Search Results - "MATHEW, Ninan T"

Pathophysiology of Chronic Migraine and Mode of Action of Preventive Medications by Mathew, Ninan T.

“…(Headache 2011;51;S2:84‐92) Evidence has accumulated in recent years indicating structural, physiologic, and biochemical alterations in the brain of patients…”
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Botulinum Toxin Type A (BOTOX®) for the Prophylactic Treatment of Chronic Daily Headache: A Randomized, Double-Blind, Placebo-Controlled Trial by Mathew, Ninan T., Frishberg, Benjamin M., Gawel, Marek, Dimitrova, Rozalina, Gibson, John, Turkel, Catherine

“…Objective.—The objective of this study was to evaluate the safety and efficacy of botulinum toxin type A (BoNT‐A; BOTOX®, Allergan, Inc.) for the prophylactic…”
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The Impact of Topiramate on Health-Related Quality of Life Indicators in Chronic Migraine by Dodick, David W., Silberstein, Stephen, Saper, Joel, Freitag, Fred G., Cady, Roger K., Rapoport, Alan M., Mathew, Ninan T., Hulihan, Joseph, Crivera, Concetta, Rupnow, Marcia F.T., Mao, Lian, Finlayson, Gary, Greenberg, Steven J.

“…Background.— Chronic migraine is a disabling primary chronic daily headache disorder that significantly impacts the daily activities of patients with this…”
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A Double-Blind Comparison of OnabotulinumtoxinA (BOTOX®) and Topiramate (TOPAMAX®) for the Prophylactic Treatment of Chronic Migraine: A Pilot Study by Mathew, Ninan T., Jaffri, Sayyed Farhan A.

“…Background.— There is a need for effective prophylactic therapy for chronic migraine (CM) that has minimal side effects. Objective.— To compare the efficacy…”
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Predictors of Response to Botulinum Toxin Type A (BoNTA) in Chronic Daily Headache by Mathew, Ninan T., Kailasam, Jayasree, Meadors, Lori

“…Objective.— To evaluate predictors of response to botulinum toxin type A (BoNTA; BOTOX®, Allergan Inc., Irvine, CA, USA) in patients with chronic daily…”
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The Prophylactic Treatment of Chronic Daily Headache by Mathew, Ninan T.

“…Chronic daily headache (CDH), a heterogeneous group of headache disorders occurring on at least 15 days per month, affects up to 4% to 5% of the general…”
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Botulinum Toxin Type A for the Treatment of Nummular Headache: Four Case Studies by Mathew, Ninan T., Kailasam, Jayasree, Meadors, Lori

“…Objective.— We assessed the efficacy and safety of botulinum toxin type A (BoNTA; BOTOX®: Allergan, Inc., Irvine, CA, USA) in patients with nummular headache…”
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Clinical recognition of allodynia in migraine by MATHEW, Ninan T, KAILASAM, Jayasree, SEIFERT, Tad

“…Allodynia, a manifestation of central sensitization, is not routinely evaluated during clinical interviews even though its therapeutic implications are known…”
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Dynamic optimization of chronic migraine treatment : Current and future options by MATHEW, Ninan T

“…Comparator studies that assess treatment effects in a clinical setting have improved the understanding of the efficacy and tolerability of prophylactic…”
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Efficacy and Tolerability of Almotriptan in Adolescents: A Randomized, Double-Blind, Placebo-Controlled Trial by Linder, Steven L., Mathew, Ninan T., Cady, Roger K., Finlayson, Gary, Ishkanian, Gary, Lewis, Donald W.

“…Objectives.— To assess the efficacy and safety of almotriptan 6.25 mg, 12.5 mg, and 25 mg vs placebo for acute migraine treatment in adolescents. Patients and…”
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Randomized, Controlled Study of Telcagepant in Patients With Migraine and Coronary Artery Disease by Ho, Tony W., Ho, Andrew P., Chaitman, Bernard R., Johnson, Constance, Mathew, Ninan T., Kost, James, Fan, Xiaoyin, Aurora, Sheena K., Brandes, Jan L., Fei, Kaiyin, Beebe, Louise, Lines, Christopher, Krucoff, Mitchell W.

“…Objective.— To evaluate the efficacy of telcagepant in patients with migraine and coronary artery disease. Background.— Calcitonin gene‐related peptide…”
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Early Intervention With Almotriptan Improves Sustained Pain-free Response in Acute Migraine by Mathew, Ninan T.

“…Objective.—To determine whether treatment of migraine with almotriptan, when pain intensity is mild, improves 1‐ and 2‐hour pain‐free and sustained pain‐free…”
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Quantifying the return of headache in triptan-treated migraineurs: an observational study by Sheftell, Fred, Almas, Mary, Weeks, Randall, Mathew, Ninan T, Pitman, Verne, Lipton, Richard B

“…To improve understanding of secondary treatment failure in migraine patients, we evaluated 'headache return' as a novel endpoint to assess returning headaches…”
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Efficacy of Gabapentin in Migraine Prophylaxis by Mathew, Ninan T., Rapoport, Alan, Saper, Joel, Magnus, Leslie, Klapper, Jack, Ramadan, Nabih, Stacey, Brett, Tepper, Stewart

“…Objective.—To compare gabapentin with placebo for use as a prophylactic agent in patients with migraine (with or without aura). Study Design and…”
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A Double-Blind, Randomized, Placebo-Controlled Comparison of Botulinum Toxin Type A Injection Sites and Doses in the Prevention of Episodic Migraine by Saper, Joel R., Mathew, Ninan T., Loder, Elizabeth W., DeGryse, Ronald, VanDenburgh, Amanda M.

“…ABSTRACT Background.  Several randomized, controlled studies have reported benefits of botulinum toxin type A (BoNTA; Allergan Inc., Irvine, CA, USA) over…”
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Prophylaxis of Migraine, Transformed Migraine, and Cluster Headache with Topiramate by Mathew, Ninan T., Kailasam, Jayasree, Meadors, Lori

“…Objective.—To assess the efficacy and tolerability of topiramate for prophylaxis of migraine and cluster headache via a retrospective chart analysis…”
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The Use of Questions to Determine the Presence of Photophobia and Phonophobia During Migraine by Evans, Randolph W., Seifert, Tad, Kailasam, Jayasree, Mathew, Ninan T.

“…Objective.— To investigate whether the use of more detailed close‐ended questions as part of the routine headache history is helpful when patients initially…”
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Fixed-Dose Sumatriptan and Naproxen in Poor Responders to Triptans With a Short Half-Life by Mathew, Ninan T., Landy, Stephen, Stark, Stuart, Tietjen, Gretchen E., Derosier, Frederick J., White, Jonathan, Lener, Shelly E., Bukenya, Deo

“…Objective.— To evaluate efficacy and tolerability of a single, fixed‐dose tablet of sumatriptan 85 mg/naproxen sodium 500 mg (sumatriptan/naproxen sodium) vs…”
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Efficacy and Safety of MAP0004, Orally Inhaled DHE in Treating Migraines With and Without Allodynia by Tepper, Stewart J., Kori, Shashidhar H., Borland, Scott W., Wang, Min H., Hu, Bin, Mathew, Ninan T., Silberstein, Stephen D.

“…Background.— Central sensitization develops once migraine attacks become established and can be clinically detected by the development of cutaneous allodynia…”
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Early Treatment of Migraine With Rizatriptan: A Placebo-Controlled Study by Mathew, Ninan T., Kailasam, Jayasree, Meadors, Lori

“…Objective.—To evaluate the efficacy of rizatriptan when administered early during a migraine attack. Background.—Several studies indicate that triptans are…”
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