BMC genomics (10-09-2009)“…Lactobacillus plantarum is a normal, potentially probiotic, inhabitant of the human gastrointestinal (GI) tract. The bacterium has great potential as…”
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13
Constitutive expression and cell-surface display of a bacterial β-mannanase in Lactobacillus plantarum
Published in Microbial cell factories (25-04-2019)“…Lactic acid bacteria (LAB) are important microorganisms in the food and beverage industry. Due to their food-grade status and probiotic characteristics,…”
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14
Cell Wall Anchoring of a Bacterial Chitosanase in Lactobacillus plantarum Using a Food-Grade Expression System and Two Versions of an LP TG Anchor
Published in International journal of molecular sciences (27-05-2020)“…Lactic acid bacteria (LAB) have attracted increasing interest recently as cell factories for the production of proteins as well as a carrier of proteins that…”
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15
Heterologous protein secretion in Lactobacilli with modified pSIP vectors
Published in PloS one (10-03-2014)“…We describe new variants of the modular pSIP-vectors for inducible gene expression and protein secretion in lactobacilli. The basic functionality of the pSIP…”
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Profiling of microorganism-binding serum antibody specificities in professional athletes
Published in PloS one (25-09-2018)“…The goal of this work was to elucidate similarities between microorganisms from the perspective of the humoral immune system reactivity in professional…”
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Inactivated Lactobacillus plantarum Carrying a Surface-Displayed Ag85B-ESAT-6 Fusion Antigen as a Booster Vaccine Against Mycobacterium tuberculosis Infection
Published in Frontiers in immunology (09-07-2019)“…Vaccination is considered the most effective strategy for controlling tuberculosis (TB). The existing vaccine, the Bacille Calmette-Guérin (BCG), although…”
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18
CRISPR Interference for Rapid Knockdown of Essential Cell Cycle Genes in Lactobacillus plantarum
Published in mSphere (20-03-2019)“…Studies of essential genes in bacteria are often hampered by the lack of accessible genetic tools. This is also the case for , a key species in food and health…”
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Expression of endoglucanases in Pichia pastoris under control of the GAP promoter
Published in Microbial cell factories (18-04-2014)“…Plant-derived biomass is a potential alternative to fossil feedstocks for a greener economy. Enzymatic saccharification of biomass has been studied extensively…”
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Over 2000-Fold Increased Production of the Leaderless Bacteriocin Garvicin KS by Increasing Gene Dose and Optimization of Culture Conditions
Published in Frontiers in microbiology (05-03-2019)“…The leaderless bacteriocin Garvicin KS (GarKS) is a potent antimicrobial, being active against a wide range of important pathogens. GarKS production by the…”
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