Search Results - "MATHEWS, M"

A novel application of deep learning for single-lead ECG classification by Mathews, Sherin M., Kambhamettu, Chandra, Barner, Kenneth E.

“…Detecting and classifying cardiac arrhythmias is critical to the diagnosis of patients with cardiac abnormalities. In this paper, a novel approach based on…”
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Exosome Production Is Key to Neuronal Endosomal Pathway Integrity in Neurodegenerative Diseases by Mathews, Paul M, Levy, Efrat

“…Dysfunction of the endosomal-lysosomal system is a prominent pathogenic factor in Alzheimer's disease (AD) and other neurodevelopmental and neurodegenerative…”
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UGbS-Flex, a novel bioinformatics pipeline for imputation-free SNP discovery in polyploids without a reference genome: finger millet as a case study by Qi, Peng, Gimode, Davis, Saha, Dipnarayan, Schröder, Stephan, Chakraborty, Debkanta, Wang, Xuewen, Dida, Mathews M, Malmberg, Russell L, Devos, Katrien M

“…Research on orphan crops is often hindered by a lack of genomic resources. With the advent of affordable sequencing technologies, genotyping an entire genome…”
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Brain Monitoring and the Depth of Anesthesia: Another Goldilocks Dilemma by Shander, Aryeh, Lobel, Gregg P, Mathews, Donald M

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Sensing the neuronal glycocalyx by glial sialic acid binding immunoglobulin-like lectins by Linnartz-Gerlach, B, Mathews, M, Neumann, H

“…Highlights • Siglecs bind to sialic acids of the intact glycocalyx. • Inhibitory Siglec-signaling keeps glial cells in a homeostatic status. • Microglial…”
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Analgesic efficacy of ultrasound-guided transversus abdominis plane block in patients undergoing open appendicectomy by Niraj, G., Searle, A., Mathews, M., Misra, V., Baban, M., Kiani, S., Wong, M.

“…Background Transversus abdominis plane (TAP) block is a new regional anaesthetic technique that blocks abdominal neural afferents by introducing local…”
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Genome analyses reveal population structure and a purple stigma color gene candidate in finger millet by Devos, Katrien M., Qi, Peng, Bahri, Bochra A., Gimode, Davis M., Jenike, Katharine, Manthi, Samuel J., Lule, Dagnachew, Lux, Thomas, Martinez-Bello, Liliam, Pendergast, Thomas H., Plott, Chris, Saha, Dipnarayan, Sidhu, Gurjot S., Sreedasyam, Avinash, Wang, Xuewen, Wang, Hao, Wright, Hallie, Zhao, Jianxin, Deshpande, Santosh, de Villiers, Santie, Dida, Mathews M., Grimwood, Jane, Jenkins, Jerry, Lovell, John, Mayer, Klaus F. X., Mneney, Emmarold E., Ojulong, Henry F., Schatz, Michael C., Schmutz, Jeremy, Song, Bo, Tesfaye, Kassahun, Odeny, Damaris A.

“…Finger millet is a key food security crop widely grown in eastern Africa, India and Nepal. Long considered a ‘poor man’s crop’, finger millet has regained…”
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Identification of SNP and SSR Markers in Finger Millet Using Next Generation Sequencing Technologies by Gimode, Davis, Odeny, Damaris A, de Villiers, Etienne P, Wanyonyi, Solomon, Dida, Mathews M, Mneney, Emmarold E, Muchugi, Alice, Machuka, Jesse, de Villiers, Santie M

“…Finger millet is an important cereal crop in eastern Africa and southern India with excellent grain storage quality and unique ability to thrive in extreme…”
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Influence of parent concrete on the properties of recycled aggregate concrete by Padmini, A.K., Ramamurthy, K., Mathews, M.S.

“…This paper discusses first the properties of recycled aggregates derived from parent concrete (PC) of three strengths, each of them made with three maximum…”
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Multiplex PCR and Next Generation Sequencing for the Non-Invasive Detection of Bladder Cancer by Ward, Douglas G, Baxter, Laura, Gordon, Naheema S, Ott, Sascha, Savage, Richard S, Beggs, Andrew D, James, Jonathan D, Lickiss, Jennifer, Green, Shaun, Wallis, Yvonne, Wei, Wenbin, James, Nicholas D, Zeegers, Maurice P, Cheng, K K, Mathews, Glenn M, Patel, Prashant, Griffiths, Michael, Bryan, Richard T

“…Highly sensitive and specific urine-based tests to detect either primary or recurrent bladder cancer have proved elusive to date. Our ever increasing knowledge…”
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Manifold Approximating Graph Interpolation of Cardiac Local Activation Time by Hellar, Jennifer, Cosentino, Romain, John, Mathews M., Post, Allison, Buchan, Skylar, Razavi, Mehdi, Aazhang, Behnaam

“…Objective: Local activation time (LAT) mapping of cardiac chambers is vital for targeted treatment of cardiac arrhythmias in catheter ablation procedures…”
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Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits by YANG, Dun-Sheng, STAVRIDES, Philip, PAWLIK, Monika, PETERHOFF, Corrinne M, YANG, Austin J, WILSON, Donald A, GEORGE-HYSLOP, Peter St, WESTAWAY, David, MATHEWS, Paul M, LEVY, Efrat, CUERVO, Ana M, NIXON, Ralph A, MOHAN, Panaiyur S, KAUSHIK, Susmita, KUMAR, Asok, OHNO, Masuo, SCHMIDT, Stephen D, WESSON, Daniel, BANDYOPADHYAY, Urmi, YING JIANG

“…Autophagy, a major degradative pathway for proteins and organelles, is essential for survival of mature neurons. Extensive autophagic-lysosomal pathology in…”
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Apolipoprotein E2 Expression Alters Endosomal Pathways in a Mouse Model With Increased Brain Exosome Levels During Aging by Peng, Katherine Y., Liemisa, Braison, Pasato, Jonathan, D'Acunzo, Pasquale, Pawlik, Monika, Heguy, Adriana, Penikalapati, Sai C., Labuza, Amanda, Pidikiti, Harshitha, Alldred, Melissa J., Ginsberg, Stephen D., Levy, Efrat, Mathews, Paul M.

“…ABSTRACT The polymorphic APOE gene is the greatest genetic determinant of sporadic Alzheimer's disease risk: the APOE4 allele increases risk, while the APOE2…”
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Alzheimer's-related endosome dysfunction in Down syndrome is Aβ-independent but requires APP and is reversed by BACE-1 inhibition by Jiang, Ying, Mullaney, Kerry A, Peterhoff, Corrinne M, Che, Shaoli, Schmidt, Stephen D, Boyer-Boiteau, Anne, Ginsberg, Stephen D, Cataldo, Anne M, Mathews, Paul M, Nixon, Ralph A

“…An additional copy of the β-amyloid precursor protein (APP) gene causes early-onset Alzheimer's disease (AD) in trisomy 21 (DS). Endosome dysfunction develops…”
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Survey of a Salivary Effector in Caterpillars: Glucose Oxidase Variation and Correlation with Host Range by Eichenseer, Herb, Mathews, M. C, Powell, Jaimie S, Felton, Gary W

“…Salivary glucose oxidase (GOX) has been reported in a few insect species where it plays a role in protection against infectious disease. Our recent research…”
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Population genetic structure and migration patterns of the maize pathogenic fungus, Cercospora zeina in East and Southern Africa by Nsibo, David L., Barnes, Irene, Omondi, Dennis O., Dida, Mathews M., Berger, Dave K.

“…[Display omitted] •All 964 isolates from gray leaf spot lesions on maize in Africa were Cercospora zeina.•Rejected hypothesis of single introduction C. zeina…”
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Aβ42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology by Radde, Rebecca, Bolmont, Tristan, Kaeser, Stephan A, Coomaraswamy, Janaky, Lindau, Dennis, Stoltze, Lars, Calhoun, Michael E, Jäggi, Fabienne, Wolburg, Hartwig, Gengler, Simon, Haass, Christian, Ghetti, Bernardino, Czech, Christian, Hölscher, Christian, Mathews, Paul M, Jucker, Mathias

“…We have generated a novel transgenic mouse model on a C57BL/6J genetic background that coexpresses KM670/671NL mutated amyloid precursor protein and L166P…”
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The Endosomal-Lysosomal Pathway Is Dysregulated by APOE4 Expression in Vivo by Nuriel, Tal, Peng, Katherine Y, Ashok, Archana, Dillman, Allissa A, Figueroa, Helen Y, Apuzzo, Justin, Ambat, Jayanth, Levy, Efrat, Cookson, Mark R, Mathews, Paul M, Duff, Karen E

“…Possession of the ε4 allele of apolipoprotein E ( ) is the major genetic risk factor for late-onset Alzheimer's disease (AD). Although numerous hypotheses have…”
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A novel convolutional neural network for reconstructing surface electrocardiograms from intracardiac electrograms and vice versa by Banta, Anton, Cosentino, Romain, John, Mathews M., Post, Allison, Buchan, Skylar, Razavi, Mehdi, Aazhang, Behnaam

“…We propose a novel convolutional neural network framework for mapping a multivariate input to a multivariate output. In particular, we implement our algorithm…”
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Artificial Intelligence and Machine Learning in Cardiac Electrophysiology by John, Mathews M, Banta, Anton, Post, Allison, Buchan, Skylar, Aazhang, Behnaam, Razavi, Mehdi

“…Cardiac electrophysiology requires the processing of several patient-specific data points in real time to provide an accurate diagnosis and determine an…”
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